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EverSlim vs Signos

An in-depth comparison of two leading GLP-1 Providers

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By Eli Marsden · Founding Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed

EverSlim

8.3
★★★★4.2/5

Best for: budget-minded patients wanting flat-price compounded glp-1 care shipped nationwide

Visit EverSlim
VS
Signos logo

Signos

7.5
★★★3.8/5

Best for: Pairing compounded GLP-1 (semaglutide) with an FDA-cleared continuous glucose monitor and app

Visit Signos

EverSlim and Signos are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, EverSlim starts lower at $127/mo versus $199/mo, and EverSlim edges ahead overall (8.3 vs 7.5 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.

Pricing

EverSlim

All doses (flat)Compounded
$127/mo
semaglutide

Flat monthly price; medication, provider visit, and shipping included

All doses (flat)Compounded
$183/mo
tirzepatide

Flat monthly price; dual-action GLP-1 and GIP

Signos

6-month programCompounded
$199/mo
semaglutide
StartingCompounded
$199/mo
tirzepatide

Signos+ GLP-1 bundle (tirzepatide OR semaglutide) from $199/mo; includes CGM system

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What’s included

EverSlim

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

Signos

What the monthly price covers

Medication

Included

Provider visits

Not disclosed

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

Score breakdown

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

EverSlim

8.3/10

Overall

Signos

7.5/10

Value25%

8.5A
vs
B
7.5

Effectiveness25%

8.0A
vs
B
7.5

User Experience15%

8.5A
vs
B
7.5

Trust & Safety15%

7.8A
vs
B
7.8

Accessibility10%

9.5A
vs
B
7.0

Support10%

7.5A
vs
B
7.5

Features & Coverage

FeatureEverSlimSignos
Starting Price$127/mo$199/mo
Features8 features8 features
States Available51Not disclosed
Compounded✓ Yes✓ Yes
Brand Name
FSA/HSA Accepted✓ Yes
FDA WarningsNoneNone

About EverSlim

EverSlim is a US telehealth program offering doctor-prescribed, compounded GLP-1 weight-loss medication delivered to your door. It provides compounded semaglutide from 127 dollars a month and compounded tirzepatide from 183 dollars a month, a flat monthly price that includes the provider visit, prescription, and free shipping, with no insurance or membership required. Care is delivered by licensed US providers through the DrTelx medical group and filled by named LegitScript-approved US compounding pharmacies. Available in all 50 states and DC. Compounded meds are not FDA-approved.

Read our full EverSlim review →

About Signos

Signos (Signos+) is a metabolic-health platform that bundles clinician-prescribed compounded GLP-1 (semaglutide) with an FDA-cleared continuous glucose monitor (CGM) and app — pairing the medication with real-time glucose data and coaching so users understand and sustain their weight loss. The program starts at $199/mo on a 6-month plan, includes free shipping, and is HSA/FSA eligible. It is pitched as the same price as medication alone, with the CGM added.

Read our full Signos review →

Pros & Cons

EverSlim

What we like

  • Transparent flat pricing from 127 dollars a month for compounded semaglutide; medication, provider visit, and shipping included with no insurance.
  • Names its pharmacy partners (EPIQ Scripts, Foothills, Emerald) and DrTelx medical group; LegitScript-approved and NABP-accredited.
  • Available in all 50 states and DC, with asynchronous care in 44 states and live-visit access in the rest.
  • Offers both semaglutide and tirzepatide, plus care-team messaging between visits.

Watch-outs

  • Compounded medications are not FDA-approved, and no brand-name Wegovy, Ozempic, or Zepbound options are offered.
  • Site discloses that some imagery and content may be AI-generated and some ad figures are actors, not real clinicians.
  • Newer brand with limited independent, third-party review history.

Signos

What we like

  • Bundles compounded GLP-1 (semaglutide) with an FDA-cleared CGM and app — glucose-guided weight loss, not just medication
  • Starting at $199/mo on a 6-month program, with the CGM included at no extra cost
  • Free rapid shipping; HSA/FSA eligible
  • Real-time glucose insights and app coaching to help sustain results after GLP-1

Watch-outs

  • Compounded GLP-1s are not FDA-approved finished products
  • Headline price is a 6-month-program rate, not month-to-month
  • Only semaglutide is shown in the program; tirzepatide availability is not confirmed
  • Compounding pharmacy partner and state availability are not published on the landing page

Our Verdict

Winner: EverSlim

EverSlim edges out Signos with a higher overall score of 8.3/10 and is particularly strong for budget-minded patients wanting flat-price compounded glp-1 care shipped nationwide. Signos remains a solid alternative, especially if you're looking for Pairing compounded GLP-1 (semaglutide) with an FDA-cleared continuous glucose monitor and app.

Choose EverSlim if…

You want budget-minded patients wanting flat-price compounded glp-1 care shipped nationwide and a starting price around $127/mo.

Choose Signos if…

You want Pairing compounded GLP-1 (semaglutide) with an FDA-cleared continuous glucose monitor and app and a starting price around $199/mo.

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EverSlim vs Signos: FAQ

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