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Novi vs Vytora Health

An in-depth comparison of two leading GLP-1 Providers

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By Eli Marsden · Founding Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed
Novi logo

Novi

7.3
★★★3.7/5

Best for: transparent all-in compounded GLP-1 pricing

Visit Novi
VS
Vytora Health logo

Vytora Health

8.4
★★★★4.2/5

Best for: compounded or brand-name GLP-1 with named pharmacy partners, 50 states

Visit Vytora Health

Novi and Vytora Health are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, Novi starts lower at $99/mo versus $150/mo, and Vytora Health edges ahead overall (8.4 vs 7.3 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.

Pricing

Novi

StartingCompounded
$99/mo
semaglutide

'Was $299 — Now starting at $99/mo', flat at every dose, with no membership fee and cancel anytime.

StartingCompounded
$133/mo
tirzepatide

'Was $299 — Now starting at $133/mo', on the same flat, no-membership terms.

Vytora Health

All dosesCompounded
$180/mo
semaglutide
3-mo bundle ($450 billed)Compounded
$150/mo
semaglutide
All dosesCompounded
$249/mo
tirzepatide
3-mo bundle ($599 billed)Compounded
$200/mo
tirzepatide
Brand 5/7.5/10/12.5/15 mgBrand-name
$1399/mo
mounjaro
Brand 2.5/5/7.5/10/12.5/15 mgBrand-name
$1399/mo
zepbound

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What’s included

Novi

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Included

Vytora Health

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

Score breakdown

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

Novi

7.3/10

Overall

Vytora Health

8.4/10

Value25%

7.0A
vs
B
8.0

Effectiveness25%

8.0A
vs
B
8.5

User Experience15%

7.5A
vs
B
8.0

Trust & Safety15%

6.3A
vs
B
9.3

Accessibility10%

6.0A
vs
B
8.5

Support10%

8.9A
vs
B
8.4

Features & Coverage

FeatureNoviVytora Health
Starting Price$99/mo$150/mo
Features5 features8 features
States AvailableNot disclosed51
Compounded✓ Yes✓ Yes
Brand Name✓ Yes
FSA/HSA Accepted
FDA WarningsNoneNone

About Novi

Novi Health International is a Delaware-based telehealth provider offering compounded semaglutide and tirzepatide with all-in transparent pricing — medication, unlimited clinician support, and free 2-day shipping included. No membership fees or hidden add-ons.

Read our full Novi review →

About Vytora Health

Vytora Health is a 50-state-plus-DC telehealth platform offering compounded semaglutide and tirzepatide alongside brand-name Mounjaro and Zepbound, plus NAD+ and sermorelin peptides. It names its pharmacy partners publicly — Vials Pharmacy and Greenwich Biosciences — and discloses its operating physician group, uncommon transparency for the category. Compounded semaglutide runs $180/mo ($150 on a 3-month bundle) and tirzepatide $249/mo ($200 bundled).

Read our full Vytora Health review →

Pros & Cons

Novi

What we like

  • Transparent all-in monthly pricing — medication, clinician support, and shipping bundled with no hidden fees or membership add-ons
  • Both compounded semaglutide and tirzepatide available
  • Unlimited clinician messaging included at no extra cost
  • Free 2-day shipping on every refill

Watch-outs

  • Compounded only — no FDA-approved Ozempic, Wegovy, Zepbound, or Mounjaro option
  • 3-month minimum commitment is non-refundable per Terms of Service unless a clinician deems treatment medically inappropriate
  • State availability and pharmacy partners not publicly listed — patients learn during intake which states and pharmacies serve them

Vytora Health

What we like

  • All 50 states plus DC, with per-state video-vs-audio compliance disclosed
  • Both compounded and brand-name options on one platform — uncommon
  • LegitScript Approved and HIPAA compliant
  • Pharmacy partners named publicly: Vials Pharmacy (TX) and Greenwich Biosciences
  • Operating entity disclosed: Wasef Health, PC (Pinellas Park, FL)
  • Competitive monthly pricing ($180 sema / $249 tirz) plus a 3-month bundle saving 17%
  • Brand-name Mounjaro and Zepbound available at $1,399/mo for FDA-approved options

Watch-outs

  • Brand-name Mounjaro/Zepbound at $1,399/mo is near retail — insured patients may do better via LillyDirect Self Pay ($449-$699/mo)
  • Compounded tirzepatide at $249/mo is mid-market, above the $149-199 floor
  • Dose tiers aren't broken out — 'all doses included' means low-dose patients pay the same as high-dose
  • Initial consultation cost not shown on the public pricing page
  • Limited per-prescriber state licensure detail

Our Verdict

Winner: Vytora Health

Vytora Health edges out Novi with a higher overall score of 8.4/10 and is particularly strong for compounded or brand-name GLP-1 with named pharmacy partners, 50 states. Novi remains a solid alternative, especially if you're looking for transparent all-in compounded GLP-1 pricing.

Choose Novi if…

You want transparent all-in compounded GLP-1 pricing and a starting price around $99/mo.

Choose Vytora Health if…

You want compounded or brand-name GLP-1 with named pharmacy partners, 50 states and a starting price around $150/mo.

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8.1

GobyMeds

Budget-conscious shoppers

7.6

RNK Health

Compounded GLP-1 alongside NAD+, peptide and longevity add-ons

6.2

Wellorithm

Compounded GLP-1 access with oral tablet options across 49 states

Novi vs Vytora Health: FAQ

Novi is cheaper. Its lowest ongoing monthly cash price is $99/mo, compared with $150/mo for Vytora Health. We compare standing (not first-month promo) prices so the figures reflect what you'd actually pay month to month.
Vytora Health scores higher overall at 8.4/10 versus 7.3/10, and is particularly strong for compounded or brand-name GLP-1 with named pharmacy partners, 50 states. That said, Novi is a better fit if you want transparent all-in compounded GLP-1 pricing.
Vytora Health lists availability in 51 states, while Novi's state list is not publicly listed.
Neither Novi nor Vytora Health is currently an affiliate partner, so we earn no commission from either. We rank all providers editorially using the same six-dimension framework and disclose any commercial relationships.
For Semaglutide, Novi is cheaper at $99/mo versus $150/mo at Vytora Health.

Key terms, explained

New to GLP-1s? Tap any term for a quick, plain-English definition.

Continue exploring Novi and Vytora Health head-to-heads in the same category.

Or see the full category ranking.

Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.