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Amazon One Medical vs MangoRx

Our featured pick: MangoRx (affiliate partner). In our scoring, Amazon One Medical scores 8.5 and MangoRx 5.5 out of 10.

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By Eli Marsden · Founding Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed

Key differences

Price
Amazon One Medical $199/mo for brand-name Wegovy / Ozempic; MangoRx $299/mo for oral compounded semaglutide (different medications, so not compared on price)
Coverage
Amazon One Medical 50 states (MangoRx doesn't publish a state list)
Included
Amazon One Medical: clinician visits, shipping (not included: medication, labs); MangoRx: medication, clinician visits

How we compare providers

Amazon One Medical logo

Amazon One Medical

Best for brand-name GLP-1s with published per-dose cash prices and Amazon Pharmacy delivery

Brand-name Wegovy / Ozempic

$199/mo

billed every 4 weeks

Our score 8.5/10

MangoRx logo

MangoRx

Affiliate partner

Best for men's-health shoppers who want oral compounded semaglutide at one flat price across doses

Oral compounded semaglutide

$299/mo

$269.10 first month

Our score 5.5/10

We may earn a commission if you sign up through these links. Partner status can affect which provider we feature; it never changes a score or a price.

Costs & coverage

Published prices with their terms attached. Yearly figures are modeled from the standing price and billing cadence. A check mark marks the better side, on like-for-like rows only.

Amazon One Medical

MangoRx

Price

Oral semaglutide / month

Not listed

$299/mo

$269.10 first month

Brand Wegovy / Ozempic / month

$199/mo

billed every 4 weeks

Not listed

Brand Zepbound / Mounjaro / month

$299/mo

billed every 4 weeks

Not listed

Brand Wegovy pill / Rybelsus / month

$149/mo

Not listed

Brand Foundayo / month

$149/mo

Not listed

Coverage

State availability

50 states

List not published

Oral option listed

Yes

Yes

Brand-name access listed

Wegovy / Ozempic, Zepbound / Mounjaro, Wegovy pill / Rybelsus, Foundayo

Not listed

Included in the price

Clinician visits, shipping

Not included: medication, labs

Medication, clinician visits

Terms & safety

Price shown

Before intake

Plan quoted after intake; a price is published

Lab work

Required

Not disclosed

Minimum commitment

Not disclosed

None

Refunds

Not disclosed

Full refund if declined, else all sales final

FDA warning letters

None on record

None on record

Provider facts checked

October 2026

August 2026

Every dose and plan: Amazon One Medical · MangoRx

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Which fits your priorities?

Only the points where these two differ, from the table above and each provider’s record.

Amazon One Medical logo

Choose Amazon One Medical if…

  • Lists brand-name Wegovy / Ozempic, brand-name Zepbound / Mounjaro and brand-name Wegovy pill / Rybelsus, which MangoRx doesn't price
  • Publishes its full state list (50 states)
  • Publishes cash prices for every GLP-1 dose up front, with manufacturer coupons applied automatically if eligible

What to weigh up

  • Price doesn't include medication
  • Online On-Demand Care is cash-only for medication; insurance needs scheduled visits near a One Medical office
MangoRx logo

Choose MangoRx if…

  • Lists oral compounded semaglutide, which Amazon One Medical doesn't price
  • Price includes medication; Amazon One Medical's doesn't
  • Men's-health telehealth that bundles GLP-1, TRT, ED, and hair care under one provider

What to weigh up

  • No published state list; confirm yours at signup
  • GLP-1 formulary, pricing tiers, states served, and pharmacy partners not yet confirmed

Explore the scoring factors

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

Amazon One Medical

8.5/10

Overall

MangoRx

5.5/10

Value25%

8.5A
vs
B
4.0

Effectiveness25%

8.5A
vs
B
5.5

User Experience15%

8.0A
vs
B
7.5

Trust & Safety15%

8.8A
vs
B
6.0

Accessibility10%

9.5A
vs
B
5.0

Support10%

8.0A
vs
B
6.0

Ready to start? Vetted GLP-1 providers

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7.4

MadeMed

Compounded GLP-1 in both injection and oral forms

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From $219/mo

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8.3

Found

Compounded GLP-1 with medication included from $169/mo cash, plus insurance help for brand GLP-1s

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From $169/mo

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7.9

GobyMeds

No-membership, no-auto-renew compounded GLP-1 orders, from about $99/mo on a 3-month bundle

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From $169/mo

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Amazon One Medical vs MangoRx: FAQ

Our featured pick is MangoRx, our affiliate partner. Partner status affects which provider we feature, never the scores: on our six-dimension score, Amazon One Medical is 8.5/10 and MangoRx 5.5/10, so check the key differences and the breakdown above before you choose.
MangoRx is an affiliate partner (we may earn a commission on sign-ups through our links); Amazon One Medical is not. Either way, we rank providers editorially with the same scoring framework and disclose every partnership — being a partner does not buy a higher score.
Not at a published price. Amazon One Medical lists brand-name Foundayo, brand-name Wegovy pill / Rybelsus, brand-name Wegovy / Ozempic, brand-name Zepbound / Mounjaro; MangoRx lists oral compounded semaglutide.
Amazon One Medical publishes 50 states. MangoRx doesn't publish a state list. Where a list isn't published, confirm your state during sign-up before paying.
Amazon One Medical doesn't state its cancellation terms. MangoRx: cancel anytime — not disclosed; minimum commitment — None; early-cancellation fee — not disclosed. Check the provider's own terms before you buy.

Key terms, explained

New to GLP-1s? Tap any term for a quick, plain-English definition.

Continue exploring Amazon One Medical and MangoRx head-to-heads in the same category.

Or see the full category ranking.

Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.