Signos vs CoreAge Rx
An in-depth comparison of two leading GLP-1 Providers
WeightLossRankings.org is reader-supported. When you buy through links on our site, we may earn an affiliate commission. Learn more
Signos
Best for: Pairing compounded GLP-1 (semaglutide) with an FDA-cleared continuous glucose monitor and app
Visit Signos →
Signos and CoreAge Rx are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, CoreAge Rx starts lower at $149/mo versus $199/mo, and CoreAge Rx edges ahead overall (8.3 vs 7.5 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.
Pricing
Signos
Signos+ GLP-1 bundle (tirzepatide OR semaglutide) from $199/mo; includes CGM system
CoreAge Rx
Get alerted when GLP-1 prices drop
Join the GLP-1 price-watch list — we re-verify 390+ providers' prices on their own sites and email you when tracked prices move.
What’s included
Signos
What the monthly price covers
Medication
Included
Provider visits
Not disclosed
Shipping
Included
Lab work
Not disclosed
Coaching
Not disclosed
CoreAge Rx
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Included
Lab work
Not disclosed
Coaching
Not disclosed
Score breakdown
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
Signos
7.5/10
CoreAge Rx
8.3/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Features & Coverage
| Feature | Signos | CoreAge Rx |
|---|---|---|
| Starting Price | $199/mo | ✓$149/mo |
| Features | ✓8 features | 6 features |
| States Available | Not disclosed | 50 |
| Compounded | ✓ Yes | ✓ Yes |
| Brand Name | — | — |
| FSA/HSA Accepted | ✓ Yes | — |
| FDA Warnings | None | None |
About Signos
Signos (Signos+) is a metabolic-health platform that bundles clinician-prescribed compounded GLP-1 (semaglutide) with an FDA-cleared continuous glucose monitor (CGM) and app — pairing the medication with real-time glucose data and coaching so users understand and sustain their weight loss. The program starts at $199/mo on a 6-month plan, includes free shipping, and is HSA/FSA eligible. It is pitched as the same price as medication alone, with the CGM added.
Read our full Signos review →About CoreAge Rx
CoreAge Rx offers LegitScript-verified compounded semaglutide and tirzepatide with free 2-day shipping to all 50 states. Backed by licensed physicians and 24/7 support, it delivers the most competitive pricing in the compounded GLP-1 space.
Read our full CoreAge Rx review →Pros & Cons
Signos
What we like
- Bundles compounded GLP-1 (semaglutide) with an FDA-cleared CGM and app — glucose-guided weight loss, not just medication
- Starting at $199/mo on a 6-month program, with the CGM included at no extra cost
- Free rapid shipping; HSA/FSA eligible
- Real-time glucose insights and app coaching to help sustain results after GLP-1
Watch-outs
- Compounded GLP-1s are not FDA-approved finished products
- Headline price is a 6-month-program rate, not month-to-month
- Only semaglutide is shown in the program; tirzepatide availability is not confirmed
- Compounding pharmacy partner and state availability are not published on the landing page
CoreAge Rx
What we like
- LegitScript certified — rigorous pharmacy standards
- Free 2-day shipping nationwide
- Both semaglutide and tirzepatide available
- Lowest per-month pricing in the compounded segment
- 24/7 support team
- All 50 states covered
Watch-outs
- Compounded only — no brand-name Ozempic or Wegovy
- Newer brand with fewer independent reviews than legacy players
Our Verdict
CoreAge Rx edges out Signos with a higher overall score of 8.3/10 and is particularly strong for best overall value. Signos remains a solid alternative, especially if you're looking for Pairing compounded GLP-1 (semaglutide) with an FDA-cleared continuous glucose monitor and app.
Choose Signos if…
You want Pairing compounded GLP-1 (semaglutide) with an FDA-cleared continuous glucose monitor and app and a starting price around $199/mo.
Choose CoreAge Rx if…
You want best overall value and a starting price around $149/mo.
Ready to start? Vetted GLP-1 providers
Vetted telehealth providers that prescribe GLP-1 online.
No insurance needed · vetted by our editors
WeightLossRankings.org is reader-supported. When you buy through links on our site, we may earn an affiliate commission. Learn more
MEDVi
Patients who want the option to switch between compounded and brand-name GLP-1 through one provider
From $99/mo
Get started →Liv Body
Compounded GLP-1 paired with a muscle-preservation supplement stack
From $179/mo
Get started →DudeMeds
Men seeking no-fee GLP-1 access with oral and injectable options
From $175/mo
Get started →Signos vs CoreAge Rx: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
Related comparisons
Continue exploring Signos and CoreAge Rx head-to-heads in the same category.
- Signos vs Amazon One Medical
- Signos vs Vytora Health
- Signos vs EverSlim
- CoreAge Rx vs Found
- CoreAge Rx vs NewSelf
- CoreAge Rx vs Elara Health and Wellness
Or see the full category ranking.
Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.