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HumeCare+ vs ShedRx

In our scoring, ShedRx edges ahead overall (8.0 vs 7.2 out of 10), and ShedRx costs less for compounded semaglutide (about $600 a year less).

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By Eli Marsden · Founding Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed

Key differences

Price
ShedRx $149/mo vs HumeCare+ $199/mo for compounded semaglutide (standing prices, no prepay or separate membership listed · about $600 a year less with ShedRx)
Coverage
HumeCare+ 46 states + DC (ShedRx doesn't publish a state list)
Included
HumeCare+: medication, clinician visits; ShedRx: medication, clinician visits, coaching

How we compare providers

HumeCare+ logo

HumeCare+

Affiliate partner

Best for GLP-1 weight loss with real-time body-composition tracking to protect muscle

semaglutide

$199/mo

Our score 7.2/10

ShedRx logo

ShedRx

Affiliate partner

Best for compounded GLP-1 as an injection, drops or lozenges, with lower rates on 6- and 12-month plans

semaglutide

$149/mo

Our score 8.0/10

We may earn a commission if you sign up through these links. Partner status can affect which provider we feature; it never changes a score or a price.

Costs & coverage

Published prices with their terms attached. Yearly figures are modeled from the standing price and billing cadence. A check mark marks the better side, on like-for-like rows only.

HumeCare+

ShedRx

Price

Semaglutide / month

$199/mo

Better on this row: $149/mo

Semaglutide / year (modeled)

$2,388

Better on this row: $1,788

Tirzepatide / month

$299/mo

Better on this row: $199/mo

Tirzepatide / year (modeled)

$3,588

Better on this row: $2,388

Oral semaglutide / month

$199/mo

$199/mo

Oral semaglutide / year (modeled)

$2,388

$2,388

Semaglutide (pill or injection) / month

Not listed

$149/mo

+ separate membership

Brand Foundayo / month

Not listed

$149/mo

+ separate membership

Separate membership required

Not stated

Yes — not in the listed price

Coverage

State availability

46 states + DC

List not published

Oral option listed

Yes

Yes

Brand-name access listed

Not listed

Foundayo

Included in the price

Medication, clinician visits

Medication, clinician visits, coaching

Terms & safety

Price shown

Plan quoted after intake; a price is published

Plan quoted after intake; a price is published

Video visit

Not disclosed

Not required

Cancel anytime

Yes

Not disclosed

Minimum commitment

None

None

Refunds

Terms: if the physician finds you ineligible the plan is refunded automatically and the Hume Pod must be returned. Otherwise there are no pro-rated refunds, and cancellation must be at least 48 hours before the renewal date. A clinical consultation fee assessed at enrollment and at each refill is carved out as non-refundable; its amount is not published.

120-day money-back guarantee

Early-cancellation fee

None

Not disclosed

FDA warning letters

None on record

None on record

Provider facts checked

August 2026

August 2026

Every dose and plan: HumeCare+ · ShedRx

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Which fits your priorities?

Only the points where these two differ, from the table above and each provider’s record.

HumeCare+ logo

Choose HumeCare+ if…

  • Publishes its full state list (46 states + DC)
  • Pairs compounded semaglutide with continuous body-composition tracking (lose fat, preserve muscle)
  • Includes a Hume Pod body-composition device at no extra cost

What to weigh up

  • About $600 a year more than ShedRx for compounded semaglutide
  • No price appears on the marketing site; you must finish the intake quiz and give your name before one is quoted
ShedRx logo

Choose ShedRx if…

  • About $600 a year less than HumeCare+ for compounded semaglutide at standing prices
  • Lists compounded semaglutide (pill or injection) and brand-name Foundayo, which HumeCare+ doesn't price
  • Multiple administration formats

What to weigh up

  • No published state list; confirm yours at signup

Explore the scoring factors

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

HumeCare+

7.2/10

Overall

ShedRx

8.0/10

Value25%

7.5A
vs
B
7.5

Effectiveness25%

7.0A
vs
B
9.0

User Experience15%

7.5A
vs
B
8.0

Trust & Safety15%

6.8A
vs
B
7.3

Accessibility10%

7.0A
vs
B
7.5

Support10%

7.4A
vs
B
8.0

Ready to start? Vetted GLP-1 providers

Vetted telehealth providers that prescribe GLP-1 online.

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6.2

Wellorithm

Compounded GLP-1 access with oral tablet options across 49 states

Read full review →

From $247/mo

Get started →
7.1

AgelessRx

Longevity-focused GLP-1 care with microdosing and brand-name options

Read full review →

From $139/mo

Get started →
7.2

Willow

Needle-free compounded semaglutide or tirzepatide tablets

Read full review →

From $299/mo

Get started →

HumeCare+ vs ShedRx: FAQ

For compounded semaglutide, ShedRx costs less: about $600 less a year at the standing price, with no prepay or separate membership listed (not a first-month promo). See Costs & coverage above for each medication side by side.
ShedRx scores higher overall at 8.0/10 versus 7.2/10, and is particularly strong for compounded GLP-1 as an injection, drops or lozenges, with lower rates on 6- and 12-month plans. That said, HumeCare+ is a better fit if you want GLP-1 weight loss with real-time body-composition tracking to protect muscle.
Both HumeCare+ and ShedRx are affiliate partners, meaning we may earn a commission if you sign up through our links. Our scores are assigned editorially using the same six-dimension framework for every provider — partnership never changes a score. We disclose every commercial relationship.
HumeCare+: $199, about $2,388 a year. ShedRx: $149, about $1,788 a year. ShedRx costs about $600 less a year at these prices.
HumeCare+ publishes 46 states + DC. ShedRx doesn't publish a state list. Where a list isn't published, confirm your state during sign-up before paying.
HumeCare+: cancel anytime — yes; minimum commitment — None; early-cancellation fee — none. ShedRx: cancel anytime — not disclosed; minimum commitment — None; early-cancellation fee — not disclosed. Check the provider's own terms before you buy.

Key terms, explained

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Continue exploring HumeCare+ and ShedRx head-to-heads in the same category.

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