Sesame Care vs TrimRx
In our scoring, Sesame Care edges ahead overall (8.0 vs 7.7 out of 10), and Sesame Care costs less for brand-name Wegovy / Ozempic (about $14,760 a year less).
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Key differences
- Price
- Sesame Care $349/mo vs TrimRx $1,579/mo for brand-name Wegovy / Ozempic (standing prices, no prepay or separate membership listed · about $14,760 a year less with Sesame Care)
- Included
- Sesame Care: not stated; TrimRx: medication, clinician visits, shipping

Sesame Care
Affiliate partnerBest for Brand-name GLP-1s at cash prices, no compounding
Brand-name Wegovy / Ozempic
$349
$199 first month
Our score 8.0/10
TrimRx
Affiliate partnerAlso prices compounded semaglutide and tirzepatide
semaglutide
$179
$149 first month
Our score 7.7/10
We may earn a commission if you sign up through these links. Partner status can affect which provider we feature; it never changes a score or a price.
Costs & coverage
Published prices with their terms attached. Yearly figures are modeled from the standing price and billing cadence. A check mark marks the better side, on like-for-like rows only.
Sesame Care
TrimRx
Price
Brand Wegovy / Ozempic / month
Better on this row: $349/mo
$199 first month
$1,579/mo
Brand Wegovy / Ozempic / year (modeled)
Better on this row: $4,188
$18,948
Brand Zepbound / Mounjaro / month
Better on this row: $299/mo
$1,249/mo
Brand Zepbound / Mounjaro / year (modeled)
Better on this row: $3,588
$14,988
Semaglutide / month
Not listed
$179/mo
$149 first month
Tirzepatide / month
Not listed
$259/mo
Brand Wegovy pill / Rybelsus / month
$149/mo
Not listed
Brand Foundayo / month
$149/mo
Not listed
Coverage
Oral option listed
Yes
Not listed
Brand-name access listed
Wegovy / Ozempic, Zepbound / Mounjaro, Wegovy pill / Rybelsus, Foundayo
Wegovy / Ozempic, Zepbound / Mounjaro
Included in the price
Not disclosed
Medication, clinician visits, shipping
Terms & safety
Price shown
Before intake
Before intake
Video visit
Required
Not disclosed
Cancel anytime
Yes
Not disclosed
Minimum commitment
None
Not disclosed
Early-cancellation fee
None
Not disclosed
FDA warning letters
None on record
None on record
Provider facts checked
August 2026
August 2026
Every dose and plan: Sesame Care · TrimRx
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Which fits your priorities?
Only the points where these two differ, from the table above and each provider’s record.

Choose Sesame Care if…
- About $14,760 a year less than TrimRx for brand-name Wegovy / Ozempic at standing prices
- Lists brand-name Wegovy pill / Rybelsus and brand-name Foundayo, which TrimRx doesn't price
- Marketplace transparency — pick a named provider with a displayed price before booking, unlike most opaque telehealth intake
What to weigh up
- Marketplace model means clinician credentials and quality vary provider to provider
- Statewide availability can't be listed — it depends on which marketplace providers are licensed in your state
Choose TrimRx if…
- Lists compounded semaglutide and compounded tirzepatide, which Sesame Care doesn't price
- Free shipping with medication delivered to your door monthly — can start as soon as the next day
- Price-stability promise: "switch and keep your current dose," with no advertised mid-program price hikes
What to weigh up
- About $14,760 a year more than Sesame Care for brand-name Wegovy / Ozempic
- Async, questionnaire-based intake — no mandatory video visit with a clinician before prescribing
Explore the scoring factors
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
Sesame Care
8.0/10
TrimRx
7.7/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
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Collective
The lowest flat medication price if you can absorb an annual membership fee
Read full review →From $59/mo + membership
Get started →From $219/mo
Get started →Found
Compounded GLP-1 with medication included from $169/mo cash, plus insurance help for brand GLP-1s
Read full review →From $169/mo
Get started →Sesame Care vs TrimRx: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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Or see the full category ranking.
Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.