HumeCare+ vs SkinnyRx
In our scoring, SkinnyRx edges ahead overall (7.6 vs 7.2 out of 10), and SkinnyRx costs less for compounded semaglutide (about $597 a year less).
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Key differences
- Price
- SkinnyRx $149.25/mo vs HumeCare+ $199/mo for compounded semaglutide (standing prices, no prepay or separate membership listed · about $597 a year less with SkinnyRx)
- Coverage
- HumeCare+ 46 states + DC (SkinnyRx doesn't publish a state list)
- Included
- HumeCare+: medication, clinician visits; SkinnyRx: medication, clinician visits, shipping
- Safety
- FDA warning letters on record: HumeCare+ none, SkinnyRx 1
HumeCare+
Affiliate partnerBest for GLP-1 weight loss with real-time body-composition tracking to protect muscle
semaglutide
$199
Our score 7.2/10

SkinnyRx
Affiliate partnerBest for compounded semaglutide or tirzepatide with the consult and free overnight shipping in one price
semaglutide
$149.25
Our score 7.6/10
We may earn a commission if you sign up through these links. Partner status can affect which provider we feature; it never changes a score or a price.
Costs & coverage
Published prices with their terms attached. Yearly figures are modeled from the standing price and billing cadence. A check mark marks the better side, on like-for-like rows only.
HumeCare+
SkinnyRx
Price
Semaglutide / month
$199/mo
Better on this row: $149.25/mo
Semaglutide / year (modeled)
$2,388
Better on this row: $1,791
Tirzepatide / month
$299/mo
Better on this row: $224.25/mo
Tirzepatide / year (modeled)
$3,588
Better on this row: $2,691
Oral semaglutide / month
$199/mo
$199/mo
Oral semaglutide / year (modeled)
$2,388
$2,388
Brand Wegovy / Ozempic / month
Not listed
$1,400/mo
Brand Zepbound / Mounjaro / month
Not listed
$1,400/mo
Coverage
State availability
46 states + DC
List not published
Oral option listed
Yes
Yes
Brand-name access listed
Not listed
Wegovy / Ozempic, Zepbound / Mounjaro
Included in the price
Medication, clinician visits
Medication, clinician visits, shipping
Terms & safety
Price shown
Plan quoted after intake; a price is published
Plan quoted after intake; a price is published
Cancel anytime
Yes
Not disclosed
Minimum commitment
None
Not disclosed
Refunds
Terms: if the physician finds you ineligible the plan is refunded automatically and the Hume Pod must be returned. Otherwise there are no pro-rated refunds, and cancellation must be at least 48 hours before the renewal date. A clinical consultation fee assessed at enrollment and at each refill is carved out as non-refundable; its amount is not published.
90-day money-back guarantee
Early-cancellation fee
None
Not disclosed
FDA warning letters
Better on this row: None on record
1 warning letter
Provider facts checked
August 2026
August 2026
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Which fits your priorities?
Only the points where these two differ, from the table above and each provider’s record.
Choose HumeCare+ if…
- Publishes its full state list (46 states + DC)
- No FDA warning letters on record (SkinnyRx has 1)
- Pairs compounded semaglutide with continuous body-composition tracking (lose fat, preserve muscle)
What to weigh up
- About $597 a year more than SkinnyRx for compounded semaglutide
- No price appears on the marketing site; you must finish the intake quiz and give your name before one is quoted

Choose SkinnyRx if…
- About $597 a year less than HumeCare+ for compounded semaglutide at standing prices
- Lists brand-name Wegovy / Ozempic and brand-name Zepbound / Mounjaro, which HumeCare+ doesn't price
- Licensed US clinicians on every prescription
What to weigh up
- 1 FDA warning letter on record
- No published state list; confirm yours at signup
Explore the scoring factors
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
HumeCare+
7.2/10
SkinnyRx
7.6/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Ready to start? Vetted GLP-1 providers
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GobyMeds
No-membership, no-auto-renew compounded GLP-1 orders, from about $99/mo on a 3-month bundle
Read full review →From $169/mo
Get started →Ivim Health
Compounded GLP-1 with weekly provider check-ins and health coaches, under a required monthly membership
Read full review →From $65/mo + membership
Get started →From $247/mo
Get started →HumeCare+ vs SkinnyRx: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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Or see the full category ranking.
Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.