ShedRx vs TMates
In our scoring, ShedRx edges ahead overall (8.0 vs 6.9 out of 10), and ShedRx costs less for compounded semaglutide (about $1,200 a year less).
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Key differences
- Price
- ShedRx $149/mo vs TMates $249/mo for compounded semaglutide (standing prices, no prepay or separate membership listed · about $1,200 a year less with ShedRx)
- Coverage
- TMates 50 states (ShedRx doesn't publish a state list)
- Included
- ShedRx: medication, clinician visits, coaching; TMates: medication, clinician visits, shipping, coaching
ShedRx
Affiliate partnerBest for compounded GLP-1 as an injection, drops or lozenges, with lower rates on 6- and 12-month plans
semaglutide
$149
Our score 8.0/10
TMates
Affiliate partnerBest for nationwide compounded GLP-1 availability including Puerto Rico
semaglutide
$249
Our score 6.9/10
We may earn a commission if you sign up through these links. Partner status can affect which provider we feature; it never changes a score or a price.
Costs & coverage
Published prices with their terms attached. Yearly figures are modeled from the standing price and billing cadence. A check mark marks the better side, on like-for-like rows only.
ShedRx
TMates
Price
Semaglutide / month
Better on this row: $149/mo
$249/mo
Semaglutide / year (modeled)
Better on this row: $1,788
$2,988
Tirzepatide / month
Better on this row: $199/mo
$297/mo
Tirzepatide / year (modeled)
Better on this row: $2,388
$3,564
Semaglutide (pill or injection) / month
$149/mo
+ separate membership
Not listed
Oral semaglutide / month
$199/mo
Not listed
Brand Foundayo / month
$149/mo
+ separate membership
Not listed
Separate membership required
Yes — not in the listed price
Not stated
Coverage
State availability
List not published
50 states
Oral option listed
Yes
Not listed
Brand-name access listed
Foundayo
Not listed
Included in the price
Medication, clinician visits, coaching
Medication, clinician visits, shipping, coaching
Terms & safety
Price shown
Plan quoted after intake; a price is published
Before intake
Video visit
Not required
Not disclosed
Cancel anytime
Not disclosed
Yes
Minimum commitment
None
None
Refunds
120-day money-back guarantee
Not disclosed
FDA warning letters
None on record
None on record
Provider facts checked
August 2026
August 2026
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Which fits your priorities?
Only the points where these two differ, from the table above and each provider’s record.
Choose ShedRx if…
- About $1,200 a year less than TMates for compounded semaglutide at standing prices
- Lists compounded semaglutide (pill or injection), oral compounded semaglutide and brand-name Foundayo, which TMates doesn't price
- Multiple administration formats
What to weigh up
- No published state list; confirm yours at signup
Choose TMates if…
- Publishes its full state list (50 states)
- All-inclusive monthly price covers medication, consults, nutrition coaching, and 24/7 support — no separate membership fee
- Fast stated turnaround — 2–3 days from intake to delivery
What to weigh up
- About $1,200 a year more than ShedRx for compounded semaglutide
- No third-party pharmacy accreditation (no LegitScript, PCAB, ACHC, or NABP)
Explore the scoring factors
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
ShedRx
8.0/10
TMates
6.9/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Ready to start? Vetted GLP-1 providers
Vetted telehealth providers that prescribe GLP-1 online.
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From $219/mo
Get started →Found
Compounded GLP-1 with medication included from $169/mo cash, plus insurance help for brand GLP-1s
Read full review →From $169/mo
Get started →GobyMeds
No-membership, no-auto-renew compounded GLP-1 orders, from about $99/mo on a 3-month bundle
Read full review →From $169/mo
Get started →ShedRx vs TMates: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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Or see the full category ranking.
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