Sesame Care vs TMates
In our scoring, Sesame Care edges ahead overall (8.0 vs 6.9 out of 10).
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Key differences
- Price
- Sesame Care $349/mo for brand-name Wegovy / Ozempic; TMates $249/mo for compounded semaglutide (different medications, so not compared on price)
- Coverage
- TMates 50 states (Sesame Care doesn't publish a state list)
- Included
- Sesame Care: not stated; TMates: medication, clinician visits, shipping, coaching
Sesame Care
Affiliate partnerBest for Brand-name GLP-1s at cash prices, no compounding
Brand-name Wegovy / Ozempic
$349
$199 first month
Our score 8.0/10
TMates
Affiliate partnerBest for nationwide compounded GLP-1 availability including Puerto Rico
semaglutide
$249
Our score 6.9/10
We may earn a commission if you sign up through these links. Partner status can affect which provider we feature; it never changes a score or a price.
Costs & coverage
Published prices with their terms attached. Yearly figures are modeled from the standing price and billing cadence. A check mark marks the better side, on like-for-like rows only.
Sesame Care
TMates
Price
Semaglutide / month
Not listed
$249/mo
Tirzepatide / month
Not listed
$297/mo
Brand Wegovy / Ozempic / month
$349/mo
$199 first month
Not listed
Brand Zepbound / Mounjaro / month
$299/mo
Not listed
Brand Wegovy pill / Rybelsus / month
$149/mo
Not listed
Brand Foundayo / month
$149/mo
Not listed
Coverage
State availability
List not published
50 states
Oral option listed
Yes
Not listed
Brand-name access listed
Wegovy / Ozempic, Zepbound / Mounjaro, Wegovy pill / Rybelsus, Foundayo
Not listed
Included in the price
Not disclosed
Medication, clinician visits, shipping, coaching
Terms & safety
Price shown
Before intake
Before intake
Video visit
Required
Not disclosed
Cancel anytime
Yes
Yes
Minimum commitment
None
None
Early-cancellation fee
None
Not disclosed
FDA warning letters
None on record
None on record
Provider facts checked
August 2026
August 2026
Every dose and plan: Sesame Care · TMates
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Which fits your priorities?
Only the points where these two differ, from the table above and each provider’s record.
Choose Sesame Care if…
- Lists brand-name Wegovy / Ozempic, brand-name Zepbound / Mounjaro and brand-name Wegovy pill / Rybelsus, which TMates doesn't price
- Marketplace transparency — pick a named provider with a displayed price before booking, unlike most opaque telehealth intake
- BBB-accredited and LegitScript-certified
What to weigh up
- No published state list; confirm yours at signup
- Marketplace model means clinician credentials and quality vary provider to provider
Choose TMates if…
- Lists compounded semaglutide and compounded tirzepatide, which Sesame Care doesn't price
- Publishes its full state list (50 states)
- All-inclusive monthly price covers medication, consults, nutrition coaching, and 24/7 support — no separate membership fee
What to weigh up
- No third-party pharmacy accreditation (no LegitScript, PCAB, ACHC, or NABP)
- BBB rating of B+ (not accredited) with complaints centered on billing and cancellation
Explore the scoring factors
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
Sesame Care
8.0/10
TMates
6.9/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
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Collective
The lowest flat medication price if you can absorb an annual membership fee
Read full review →From $59/mo + membership
Get started →From $219/mo
Get started →Found
Compounded GLP-1 with medication included from $169/mo cash, plus insurance help for brand GLP-1s
Read full review →From $169/mo
Get started →Sesame Care vs TMates: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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Or see the full category ranking.
Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.