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Amazon One Medical vs Live Vital

An in-depth comparison of two leading GLP-1 Providers

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By Eli Marsden · Founding Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed
Amazon One Medical logo

Amazon One Medical

8.5
★★★★4.3/5

Best for: the most authoritative branded GLP-1 channel with same-day delivery and integrated manufacturer savings

Visit Amazon One Medical
VS
Live Vital logo

Live Vital

7.7
★★★3.9/5

Best for: shoppers who want low-cost, physician-led compounded GLP-1 with peptide and hormone options

Visit Live Vital

Amazon One Medical and Live Vital are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, Live Vital starts lower at $99/mo versus $149/mo, and Live Vital is the option we'd start with for most patients. Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.

Pricing

Amazon One Medical

Foundayo (with insurance + Lilly Savings Card)Brand-name
$25/mo
orforglipron
Foundayo (cash pay)Brand-name
$149/mo
orforglipron

Live Vital

Compounded SemaglutideCompounded
$99/mo
semaglutide

3 month program ($299 total); page live at direct URL but DE-LISTED from the public /treatments catalog, nav, footer, and sitemap

Compounded TirzepatideCompounded
$183/mo
tirzepatide

3 month program ($549 total); page live at direct URL but DE-LISTED from the public /treatments catalog, nav, footer, and sitemap

Retatrutide (triple agonist)Compounded
$299/mo
retatrutide

NEW since our last check; 'Exclusive', prescribed off-label; 'not FDA-approved for weight management and remains in Phase 3 clinical trials'; listed on robots-disallowed /partner-treatments and direct URL only

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What’s included

Amazon One Medical

What the monthly price covers

Medication

Billed separately

Provider visits

Included

Shipping

Included

Lab work

Billed separately

Coaching

Not disclosed

Live Vital

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

Score breakdown

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

Amazon One Medical

8.5/10

Overall

Live Vital

7.7/10

Value25%

8.5A
vs
B
8.5

Effectiveness25%

8.5A
vs
B
7.5

User Experience15%

8.0A
vs
B
6.5

Trust & Safety15%

8.8A
vs
B
7.3

Accessibility10%

9.5A
vs
B
8.5

Support10%

8.0A
vs
B
8.0

Features & Coverage

FeatureAmazon One MedicalLive Vital
Starting Price$149/mo$99/mo
Features6 features7 features
States Available5050
Compounded✓ Yes
Brand Name✓ Yes
FSA/HSA Accepted
FDA WarningsNoneNone

About Amazon One Medical

Amazon One Medical is the unified Amazon GLP-1 channel — One Medical clinicians prescribe FDA-approved Wegovy, Zepbound, and Foundayo (no compounded products), and Amazon Pharmacy fulfills with same-day delivery across roughly 3,000 US cities plus pickup kiosks at select One Medical locations. No prior membership required; insurance and cash pay both accepted. Foundayo launched at $25/month with insurance and the Lilly Savings Card, or $149/month cash pay.

Read our full Amazon One Medical review →

About Live Vital

Live Vital is a physician-led telehealth practice founded by Dr. Patrick Taylor, MD, offering compounded GLP-1 weight loss — semaglutide from $99/mo and tirzepatide from $183/mo, billed as 3-month programs — alongside peptide and hormone therapy. Every plan is doctor-prescribed, filled by a licensed US pharmacy, and shipped to your door, with unlimited care-team messaging and no lock-in. Fully telehealth in all 50 states.

Read our full Live Vital review →

Pros & Cons

Amazon One Medical

What we like

  • As low as $1/day ($25/month) for brand-name Foundayo with insurance and the auto-applied Lilly coupon
  • Same-day delivery in nearly 3,000 US cities at launch, expanding to 4,500 by end of 2026
  • In-office pharmacist kiosks at select One Medical clinics let you walk out with Foundayo in hand
  • Cash-pay $5/day ($149/month) is competitive for the same FDA-approved brand-name product
  • Real-time availability, transparent pricing, and automatic manufacturer coupon at checkout
  • Delivering GLP-1 medications since 2021 — track record on cold-chain logistics

Watch-outs

  • Headline $25/month needs both insurance and the Lilly Savings Card — uninsured pay $149/month
  • Same-day delivery is geographically gated; outside major cities it drops to next-day or slower
  • Pricing is set by manufacturer savings programs and can change at any time
  • No compounded options — brand-name only (Foundayo, Wegovy, Zepbound)
  • Wegovy/Zepbound pricing isn't shown upfront — depends on insurance at the prescribing visit
  • Copays and deductibles still apply to the clinical visit

Live Vital

What we like

  • Physician-led — founded by Dr. Patrick Taylor, MD; all treatments doctor-prescribed via the clinical team
  • Transparent published pricing: semaglutide from $99/mo, tirzepatide from $183/mo (billed as 3-month programs)
  • Every plan includes doctor prescribing, licensed-pharmacy medication, and direct-to-door shipping
  • Unlimited messaging with the care team; cancel or pause anytime with no lock-in
  • Fully telehealth in all 50 states

Watch-outs

  • Sold as 3-month programs (semaglutide $299 / tirzepatide $549 per quarter); 'starting at' rates can rise with dose
  • Doesn't accept insurance (HSA/FSA funds only)
  • Compounding pharmacy isn't named (only 'a licensed US pharmacy')
  • Also a peptide/longevity practice; those peptides are not FDA-approved (the site discloses this)

Our Verdict

Winner: Live Vital

Live Vital is our recommended choice here, particularly for shoppers who want low-cost, physician-led compounded GLP-1 with peptide and hormone options. Amazon One Medical is a solid alternative, especially if you want the most authoritative branded GLP-1 channel with same-day delivery and integrated manufacturer savings — compare the six-dimension breakdown and pricing below to weigh them for your situation.

Choose Amazon One Medical if…

You want the most authoritative branded GLP-1 channel with same-day delivery and integrated manufacturer savings and a starting price around $149/mo.

Choose Live Vital if…

You want shoppers who want low-cost, physician-led compounded GLP-1 with peptide and hormone options and a starting price around $99/mo.

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Compounded semaglutide and tirzepatide at a flat monthly price

7.1

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7.4

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Amazon One Medical vs Live Vital: FAQ

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Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.