SkinnyRx vs TMates
In our scoring, SkinnyRx edges ahead overall (7.6 vs 6.9 out of 10), and SkinnyRx costs less for compounded semaglutide (about $1,197 a year less).
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Key differences
- Price
- SkinnyRx $149.25/mo vs TMates $249/mo for compounded semaglutide (standing prices, no prepay or separate membership listed · about $1,197 a year less with SkinnyRx)
- Coverage
- TMates 50 states (SkinnyRx doesn't publish a state list)
- Included
- SkinnyRx: medication, clinician visits, shipping; TMates: medication, clinician visits, shipping, coaching
- Safety
- FDA warning letters on record: SkinnyRx 1, TMates none
SkinnyRx
Affiliate partnerBest for compounded semaglutide or tirzepatide with the consult and free overnight shipping in one price
semaglutide
$149.25
Our score 7.6/10
TMates
Affiliate partnerBest for nationwide compounded GLP-1 availability including Puerto Rico
semaglutide
$249
Our score 6.9/10
We may earn a commission if you sign up through these links. Partner status can affect which provider we feature; it never changes a score or a price.
Costs & coverage
Published prices with their terms attached. Yearly figures are modeled from the standing price and billing cadence. A check mark marks the better side, on like-for-like rows only.
SkinnyRx
TMates
Price
Semaglutide / month
Better on this row: $149.25/mo
$249/mo
Semaglutide / year (modeled)
Better on this row: $1,791
$2,988
Tirzepatide / month
Better on this row: $224.25/mo
$297/mo
Tirzepatide / year (modeled)
Better on this row: $2,691
$3,564
Oral semaglutide / month
$199/mo
Not listed
Brand Wegovy / Ozempic / month
$1,400/mo
Not listed
Brand Zepbound / Mounjaro / month
$1,400/mo
Not listed
Coverage
State availability
List not published
50 states
Oral option listed
Yes
Not listed
Brand-name access listed
Wegovy / Ozempic, Zepbound / Mounjaro
Not listed
Included in the price
Medication, clinician visits, shipping
Medication, clinician visits, shipping, coaching
Terms & safety
Price shown
Plan quoted after intake; a price is published
Before intake
Cancel anytime
Not disclosed
Yes
Minimum commitment
Not disclosed
None
Refunds
90-day money-back guarantee
Not disclosed
FDA warning letters
1 warning letter
Better on this row: None on record
Provider facts checked
August 2026
August 2026
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Which fits your priorities?
Only the points where these two differ, from the table above and each provider’s record.
Choose SkinnyRx if…
- About $1,197 a year less than TMates for compounded semaglutide at standing prices
- Lists oral compounded semaglutide, brand-name Wegovy / Ozempic and brand-name Zepbound / Mounjaro, which TMates doesn't price
- Licensed US clinicians on every prescription
What to weigh up
- 1 FDA warning letter on record
- No published state list; confirm yours at signup
Choose TMates if…
- Publishes its full state list (50 states)
- No FDA warning letters on record (SkinnyRx has 1)
- All-inclusive monthly price covers medication, consults, nutrition coaching, and 24/7 support — no separate membership fee
What to weigh up
- About $1,197 a year more than SkinnyRx for compounded semaglutide
- No third-party pharmacy accreditation (no LegitScript, PCAB, ACHC, or NABP)
Explore the scoring factors
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
SkinnyRx
7.6/10
TMates
6.9/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
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From $139/mo
Get started →From $299/mo
Get started →SkinnyRx
Compounded semaglutide or tirzepatide with the consult and free overnight shipping in one price
Read full review →From $149.25/mo
Get started →SkinnyRx vs TMates: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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Or see the full category ranking.
Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.