Drugs and brands

CagriSema

FDA-approved GLP-1 medications and their generic active ingredients.

Definition

Novo Nordisk's investigational fixed-dose combination of cagrilintide (long-acting amylin analog) plus semaglutide (GLP-1 agonist). REDEFINE 1 reported 20.4% mean weight loss at 68 weeks (22.7% adherent estimand) versus 14.9% with semaglutide alone. Novo has filed an NDA. The result missed Novo's 25% guidance benchmark but still beat semaglutide monotherapy.

CagriSema REDEFINE trial results

Definition curated by Weight Loss Rankings — sourced from FDA labels and peer-reviewed PubMed literature, never AI-generated summaries.

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