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CoreAge Rx vs Sesame Care

An in-depth comparison of two leading GLP-1 Providers

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By Eli Marsden · Founding Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed
CoreAge Rx logo

CoreAge Rx

8.3
★★★★4.2/5

Best for: best overall value

Visit CoreAge Rx
VS
Sesame Care logo

Sesame Care

8.0
★★★★4/5

Best for: Brand-name GLP-1s at cash prices, no compounding

Visit Sesame Care

CoreAge Rx and Sesame Care are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, CoreAge Rx starts lower at $99/mo versus $149/mo, and CoreAge Rx edges ahead overall (8.3 vs 8.0 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.

Pricing

CoreAge Rx

Injectable, monthly auto-refill (flat across all dosages)Compounded
$99/mo
semaglutide

Re-verified 2026-08-05: homepage + Preventive Longevity section both show "Semaglutide — Starting at $99/mo", "Same price at every dose"; supersedes stale tiered pricing captured 2026-06-05.

Injectable, monthly auto-refill (flat across all dosages)Compounded
$149/mo
tirzepatide

Re-verified 2026-08-05: homepage GLP-1 hero + Preventive Longevity section both show "Tirzepatide — Starting at $149/mo", "Same price at every dose"; supersedes stale tiered pricing captured 2026-06-05.

Sesame Care

Annual planCompounded
$59/mo
clinical care only — medication billed separately

Month-to-Month $99/mo, 3-Month $39/mo, 6-Month $49/mo, Annual $59/mo; includes video visits, unlimited messaging, follow-ups, labs (savings $60/3mo, $180/6mo, $480/yr)

all doses 0.25-2.4mgCompounded
$349$199/mo
Save 43% right now
semaglutide (wegovy)

$199/mo first two months, new self-pay patients, lowest doses (0.25/0.5mg) only; FAQ terms state offer valid through 2026-06-30 but $199 still advertised on 2026-07-14

1.5mg / 4mgCompounded · oral
$149/mo
semaglutide (wegovy)

low doses

9mg / 25mgCompounded · oral
$299/mo
semaglutide (wegovy)

high doses; maintenance dose $50/mo cheaper than Wegovy injection

0.25mg / 0.5mg / 1mgCompounded
$349$199/mo
Save 43% right now
semaglutide (ozempic)

NEW published pricing: $199 first two months (same new-self-pay intro terms as Wegovy); 2mg is $499/mo

2.5mgCompounded
$299/mo
tirzepatide (zepbound)

$399/mo for 5mg; $449/mo for 7.5mg, 10mg, 12.5mg, 15mg — unchanged vs stored

2.5mgCompounded
$299/mo
tirzepatide (zepbound)

$399/mo 5mg, $499/mo 7.5mg, $699/mo 10-15mg (program page shows $398/$698 — Sesame's own pages disagree by $1)

starts atCompounded
$1086/mo
tirzepatide (zepbound)

NEW row on program page: 'Zepbound® Tirzepatide Starts at $1,086 per / mo' (retail-channel pen, distinct from LillyDirect KwikPen)

0.8mgCompounded · oral
$149/mo
orforglipron (foundayo)

$199/mo at 2.5mg, $299 at 5.5mg and 9mg, $349 at 14.5mg and 17.2mg.

as low asCompounded
$25/mo
semaglutide or tirzepatide (with commercial insurance)

'Price with insurance: as low as $25 per / mo.' — copay varies by plan/PA outcome

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What’s included

CoreAge Rx

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

Sesame Care

Inclusions not disclosed.

Score breakdown

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

CoreAge Rx

8.3/10

Overall

Sesame Care

8.0/10

Value25%

8.5A
vs
B
7.5

Effectiveness25%

8.5A
vs
B
9.0

User Experience15%

8.5A
vs
B
8.0

Trust & Safety15%

7.8A
vs
B
8.0

Accessibility10%

8.0A
vs
B
6.5

Support10%

8.4A
vs
B
8.0

Features & Coverage

FeatureCoreAge RxSesame Care
Starting Price$99/mo$149/mo
Features6 features8 features
States Available50Not disclosed
Compounded✓ Yes✓ Yes
Brand Name
FSA/HSA Accepted
FDA WarningsNoneNone

About CoreAge Rx

CoreAge Rx offers LegitScript-verified compounded semaglutide and tirzepatide with free 2-day shipping to all 50 states. Backed by licensed physicians and 24/7 support, it delivers the most competitive pricing in the compounded GLP-1 space.

Read our full CoreAge Rx review →

About Sesame Care

Sesame is a transparent-pricing telehealth marketplace that connects patients directly with independent provider practices — distinct from the stocked-formulary model of most weight-loss platforms. Its weight-loss vertical is brand-name only (no compounding): a $39–$99/month subscription covers clinical care, while medication is billed separately at cash-pay rates, including Zepbound from $299 via LillyDirect and a Wegovy self-pay promo at $199/month.

Read our full Sesame Care review →

Pros & Cons

CoreAge Rx

What we like

  • LegitScript certified — rigorous pharmacy standards
  • Free 2-day shipping nationwide
  • Both semaglutide and tirzepatide available
  • Lowest per-month pricing in the compounded segment
  • 24/7 support team
  • All 50 states covered

Watch-outs

  • Compounded only — no brand-name Ozempic or Wegovy
  • Newer brand with fewer independent reviews than legacy players

Sesame Care

What we like

  • Marketplace transparency — pick a named provider with a displayed price before booking, unlike most opaque telehealth intake
  • BBB-accredited and LegitScript-verified
  • LillyDirect partnership unlocks Zepbound vial and KwikPen cash pricing matching Lilly's lowest direct rates ($299 at lowest dose)
  • Wegovy self-pay promo ($199/mo for first two months, lowest dose, new self-pay) — among the lowest brand-Wegovy cash prices
  • Honest subscription scope — clinical care only, medication billed separately
  • Stocks both Wegovy pill ($149/mo low doses) and Foundayo orforglipron alongside injectables
  • Lab work included in subscription for 41 states (excludes AZ/HI/ND/NJ/NY/OK/RI/SD/WY)
  • Insurance route ($25/mo possible) is viable — providers assist with prior authorization

Watch-outs

  • Marketplace model means clinician credentials and quality vary provider to provider
  • Statewide availability can't be listed — it depends on which marketplace providers are licensed in your state
  • No in-house pharmacy — fulfillment splits across LillyDirect, NovoCare, and your retail pharmacy
  • Restrictive refunds — full refund only if you cancel 3+ hours before the first visit; no refund once the visit occurs
  • Subscription commitment required — no genuine pay-per-visit option for weight loss
  • Wegovy $199/mo promo applies only to new self-pay patients at the lowest dose; $349/mo after month 2
  • Wegovy pill high doses ($299/mo for 9mg/25mg) cost about 2x the low-dose price as you titrate up
  • Zepbound KwikPen high doses ($699/mo for 10–15mg) approach Lilly's list price

Our Verdict

Winner: CoreAge Rx

CoreAge Rx edges out Sesame Care with a higher overall score of 8.3/10 and is particularly strong for best overall value. Sesame Care remains a solid alternative, especially if you're looking for Brand-name GLP-1s at cash prices, no compounding.

Choose CoreAge Rx if…

You want best overall value and a starting price around $99/mo.

Choose Sesame Care if…

You want Brand-name GLP-1s at cash prices, no compounding and a starting price around $149/mo.

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6.4

Direct Meds

Listed for disclosure only — see its FDA warning and BBB complaints first

7.8

Care Bare Rx

LGBTQ+-inclusive compounded GLP-1 telehealth

8.2

Enhance MD

Lab-monitored compounded GLP-1 with mandatory video visit

CoreAge Rx vs Sesame Care: FAQ

CoreAge Rx is cheaper. Its lowest ongoing monthly cash price is $99/mo, compared with $149/mo for Sesame Care. We compare standing (not first-month promo) prices so the figures reflect what you'd actually pay month to month.
CoreAge Rx scores higher overall at 8.3/10 versus 8.0/10, and is particularly strong for best overall value. That said, Sesame Care is a better fit if you want Brand-name GLP-1s at cash prices, no compounding.
CoreAge Rx lists availability in 50 states, while Sesame Care's state list is not publicly listed.
Both CoreAge Rx and Sesame Care are affiliate partners, meaning we may earn a commission if you sign up through our links. Our scores are assigned editorially using the same six-dimension framework for every provider — partnership never changes a score. We disclose every commercial relationship.

Key terms, explained

New to GLP-1s? Tap any term for a quick, plain-English definition.

Continue exploring CoreAge Rx and Sesame Care head-to-heads in the same category.

Or see the full category ranking.

Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.