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Novi vs NewSelf

An in-depth comparison of two leading GLP-1 Providers

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By Eli Marsden · Founding Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed
Novi logo

Novi

7.3
★★★3.7/5

Best for: transparent all-in compounded GLP-1 pricing

Visit Novi
VS
NewSelf logo

NewSelf

8.3
★★★★4.2/5

Best for: lowest-cost compounded GLP-1 with pharmacy quality transparency

Visit NewSelf

Novi and NewSelf are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, NewSelf starts lower at $100/mo versus $174/mo, and NewSelf edges ahead overall (8.3 vs 7.3 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.

Pricing

Novi

StartingCompounded
$174/mo
semaglutide
StartingCompounded
$283/mo
tirzepatide

NewSelf

Semaglutide+ (best price)Compounded
$100/mo
semaglutide

All dosages same price

Semaglutide+ (regular)Compounded
$135/mo
semaglutide
Tirzepatide+ (best price)Compounded
$144/mo
tirzepatide

All dosages same price

Tirzepatide+ (regular)Compounded
$225/mo
tirzepatide

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What’s included

Novi

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Included

NewSelf

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

Score breakdown

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

Novi

7.3/10

Overall

NewSelf

8.3/10

Value25%

7.0A
vs
B
9.0

Effectiveness25%

8.0A
vs
B
8.0

User Experience15%

7.5A
vs
B
8.0

Trust & Safety15%

6.3A
vs
B
8.3

Accessibility10%

6.0A
vs
B
8.5

Support10%

8.9A
vs
B
7.9

Features & Coverage

FeatureNoviNewSelf
Starting Price$174/mo$100/mo
Features5 features6 features
States AvailableNot disclosed49
Compounded✓ Yes✓ Yes
Brand Name
FSA/HSA Accepted
FDA WarningsNoneNone

About Novi

Novi Health International is a Delaware-based telehealth provider offering compounded semaglutide and tirzepatide with all-in transparent pricing — medication, unlimited clinician support, and free 2-day shipping included. No membership fees or hidden add-ons.

Read our full Novi review →

About NewSelf

NewSelf offers compounded semaglutide+ (with B12/Glycine, from $99.97/mo) and compounded tirzepatide+ (with B6/Glycine, from $144.49/mo). LegitScript certified. Available in 48 states + Puerto Rico. Uses 503A licensed pharmacies with third-party testing.

Read our full NewSelf review →

Pros & Cons

Novi

What we like

  • Transparent all-in monthly pricing — medication, clinician support, and shipping bundled with no hidden fees or membership add-ons
  • Both compounded semaglutide and tirzepatide available
  • Unlimited clinician messaging included at no extra cost
  • Free 2-day shipping on every refill

Watch-outs

  • Compounded only — no FDA-approved Ozempic, Wegovy, Zepbound, or Mounjaro option
  • 3-month minimum commitment is non-refundable per Terms of Service unless a clinician deems treatment medically inappropriate
  • State availability and pharmacy partners not publicly listed — patients learn during intake which states and pharmacies serve them

NewSelf

What we like

  • Semaglutide+ from $99.97/mo — among the lowest prices in the dataset
  • All dosages at the same price — no price escalation as dose increases
  • LegitScript certified with 503A licensed pharmacies
  • Third-party potency, sterility, and endotoxicity testing
  • 48 states + Puerto Rico coverage
  • B12/B6 + Glycine enhanced formulations
  • No membership fees

Watch-outs

  • Not available in Mississippi and Louisiana
  • Compounded only — no brand-name options
  • Site also promotes AI health optimization and longevity (broader platform)

Our Verdict

Winner: NewSelf

NewSelf edges out Novi with a higher overall score of 8.3/10 and is particularly strong for lowest-cost compounded GLP-1 with pharmacy quality transparency. Novi remains a solid alternative, especially if you're looking for transparent all-in compounded GLP-1 pricing.

Choose Novi if…

You want transparent all-in compounded GLP-1 pricing and a starting price around $174/mo.

Choose NewSelf if…

You want lowest-cost compounded GLP-1 with pharmacy quality transparency and a starting price around $100/mo.

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7.7

TrimRx

Best overall value

7.6

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LegitScript-verified compounded GLP-1 via named pharmacies

7.9

Trimi Health

Budget-conscious shoppers

Novi vs NewSelf: FAQ

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Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.