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Novi vs Amazon One Medical

An in-depth comparison of two leading GLP-1 Providers

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By Eli Marsden · Founding Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed
Novi logo

Novi

7.3
★★★3.7/5

Best for: transparent all-in compounded GLP-1 pricing

Visit Novi
VS
Amazon One Medical logo

Amazon One Medical

8.5
★★★★4.3/5

Best for: the most authoritative brand-name GLP-1 channel, with same-day delivery

Visit Amazon One Medical

Novi and Amazon One Medical are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, Novi starts lower at $99/mo versus $149/mo, and Amazon One Medical edges ahead overall (8.5 vs 7.3 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.

Pricing

Novi

StartingCompounded
$99/mo
semaglutide

'Was $299 — Now starting at $99/mo', flat at every dose, with no membership fee and cancel anytime.

StartingCompounded
$133/mo
tirzepatide

'Was $299 — Now starting at $133/mo', on the same flat, no-membership terms.

Amazon One Medical

Foundayo (with insurance + Lilly Savings Card)Brand-name
$25/mo
orforglipron
Foundayo (cash pay)Brand-name
$149/mo
orforglipron

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What’s included

Novi

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Included

Amazon One Medical

What the monthly price covers

Medication

Billed separately

Provider visits

Included

Shipping

Included

Lab work

Billed separately

Coaching

Not disclosed

Score breakdown

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

Novi

7.3/10

Overall

Amazon One Medical

8.5/10

Value25%

7.0A
vs
B
8.5

Effectiveness25%

8.0A
vs
B
8.5

User Experience15%

7.5A
vs
B
8.0

Trust & Safety15%

6.3A
vs
B
8.8

Accessibility10%

6.0A
vs
B
9.5

Support10%

8.9A
vs
B
8.0

Features & Coverage

FeatureNoviAmazon One Medical
Starting Price$99/mo$149/mo
Features5 features6 features
States AvailableNot disclosed50
Compounded✓ Yes
Brand Name✓ Yes
FSA/HSA Accepted
FDA WarningsNoneNone

About Novi

Novi Health International is a Delaware-based telehealth provider offering compounded semaglutide and tirzepatide with all-in transparent pricing — medication, unlimited clinician support, and free 2-day shipping included. No membership fees or hidden add-ons.

Read our full Novi review →

About Amazon One Medical

Amazon One Medical is the unified Amazon GLP-1 channel — One Medical clinicians prescribe FDA-approved Wegovy, Zepbound, and Foundayo (no compounded products), and Amazon Pharmacy fulfills with same-day delivery across roughly 3,000 US cities plus pickup kiosks at select One Medical locations. No prior membership required; insurance and cash pay both accepted. Foundayo launched at $25/month with insurance and the Lilly Savings Card, or $149/month cash pay.

Read our full Amazon One Medical review →

Pros & Cons

Novi

What we like

  • Transparent all-in monthly pricing — medication, clinician support, and shipping bundled with no hidden fees or membership add-ons
  • Both compounded semaglutide and tirzepatide available
  • Unlimited clinician messaging included at no extra cost
  • Free 2-day shipping on every refill

Watch-outs

  • Compounded only — no FDA-approved Ozempic, Wegovy, Zepbound, or Mounjaro option
  • 3-month minimum commitment is non-refundable per Terms of Service unless a clinician deems treatment medically inappropriate
  • State availability and pharmacy partners not publicly listed — patients learn during intake which states and pharmacies serve them

Amazon One Medical

What we like

  • As low as $1/day ($25/month) for brand-name Foundayo with insurance and the auto-applied Lilly coupon
  • Same-day delivery in nearly 3,000 US cities at launch, expanding to 4,500 by end of 2026
  • In-office pharmacist kiosks at select One Medical clinics let you walk out with Foundayo in hand
  • Cash-pay $5/day ($149/month) is competitive for the same FDA-approved brand-name product
  • Real-time availability, transparent pricing, and automatic manufacturer coupon at checkout
  • Delivering GLP-1 medications since 2021 — track record on cold-chain logistics

Watch-outs

  • Headline $25/month needs both insurance and the Lilly Savings Card — uninsured pay $149/month
  • Same-day delivery is geographically gated; outside major cities it drops to next-day or slower
  • Pricing is set by manufacturer savings programs and can change at any time
  • No compounded options — brand-name only (Foundayo, Wegovy, Zepbound)
  • Wegovy/Zepbound pricing isn't shown upfront — depends on insurance at the prescribing visit
  • Copays and deductibles still apply to the clinical visit

Our Verdict

Winner: Amazon One Medical

Amazon One Medical edges out Novi with a higher overall score of 8.5/10 and is particularly strong for the most authoritative brand-name GLP-1 channel, with same-day delivery. Novi remains a solid alternative, especially if you're looking for transparent all-in compounded GLP-1 pricing.

Choose Novi if…

You want transparent all-in compounded GLP-1 pricing and a starting price around $99/mo.

Choose Amazon One Medical if…

You want the most authoritative brand-name GLP-1 channel, with same-day delivery and a starting price around $149/mo.

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6.2

Wellorithm

Compounded GLP-1 access with oral tablet options across 49 states

7.6

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Mainstream telehealth GLP-1 access

7.3

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Compounded GLP-1 with unlimited telehealth visits and free shipping

Novi vs Amazon One Medical: FAQ

Novi is cheaper. Its lowest ongoing monthly cash price is $99/mo, compared with $149/mo for Amazon One Medical. We compare standing (not first-month promo) prices so the figures reflect what you'd actually pay month to month.
Amazon One Medical scores higher overall at 8.5/10 versus 7.3/10, and is particularly strong for the most authoritative brand-name GLP-1 channel, with same-day delivery. That said, Novi is a better fit if you want transparent all-in compounded GLP-1 pricing.
Amazon One Medical lists availability in 50 states, while Novi's state list is not publicly listed.
Neither Novi nor Amazon One Medical is currently an affiliate partner, so we earn no commission from either. We rank all providers editorially using the same six-dimension framework and disclose any commercial relationships.

Key terms, explained

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Continue exploring Novi and Amazon One Medical head-to-heads in the same category.

Or see the full category ranking.

Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.