Actin vs Amazon One Medical
In our scoring, Amazon One Medical edges ahead overall (8.5 vs 7.0 out of 10).
WeightLossRankings.org is reader-supported. When you buy through links on our site, we may earn an affiliate commission. Learn more
Key differences
- Price
- Actin $169/mo for compounded semaglutide; Amazon One Medical $199/mo for brand-name Wegovy / Ozempic (different medications, so not compared on price)
- Coverage
- Amazon One Medical 50 states (Actin doesn't publish a state list)
- Included
- Actin: not stated; Amazon One Medical: clinician visits, shipping (not included: medication, labs)
Actin
Best for affordable compounded semaglutide with B12 enhancement
semaglutide
$169
Our score 7.0/10
Amazon One Medical
Best for brand-name GLP-1s with published per-dose cash prices and Amazon Pharmacy delivery
Brand-name Wegovy / Ozempic
$199
billed every 4 weeks
Our score 8.5/10
We may earn a commission if you sign up through these links. Partner status can affect which provider we feature; it never changes a score or a price.
Costs & coverage
Published prices with their terms attached. Yearly figures are modeled from the standing price and billing cadence. A check mark marks the better side, on like-for-like rows only.
Actin
Amazon One Medical
Price
Semaglutide / month
$169/mo
Not listed
Tirzepatide / month
$269/mo
Not listed
Brand Wegovy / Ozempic / month
Not listed
$199/mo
billed every 4 weeks
Brand Zepbound / Mounjaro / month
Not listed
$299/mo
billed every 4 weeks
Brand Wegovy pill / Rybelsus / month
Not listed
$149/mo
Brand Foundayo / month
Not listed
$149/mo
Coverage
State availability
List not published
50 states
Oral option listed
Not listed
Yes
Brand-name access listed
Not listed
Wegovy / Ozempic, Zepbound / Mounjaro, Wegovy pill / Rybelsus, Foundayo
Included in the price
Not disclosed
Clinician visits, shipping
Not included: medication, labs
Terms & safety
Price shown
Plan quoted after intake; a price is published
Before intake
Lab work
Better on this row: Not required
Required
Video visit
Not required
Not disclosed
Minimum commitment
None
Not disclosed
FDA warning letters
None on record
None on record
Provider facts checked
August 2026
October 2026
Every dose and plan: Actin · Amazon One Medical
Get alerted when GLP-1 prices drop
Join the GLP-1 price-watch list — we re-verify 540+ providers' prices on their own sites and email you when tracked prices move.
Which fits your priorities?
Only the points where these two differ, from the table above and each provider’s record.
Choose Actin if…
- Lists compounded semaglutide and compounded tirzepatide, which Amazon One Medical doesn't price
- No lab work required to start
- Semaglutide paired with B12 for added energy support
What to weigh up
- No published state list; confirm yours at signup
- Semaglutide only — no tirzepatide or liraglutide
Choose Amazon One Medical if…
- Lists brand-name Wegovy / Ozempic, brand-name Zepbound / Mounjaro and brand-name Wegovy pill / Rybelsus, which Actin doesn't price
- Publishes its full state list (50 states)
- Publishes cash prices for every GLP-1 dose up front, with manufacturer coupons applied automatically if eligible
What to weigh up
- Lab work required to start
- Online On-Demand Care is cash-only for medication; insurance needs scheduled visits near a One Medical office
Explore the scoring factors
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
Actin
7.0/10
Amazon One Medical
8.5/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Ready to start? Vetted GLP-1 providers
Vetted telehealth providers that prescribe GLP-1 online.
No insurance needed · vetted by our editors
WeightLossRankings.org is reader-supported. When you buy through links on our site, we may earn an affiliate commission. Learn more
Found
Compounded GLP-1 with medication included from $169/mo cash, plus insurance help for brand GLP-1s
Read full review →From $169/mo
Get started →GobyMeds
No-membership, no-auto-renew compounded GLP-1 orders, from about $99/mo on a 3-month bundle
Read full review →From $169/mo
Get started →Ivim Health
Compounded GLP-1 with weekly provider check-ins and health coaches, under a required monthly membership
Read full review →From $65/mo + membership
Get started →Actin vs Amazon One Medical: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
Related comparisons
Continue exploring Actin and Amazon One Medical head-to-heads in the same category.
- Actin vs Vytora Health
- Amazon One Medical vs Vytora Health
- Amazon One Medical vs CoreAge Rx
- Amazon One Medical vs Collective
Or see the full category ranking.
Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.