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Actin vs Vytora Health

An in-depth comparison of two leading GLP-1 Providers

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By Eli Marsden · Founding Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed
Actin logo

Actin

7.0
★★★3.5/5

Best for: affordable compounded semaglutide with B12 enhancement

Visit Actin
VS
Vytora Health logo

Vytora Health

8.4
★★★★4.2/5

Best for: compounded or brand-name GLP-1 with named pharmacy partners, 50 states

Visit Vytora Health

Actin and Vytora Health are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, Vytora Health starts lower at $150/mo versus $169/mo, and Vytora Health edges ahead overall (8.4 vs 7.0 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.

Pricing

Actin

Compounded GLP-1 (semaglutide + B12)Compounded
$169/mo
semaglutide

Month-to-month. Actin prints all three cadences on the product page: 1-Month $169, 3-Month $143, 6-Month $116, flat at every dose.

Compounded tirzepatide (with B12 or glycine) — month-to-monthCompounded
$269/mo
tirzepatide

ADDED 2026-08-15 — we had no tirzepatide row although Actin sells it. Ladder on the product page: 1-Month $269, 3-Month $209, 6-Month $166, flat at every dose.

Vytora Health

All dosesCompounded
$180/mo
semaglutide
3-mo bundle ($450 billed)Compounded
$150/mo
semaglutide
All dosesCompounded
$249/mo
tirzepatide
3-mo bundle ($599 billed)Compounded
$200/mo
tirzepatide
Brand 5/7.5/10/12.5/15 mgBrand-name
$1399/mo
mounjaro
Brand 2.5/5/7.5/10/12.5/15 mgBrand-name
$1399/mo
zepbound

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What’s included

Actin

Inclusions not disclosed.

Vytora Health

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

Score breakdown

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

Actin

7.0/10

Overall

Vytora Health

8.4/10

Value25%

7.0A
vs
B
8.0

Effectiveness25%

7.0A
vs
B
8.5

User Experience15%

7.0A
vs
B
8.0

Trust & Safety15%

7.3A
vs
B
9.3

Accessibility10%

7.0A
vs
B
8.5

Support10%

7.0A
vs
B
8.4

Features & Coverage

FeatureActinVytora Health
Starting Price$169/mo$150/mo
Features3 features8 features
States AvailableNot disclosed51
Compounded✓ Yes✓ Yes
Brand Name✓ Yes
FSA/HSA Accepted
FDA WarningsNoneNone

About Actin

Actin sells compounded semaglutide at $169/month and compounded tirzepatide at $269/month month-to-month, falling to $116 and $166 on a six-month plan, flat at every dose with no membership fee. It also offers a GLP-1 microdose at $149/month alongside longevity, sexual-wellness and hair treatments, and states plainly that it is not a compounding pharmacy itself.

Read our full Actin review →

About Vytora Health

Vytora Health is a 50-state-plus-DC telehealth platform offering compounded semaglutide and tirzepatide alongside brand-name Mounjaro and Zepbound, plus NAD+ and sermorelin peptides. It names its pharmacy partners publicly — Vials Pharmacy and Greenwich Biosciences — and discloses its operating physician group, uncommon transparency for the category. Compounded semaglutide runs $180/mo ($150 on a 3-month bundle) and tirzepatide $249/mo ($200 bundled).

Read our full Vytora Health review →

Pros & Cons

Actin

What we like

  • Semaglutide paired with B12 for added energy support
  • Transparent pricing — exact cost shown upfront with no hidden fees
  • Competitive pricing from $116/mo on the 6-month plan ($169/mo month-to-month)

Watch-outs

  • Semaglutide only — no tirzepatide or liraglutide
  • No visible LegitScript or PCAB accreditation
  • States served not disclosed
  • Broad platform spanning hormones, sexual wellness, and hair health

Vytora Health

What we like

  • All 50 states plus DC, with per-state video-vs-audio compliance disclosed
  • Both compounded and brand-name options on one platform — uncommon
  • LegitScript Approved and HIPAA compliant
  • Pharmacy partners named publicly: Vials Pharmacy (TX) and Greenwich Biosciences
  • Operating entity disclosed: Wasef Health, PC (Pinellas Park, FL)
  • Competitive monthly pricing ($180 sema / $249 tirz) plus a 3-month bundle saving 17%
  • Brand-name Mounjaro and Zepbound available at $1,399/mo for FDA-approved options

Watch-outs

  • Brand-name Mounjaro/Zepbound at $1,399/mo is near retail — insured patients may do better via LillyDirect Self Pay ($449-$699/mo)
  • Compounded tirzepatide at $249/mo is mid-market, above the $149-199 floor
  • Dose tiers aren't broken out — 'all doses included' means low-dose patients pay the same as high-dose
  • Initial consultation cost not shown on the public pricing page
  • Limited per-prescriber state licensure detail

Our Verdict

Winner: Vytora Health

Vytora Health edges out Actin with a higher overall score of 8.4/10 and is particularly strong for compounded or brand-name GLP-1 with named pharmacy partners, 50 states. Actin remains a solid alternative, especially if you're looking for affordable compounded semaglutide with B12 enhancement.

Choose Actin if…

You want affordable compounded semaglutide with B12 enhancement and a starting price around $169/mo.

Choose Vytora Health if…

You want compounded or brand-name GLP-1 with named pharmacy partners, 50 states and a starting price around $150/mo.

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Actin vs Vytora Health: FAQ

Vytora Health is cheaper. Its lowest ongoing monthly cash price is $150/mo, compared with $169/mo for Actin. We compare standing (not first-month promo) prices so the figures reflect what you'd actually pay month to month.
Vytora Health scores higher overall at 8.4/10 versus 7.0/10, and is particularly strong for compounded or brand-name GLP-1 with named pharmacy partners, 50 states. That said, Actin is a better fit if you want affordable compounded semaglutide with B12 enhancement.
Vytora Health lists availability in 51 states, while Actin's state list is not publicly listed.
Neither Actin nor Vytora Health is currently an affiliate partner, so we earn no commission from either. We rank all providers editorially using the same six-dimension framework and disclose any commercial relationships.
For Semaglutide, Vytora Health is cheaper at $150/mo versus $169/mo at Actin.

Key terms, explained

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Continue exploring Actin and Vytora Health head-to-heads in the same category.

Or see the full category ranking.

Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.