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Amazon One Medical vs TMates

Our featured pick: TMates (affiliate partner). In our scoring, Amazon One Medical scores 8.5 and TMates 6.9 out of 10.

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By Eli Marsden · Founding Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed

Key differences

Price
Amazon One Medical $199/mo for brand-name Wegovy / Ozempic; TMates $249/mo for compounded semaglutide (different medications, so not compared on price)
Coverage
Both serve the same 50 states
Included
Amazon One Medical: clinician visits, shipping (not included: medication, labs); TMates: medication, clinician visits, shipping, coaching

How we compare providers

Amazon One Medical logo

Amazon One Medical

Best for brand-name GLP-1s with published per-dose cash prices and Amazon Pharmacy delivery

Brand-name Wegovy / Ozempic

$199/mo

billed every 4 weeks

Our score 8.5/10

TMates logo

TMates

Affiliate partner

Best for nationwide compounded GLP-1 availability including Puerto Rico

semaglutide

$249/mo

Our score 6.9/10

We may earn a commission if you sign up through these links. Partner status can affect which provider we feature; it never changes a score or a price.

Costs & coverage

Published prices with their terms attached. Yearly figures are modeled from the standing price and billing cadence. A check mark marks the better side, on like-for-like rows only.

Amazon One Medical

TMates

Price

Semaglutide / month

Not listed

$249/mo

Tirzepatide / month

Not listed

$297/mo

Brand Wegovy / Ozempic / month

$199/mo

billed every 4 weeks

Not listed

Brand Zepbound / Mounjaro / month

$299/mo

billed every 4 weeks

Not listed

Brand Wegovy pill / Rybelsus / month

$149/mo

Not listed

Brand Foundayo / month

$149/mo

Not listed

Coverage

State availability

50 states

50 states

Oral option listed

Yes

Not listed

Brand-name access listed

Wegovy / Ozempic, Zepbound / Mounjaro, Wegovy pill / Rybelsus, Foundayo

Not listed

Included in the price

Clinician visits, shipping

Not included: medication, labs

Medication, clinician visits, shipping, coaching

Terms & safety

Price shown

Before intake

Before intake

Lab work

Required

Not disclosed

Cancel anytime

Not disclosed

Yes

Minimum commitment

Not disclosed

None

FDA warning letters

None on record

None on record

Provider facts checked

October 2026

August 2026

Every dose and plan: Amazon One Medical · TMates

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Which fits your priorities?

Only the points where these two differ, from the table above and each provider’s record.

Amazon One Medical logo

Choose Amazon One Medical if…

  • Lists brand-name Wegovy / Ozempic, brand-name Zepbound / Mounjaro and brand-name Wegovy pill / Rybelsus, which TMates doesn't price
  • Publishes cash prices for every GLP-1 dose up front, with manufacturer coupons applied automatically if eligible
  • Brand-name Wegovy, Zepbound and Foundayo prescribed by One Medical clinicians and filled by Amazon Pharmacy

What to weigh up

  • Price doesn't include medication
  • Online On-Demand Care is cash-only for medication; insurance needs scheduled visits near a One Medical office
TMates logo

Choose TMates if…

  • Lists compounded semaglutide and compounded tirzepatide, which Amazon One Medical doesn't price
  • Price includes medication; Amazon One Medical's doesn't
  • All-inclusive monthly price covers medication, consults, nutrition coaching, and 24/7 support — no separate membership fee

What to weigh up

  • No third-party pharmacy accreditation (no LegitScript, PCAB, ACHC, or NABP)
  • BBB rating of B+ (not accredited) with complaints centered on billing and cancellation

Explore the scoring factors

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

Amazon One Medical

8.5/10

Overall

TMates

6.9/10

Value25%

8.5A
vs
B
6.5

Effectiveness25%

8.5A
vs
B
7.5

User Experience15%

8.0A
vs
B
8.0

Trust & Safety15%

8.8A
vs
B
5.3

Accessibility10%

9.5A
vs
B
7.5

Support10%

8.0A
vs
B
6.5

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Compounded GLP-1 access with oral tablet options across 49 states

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7.1

AgelessRx

Longevity-focused GLP-1 care with microdosing and brand-name options

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7.2

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Needle-free compounded semaglutide or tirzepatide tablets

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Amazon One Medical vs TMates: FAQ

Our featured pick is TMates, our affiliate partner. Partner status affects which provider we feature, never the scores: on our six-dimension score, Amazon One Medical is 8.5/10 and TMates 6.9/10, so check the key differences and the breakdown above before you choose.
TMates is an affiliate partner (we may earn a commission on sign-ups through our links); Amazon One Medical is not. Either way, we rank providers editorially with the same scoring framework and disclose every partnership — being a partner does not buy a higher score.
Not at a published price. Amazon One Medical lists brand-name Foundayo, brand-name Wegovy pill / Rybelsus, brand-name Wegovy / Ozempic, brand-name Zepbound / Mounjaro; TMates lists compounded semaglutide, compounded tirzepatide.
Both publish the same list (50 states), so where you live won't decide between them.
Amazon One Medical doesn't state its cancellation terms. TMates: cancel anytime — yes; minimum commitment — None; early-cancellation fee — not disclosed. Check the provider's own terms before you buy.

Key terms, explained

New to GLP-1s? Tap any term for a quick, plain-English definition.

Continue exploring Amazon One Medical and TMates head-to-heads in the same category.

Or see the full category ranking.

Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.