Dual agonist
How GLP-1 receptor agonists work — receptors, gastric emptying, and the satiety pathway.
Definition
A medication that activates two receptors at once. Tirzepatide is the GLP-1/GIP dual agonist currently on the market; CagriSema (cagrilintide + semaglutide) and survodutide (GLP-1/glucagon) are in late-stage trials.
GLP-1 pipeline: survodutide, maridebart, ecnoglutide →
Definition curated by Weight Loss Rankings — sourced from FDA labels and peer-reviewed PubMed literature, never AI-generated summaries.
Related terms in Mechanism
- GLP-1 receptor
- GIP receptor
- Gastric emptying
- Food noise
- Triple agonist
- Amylin
- GLP-1 tachyphylaxis
- Non-peptide GLP-1 agonist
- A1C (glycated hemoglobin)
- MASH / MASLD
- TBWL (Total Body Weight Loss)
- C-peptide
- eGFR (estimated glomerular filtration rate)
- Visceral adipose tissue (VAT)
- AHI (apnea-hypopnea index)
- SNAC (oral semaglutide absorption enhancer)
Looking for more depth?
- GLP-1 pipeline: survodutide, maridebart, ecnoglutide
- Browse the full GLP-1 glossary (124 terms across 8 categories)
- Research articles — primary-source deep dives
- Tools and calculators
- Compare GLP-1 telehealth providers