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CoreAge Rx vs PlexusDx

An in-depth comparison of two leading GLP-1 Providers

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By Eli Marsden · Founding Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed
CoreAge Rx logo

CoreAge Rx

8.3
★★★★4.2/5

Best for: best overall value

Visit CoreAge Rx
VS
PlexusDx logo

PlexusDx

7.0
★★★3.5/5

Best for: Shoppers wanting nationwide compounded GLP-1 with optional genetic-test personalization

Visit PlexusDx

CoreAge Rx and PlexusDx are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, PlexusDx starts lower at $129/mo versus $149/mo, and CoreAge Rx edges ahead overall (8.3 vs 7.0 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.

Pricing

CoreAge Rx

0.25mgCompounded
$149/mo
semaglutide
0.5mgCompounded
$199/mo
semaglutide
1mgCompounded
$249/mo
semaglutide
1.7mgCompounded
$299/mo
semaglutide
2.5mgCompounded
$349/mo
tirzepatide

PlexusDx

Microdose GLP-1 monthlyCompounded
$129/mo
semaglutide
Compounded semaglutide startingCompounded
$149/mo
semaglutide
Compounded tirzepatide startingCompounded
$249/mo
tirzepatide

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What’s included

CoreAge Rx

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

PlexusDx

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Not disclosed

Lab work

Not disclosed

Coaching

Not disclosed

Score breakdown

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

CoreAge Rx

8.3/10

Overall

PlexusDx

7.0/10

Value25%

8.5A
vs
B
7.0

Effectiveness25%

8.5A
vs
B
7.0

User Experience15%

8.5A
vs
B
7.0

Trust & Safety15%

7.8A
vs
B
6.8

Accessibility10%

8.0A
vs
B
7.5

Support10%

8.4A
vs
B
6.5

Features & Coverage

FeatureCoreAge RxPlexusDx
Starting Price$149/mo$129/mo
Features6 features8 features
States Available5050
Compounded✓ Yes✓ Yes
Brand Name
FSA/HSA Accepted
FDA WarningsNoneNone

About CoreAge Rx

CoreAge Rx offers LegitScript-verified compounded semaglutide and tirzepatide with free 2-day shipping to all 50 states. Backed by licensed physicians and 24/7 support, it delivers the most competitive pricing in the compounded GLP-1 space.

Read our full CoreAge Rx review →

About PlexusDx

PlexusDx (plexusdx.com) is a US GLP-1 telehealth platform offering compounded weight-loss medications with licensed providers in all 50 states. Programs include a microdose GLP-1 from $129/month, compounded semaglutide from $149/month, compounded tirzepatide from $249/month, and a combination GLP-Squared protocol. An independent US-licensed clinician reviews each patient via a state-licensed telehealth platform, and medications come from state-licensed pharmacies. PlexusDx is distinctive for an optional Precision Peptide genetic test (151 insights) discounted to $99 after a first order.

Read our full PlexusDx review →

Pros & Cons

CoreAge Rx

What we like

  • LegitScript certified — rigorous pharmacy standards
  • Free 2-day shipping nationwide
  • Both semaglutide and tirzepatide available
  • Lowest per-month pricing in the compounded segment
  • 24/7 support team
  • All 50 states covered

Watch-outs

  • Compounded only — no brand-name Ozempic or Wegovy
  • Newer brand with fewer independent reviews than legacy players

PlexusDx

What we like

  • Licensed providers available in all 50 states
  • Range of options including low-cost microdose GLP-1 from $129/mo
  • Optional Precision Peptide genetic panel adds a personalization angle
  • Independent clinician review via state-licensed telehealth platform
  • Compounded medications from state-licensed pharmacies

Watch-outs

  • Compounded medications only; no FDA-approved brand options
  • Specific compounding pharmacies not named
  • Genetic-panel upsell may not add clinical value for everyone
  • Tirzepatide pricing from $249/mo is higher than budget rivals
  • No insurance accepted

Our Verdict

Winner: CoreAge Rx

CoreAge Rx edges out PlexusDx with a higher overall score of 8.3/10 and is particularly strong for best overall value. PlexusDx remains a solid alternative, especially if you're looking for Shoppers wanting nationwide compounded GLP-1 with optional genetic-test personalization.

Choose CoreAge Rx if…

You want best overall value and a starting price around $149/mo.

Choose PlexusDx if…

You want Shoppers wanting nationwide compounded GLP-1 with optional genetic-test personalization and a starting price around $129/mo.

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CoreAge Rx vs PlexusDx: FAQ

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