Amazon One Medical vs MyFastRx
An in-depth comparison of two leading GLP-1 Providers
WeightLossRankings.org is reader-supported. When you buy through links on our site, we may earn an affiliate commission. Learn more
Amazon One Medical
Best for: the most authoritative brand-name GLP-1 channel, with same-day delivery
Visit Amazon One Medical →
MyFastRx
Best for: 12-month upfront billing for the lowest compounded-GLP-1 monthly rate.
Visit MyFastRx →Amazon One Medical and MyFastRx are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, MyFastRx starts lower at $99/mo versus $149/mo, and Amazon One Medical edges ahead overall (8.5 vs 7.0 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.
Pricing
Amazon One Medical
MyFastRx
Get alerted when GLP-1 prices drop
Join the GLP-1 price-watch list — we re-verify 500+ providers' prices on their own sites and email you when tracked prices move.
What’s included
Amazon One Medical
What the monthly price covers
Medication
Billed separately
Provider visits
Included
Shipping
Included
Lab work
Billed separately
Coaching
Not disclosed
MyFastRx
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Included
Lab work
Not disclosed
Coaching
Not disclosed
Score breakdown
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
Amazon One Medical
8.5/10
MyFastRx
7.0/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Features & Coverage
| Feature | Amazon One Medical | MyFastRx |
|---|---|---|
| Starting Price | $149/mo | ✓$99/mo |
| Features | 6 features | ✓8 features |
| States Available | 50 | 50 |
| Compounded | — | ✓ Yes |
| Brand Name | ✓ Yes | — |
| FSA/HSA Accepted | — | — |
| FDA Warnings | None | None |
About Amazon One Medical
Amazon One Medical is the unified Amazon GLP-1 channel — One Medical clinicians prescribe FDA-approved Wegovy, Zepbound, and Foundayo (no compounded products), and Amazon Pharmacy fulfills with same-day delivery across roughly 3,000 US cities plus pickup kiosks at select One Medical locations. No prior membership required; insurance and cash pay both accepted. Foundayo launched at $25/month with insurance and the Lilly Savings Card, or $149/month cash pay.
Read our full Amazon One Medical review →About MyFastRx
MyFastRx is a cash-pay compounded-GLP-1 platform built around fast approval and discounted multi-month bundles. Compounded semaglutide runs $169/mo standard, dropping to $99/mo on a 12-month prepay; tirzepatide is $249/mo standard, down to $149/mo on 12 months — all doses priced the same with a SAVE70 first-month promo. It accepts no insurance and ships nationwide; LegitScript-listed and HIPAA-compliant.
Read our full MyFastRx review →Pros & Cons
Amazon One Medical
What we like
- As low as $1/day ($25/month) for brand-name Foundayo with insurance and the auto-applied Lilly coupon
- Same-day delivery in nearly 3,000 US cities at launch, expanding to 4,500 by end of 2026
- In-office pharmacist kiosks at select One Medical clinics let you walk out with Foundayo in hand
- Cash-pay $5/day ($149/month) is competitive for the same FDA-approved brand-name product
- Real-time availability, transparent pricing, and automatic manufacturer coupon at checkout
- Delivering GLP-1 medications since 2021 — track record on cold-chain logistics
Watch-outs
- Headline $25/month needs both insurance and the Lilly Savings Card — uninsured pay $149/month
- Same-day delivery is geographically gated; outside major cities it drops to next-day or slower
- Pricing is set by manufacturer savings programs and can change at any time
- No compounded options — brand-name only (Foundayo, Wegovy, Zepbound)
- Wegovy/Zepbound pricing isn't shown upfront — depends on insurance at the prescribing visit
- Copays and deductibles still apply to the clinical visit
MyFastRx
What we like
- Aggressive 12-month bundle pricing — $99/mo semaglutide, $149/mo tirzepatide
- LegitScript certified
- All doses priced the same — no cost escalation as you titrate up
- First-month promo discount lowers the trial barrier
Watch-outs
- States served not disclosed — only 'multiple states' / 'licensed U.S. providers'
- Corporate address and medical director not published
- Pharmacy partner not named — only 'state-licensed pharmacies'
- Cash-pay only — no insurance billing
- Bundle savings require a large upfront commitment (12 months billed at once)
Our Verdict
Amazon One Medical edges out MyFastRx with a higher overall score of 8.5/10 and is particularly strong for the most authoritative brand-name GLP-1 channel, with same-day delivery. MyFastRx remains a solid alternative, especially if you're looking for 12-month upfront billing for the lowest compounded-GLP-1 monthly rate..
Choose Amazon One Medical if…
You want the most authoritative brand-name GLP-1 channel, with same-day delivery and a starting price around $149/mo.
Choose MyFastRx if…
You want 12-month upfront billing for the lowest compounded-GLP-1 monthly rate. and a starting price around $99/mo.
Ready to start? Vetted GLP-1 providers
Vetted telehealth providers that prescribe GLP-1 online.
No insurance needed · vetted by our editors
WeightLossRankings.org is reader-supported. When you buy through links on our site, we may earn an affiliate commission. Learn more
TrimRx
Best overall value
From $149/mo
Get started →Sprout Health
LegitScript-verified compounded GLP-1 via named pharmacies
From $149/mo
Get started →PeterMD
Men wanting flat-priced compounded GLP-1 with TRT or peptides
From $215.67/mo
Get started →Amazon One Medical vs MyFastRx: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
Related comparisons
Continue exploring Amazon One Medical and MyFastRx head-to-heads in the same category.
- Amazon One Medical vs Vytora Health
- Amazon One Medical vs Collective
- Amazon One Medical vs CoreAge Rx
- MyFastRx vs EverSlim
- MyFastRx vs Found
- MyFastRx vs NewSelf
Or see the full category ranking.
Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.