Amazon One Medical vs TrimRx
Our featured pick: TrimRx (affiliate partner). In our scoring, Amazon One Medical scores 8.5 and TrimRx 7.7 out of 10, and Amazon One Medical costs less for brand-name Wegovy / Ozempic (about $16,361 a year less; one bills every 4 weeks (13 charges a year), so this compares modeled yearly cost).
WeightLossRankings.org is reader-supported. When you buy through links on our site, we may earn an affiliate commission. Learn more
Key differences
- Price
- Amazon One Medical $199/mo vs TrimRx $1,579/mo for brand-name Wegovy / Ozempic (standing prices, no prepay or separate membership listed · about $16,361 a year less with Amazon One Medical · one bills every 4 weeks (13 charges a year), so this compares modeled yearly cost)
- Coverage
- Amazon One Medical 50 states (TrimRx doesn't publish a state list)
- Included
- Amazon One Medical: clinician visits, shipping (not included: medication, labs); TrimRx: medication, clinician visits, shipping
Amazon One Medical
Best for brand-name GLP-1s with published per-dose cash prices and Amazon Pharmacy delivery
Brand-name Wegovy / Ozempic
$199
billed every 4 weeks
Our score 8.5/10
TrimRx
Affiliate partnerAlso prices compounded semaglutide and tirzepatide
semaglutide
$179
$149 first month
Our score 7.7/10
We may earn a commission if you sign up through these links. Partner status can affect which provider we feature; it never changes a score or a price.
Costs & coverage
Published prices with their terms attached. Yearly figures are modeled from the standing price and billing cadence. A check mark marks the better side, on like-for-like rows only.
Amazon One Medical
TrimRx
Price
Brand Wegovy / Ozempic / month
Better on this row: $199/mo
billed every 4 weeks
$1,579/mo
Brand Wegovy / Ozempic / year (modeled)
Better on this row: $2,587
13 charges
$18,948
Brand Zepbound / Mounjaro / month
Better on this row: $299/mo
billed every 4 weeks
$1,249/mo
Brand Zepbound / Mounjaro / year (modeled)
Better on this row: $3,887
13 charges
$14,988
Semaglutide / month
Not listed
$179/mo
$149 first month
Tirzepatide / month
Not listed
$259/mo
Brand Wegovy pill / Rybelsus / month
$149/mo
Not listed
Brand Foundayo / month
$149/mo
Not listed
Coverage
State availability
50 states
List not published
Oral option listed
Yes
Not listed
Brand-name access listed
Wegovy / Ozempic, Zepbound / Mounjaro, Wegovy pill / Rybelsus, Foundayo
Wegovy / Ozempic, Zepbound / Mounjaro
Included in the price
Clinician visits, shipping
Not included: medication, labs
Medication, clinician visits, shipping
Terms & safety
Price shown
Before intake
Before intake
Lab work
Required
Not disclosed
FDA warning letters
None on record
None on record
Provider facts checked
October 2026
August 2026
Every dose and plan: Amazon One Medical · TrimRx
Get alerted when GLP-1 prices drop
Join the GLP-1 price-watch list — we re-verify 540+ providers' prices on their own sites and email you when tracked prices move.
Which fits your priorities?
Only the points where these two differ, from the table above and each provider’s record.
Choose Amazon One Medical if…
- About $16,361 a year less than TrimRx for brand-name Wegovy / Ozempic at standing prices (one bills every 4 weeks (13 charges a year), so this compares modeled yearly cost)
- Lists brand-name Wegovy pill / Rybelsus and brand-name Foundayo, which TrimRx doesn't price
- Publishes its full state list (50 states)
What to weigh up
- Price doesn't include medication
- Online On-Demand Care is cash-only for medication; insurance needs scheduled visits near a One Medical office
Choose TrimRx if…
- Lists compounded semaglutide and compounded tirzepatide, which Amazon One Medical doesn't price
- Price includes medication; Amazon One Medical's doesn't
- Free shipping with medication delivered to your door monthly — can start as soon as the next day
What to weigh up
- About $16,361 a year more than Amazon One Medical for brand-name Wegovy / Ozempic (one bills every 4 weeks (13 charges a year), so this compares modeled yearly cost)
- No published state list; confirm yours at signup
Explore the scoring factors
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
Amazon One Medical
8.5/10
TrimRx
7.7/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Ready to start? Vetted GLP-1 providers
Vetted telehealth providers that prescribe GLP-1 online.
No insurance needed · vetted by our editors
WeightLossRankings.org is reader-supported. When you buy through links on our site, we may earn an affiliate commission. Learn more
SkinnyRx
Compounded semaglutide or tirzepatide with the consult and free overnight shipping in one price
Read full review →From $149.25/mo
Get started →From $79/mo
Get started →From $179/mo
Get started →Amazon One Medical vs TrimRx: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
Related comparisons
Continue exploring Amazon One Medical and TrimRx head-to-heads in the same category.
- Amazon One Medical vs Vytora Health
- Amazon One Medical vs Collective
- Amazon One Medical vs CoreAge Rx
- TrimRx vs EverSlim
- TrimRx vs Found
- TrimRx vs Enhance MD
Or see the full category ranking.
Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.