TMates vs Vytora Health
An in-depth comparison of two leading GLP-1 Providers
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TMates
Best for: nationwide compounded GLP-1 availability including Puerto Rico
Visit TMates →
Vytora Health
Best for: compounded or brand-name GLP-1 with named pharmacy partners, 50 states
Visit Vytora Health →TMates and Vytora Health are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, Vytora Health starts lower at $150/mo versus $249/mo, and TMates is the option we'd start with for most patients. Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.
Pricing
TMates
Verbatim ladder: 1 Month $249 / 3 Months $217/mo Save 13% $650 / 6 Months $175/mo Save 30% $1050 / 12 Months $158/mo Save 37% $1900. Injectable or Oral, same price. Includes medication and ongoing support; free shipping; cancel anytime. UNCHANGED vs providers.json pricing rows; providers.json description field's '$199/mo' is stale.
Verbatim ladder: 1 Month $297 / 3 Months $267/mo Save 10% $800 / 6 Months $217/mo Save 27% $1299 / 12 Months $167/mo Save 44% $1999. Injectable or Oral, same price. UNCHANGED vs providers.json.
Vytora Health
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What’s included
TMates
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Included
Lab work
Not disclosed
Coaching
Included
Vytora Health
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Included
Lab work
Not disclosed
Coaching
Not disclosed
Score breakdown
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
TMates
6.9/10
Vytora Health
8.4/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Features & Coverage
| Feature | TMates | Vytora Health |
|---|---|---|
| Starting Price | $249/mo | ✓$150/mo |
| Features | 4 features | ✓8 features |
| States Available | 50 | ✓51 |
| Compounded | ✓ Yes | ✓ Yes |
| Brand Name | — | ✓ Yes |
| FSA/HSA Accepted | — | — |
| FDA Warnings | None | None |
About TMates
TMates is a Miami-based telehealth platform offering compounded semaglutide ($249/mo) and tirzepatide ($297/mo) across all 50 states plus Puerto Rico, operating on a messaging-first model with independent licensed prescribers and third-party compounding pharmacies.
Read our full TMates review →About Vytora Health
Vytora Health is a 50-state-plus-DC telehealth platform offering compounded semaglutide and tirzepatide alongside brand-name Mounjaro and Zepbound, plus NAD+ and sermorelin peptides. It names its pharmacy partners publicly — Vials Pharmacy and Greenwich Biosciences — and discloses its operating physician group, uncommon transparency for the category. Compounded semaglutide runs $180/mo ($150 on a 3-month bundle) and tirzepatide $249/mo ($200 bundled).
Read our full Vytora Health review →Pros & Cons
TMates
What we like
- All-inclusive monthly price covers medication, consults, nutrition coaching, and 24/7 support — no separate membership fee
- Available in all 50 states plus Puerto Rico and other US territories
- Both compounded semaglutide and tirzepatide offered
- Fast stated turnaround — 2–3 days from intake to delivery
Watch-outs
- No third-party pharmacy accreditation (no LegitScript, PCAB, ACHC, or NABP)
- BBB rating of B+ (not accredited) with complaints centered on billing and cancellation
- Trustpilot reports of partial refunds and difficulty reaching support
- Compounded only — no FDA-approved Ozempic, Wegovy, Zepbound, or Mounjaro
- Pharmacy partners not named; routes medical and dispensing to third parties
- Also sells testosterone and other wellness products — not GLP-1-focused
- Lowest per-month prices require prepaying for 6- or 12-month plans ($1,050-$1,999 upfront)
Vytora Health
What we like
- All 50 states plus DC, with per-state video-vs-audio compliance disclosed
- Both compounded and brand-name options on one platform — uncommon
- LegitScript Approved and HIPAA compliant
- Pharmacy partners named publicly: Vials Pharmacy (TX) and Greenwich Biosciences
- Operating entity disclosed: Wasef Health, PC (Pinellas Park, FL)
- Competitive monthly pricing ($180 sema / $249 tirz) plus a 3-month bundle saving 17%
- Brand-name Mounjaro and Zepbound available at $1,399/mo for FDA-approved options
Watch-outs
- Brand-name Mounjaro/Zepbound at $1,399/mo is near retail — insured patients may do better via LillyDirect Self Pay ($449-$699/mo)
- Compounded tirzepatide at $249/mo is mid-market, above the $149-199 floor
- Dose tiers aren't broken out — 'all doses included' means low-dose patients pay the same as high-dose
- Initial consultation cost not shown on the public pricing page
- Limited per-prescriber state licensure detail
Our Verdict
TMates is our recommended choice here, particularly for nationwide compounded GLP-1 availability including Puerto Rico. Vytora Health is a solid alternative, especially if you want compounded or brand-name GLP-1 with named pharmacy partners, 50 states — compare the six-dimension breakdown and pricing below to weigh them for your situation.
Choose TMates if…
You want nationwide compounded GLP-1 availability including Puerto Rico and a starting price around $249/mo.
Choose Vytora Health if…
You want compounded or brand-name GLP-1 with named pharmacy partners, 50 states and a starting price around $150/mo.
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Mainstream telehealth GLP-1 access
From $146/mo
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Best overall value
From $135/mo
Get started →Sprout Health
LegitScript-verified compounded GLP-1 via named pharmacies
From $149/mo
Get started →TMates vs Vytora Health: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.