PlexusDx vs TrimRx
In our scoring, TrimRx edges ahead overall (7.7 vs 7.0 out of 10).
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Key differences
- Price
- PlexusDx $129/mo no prepay listed; TrimRx $179/mo no prepay listed (compounded semaglutide · not like-for-like, so neither is marked cheaper)
- Coverage
- PlexusDx 50 states (TrimRx doesn't publish a state list)
- Included
- PlexusDx: medication, clinician visits; TrimRx: medication, clinician visits, shipping
PlexusDx
Affiliate partnerBest for nationwide compounded GLP-1 with optional genetic-test personalization
semaglutide
$129
microdose plan
Our score 7.0/10
TrimRx
Affiliate partnerBest for best overall value
semaglutide
$179
$149 first month · starting dose
Our score 7.7/10
We may earn a commission if you sign up through these links. Partner status can affect which provider we feature; it never changes a score or a price.
Costs & coverage
Published prices with their terms attached. Yearly figures are modeled from the standing price and billing cadence. A check mark marks the better side, on like-for-like rows only.
PlexusDx
TrimRx
Price
Semaglutide / month
$129/mo
microdose plan
$179/mo
$149 first month · starting dose
Semaglutide / year (modeled)
$1,548
$2,148
Tirzepatide / month
$249/mo
starting dose
$259/mo
starting dose
Tirzepatide / year (modeled)
$2,988
$3,108
Brand Wegovy / Ozempic / month
Not listed
$1,579/mo
starting dose
Brand Zepbound / Mounjaro / month
Not listed
$1,249/mo
starting dose
Coverage
State availability
50 states
List not published
Brand-name access listed
Not listed
Wegovy / Ozempic, Zepbound / Mounjaro
Included in the price
Medication, clinician visits
Medication, clinician visits, shipping
Terms & safety
Price shown
Before intake
Before intake
FDA warning letters
None on record
None on record
Provider facts checked
August 2026
August 2026
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Which fits your priorities?
Only the points where these two differ, from the table above and each provider’s record.
Choose PlexusDx if…
- Publishes its full state list (50 states)
- Optional Precision Peptide genetic panel adds a personalization angle
- Independent clinician review via state-licensed telehealth platform
What to weigh up
- Compounded medications only; no FDA-approved brand options
- Specific compounding pharmacies not named
Choose TrimRx if…
- Lists brand-name Wegovy / Ozempic and brand-name Zepbound / Mounjaro, which PlexusDx doesn't price
- Free shipping with medication delivered to your door monthly — can start as soon as the next day
- Price-stability promise: "switch and keep your current dose," with no advertised mid-program price hikes
What to weigh up
- No published state list; confirm yours at signup
- Async, questionnaire-based intake — no mandatory video visit with a clinician before prescribing
Explore the scoring factors
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
PlexusDx
7.0/10
TrimRx
7.7/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Ready to start? Vetted GLP-1 providers
Vetted telehealth providers that prescribe GLP-1 online.
No insurance needed · vetted by our editors
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ShedRx
Compounded GLP-1 as an injection, drops or lozenges, with lower rates on 6- and 12-month plans
Read full review →From $299/mo (after intro offer)
Get started →bmiMD
One flat compounded GLP-1 price at every dose: semaglutide $159/mo month to month, $119/mo on a 12-month plan
Read full review →From $159/mo
Get started →altRX
Low-cost compounded GLP-1s with brand-name Zepbound, Wegovy and Ozempic as options
Read full review →From $89/mo
Get started →PlexusDx vs TrimRx: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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- PlexusDx vs CoreAge Rx
- TrimRx vs ShedRx
- TrimRx vs Amazon One Medical
- TrimRx vs Vytora Health
Or see the full category ranking, or alternatives to PlexusDx and TrimRx.
Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.