Medsol RX vs Vytora Health
In our scoring, Vytora Health edges ahead overall (8.4 vs 7.4 out of 10), and Vytora Health costs less for compounded tirzepatide (about $120 a year less).
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Key differences
- Price
- Vytora Health $249/mo vs Medsol RX $259/mo for compounded tirzepatide (standing prices, no prepay or separate membership listed · about $120 a year less with Vytora Health)
- Coverage
- Medsol RX 50 states; Vytora Health 50 states + DC (only Vytora Health: District of Columbia)
- Included
- Medsol RX: medication, clinician visits, shipping, coaching; Vytora Health: medication, clinician visits, shipping

Medsol RX
Best for flexible, HSA/FSA-eligible compounded GLP-1 plans with a care coach
semaglutide
$149
microdose plan
Our score 7.4/10

Vytora Health
Best for compounded or brand-name GLP-1 with named pharmacy partners, 50 states
semaglutide
$179
Our score 8.4/10
We may earn a commission if you sign up through these links. Partner status can affect which provider we feature; it never changes a score or a price.
Costs & coverage
Published prices with their terms attached. Yearly figures are modeled from the standing price and billing cadence. A check mark marks the better side, on like-for-like rows only.
Medsol RX
Vytora Health
Price
Semaglutide / month
$149/mo
microdose plan
$179/mo
Semaglutide / year (modeled)
$1,788
$2,148
Tirzepatide / month
$259/mo
$239 first month
Better on this row: $249/mo
Tirzepatide / year (modeled)
$3,108
Better on this row: $2,988
Brand Zepbound / Mounjaro / month
$1,399/mo
$1,399/mo
Brand Zepbound / Mounjaro / year (modeled)
$16,788
$16,788
Tirzepatide (pill or injection) / month
$149/mo
microdose plan
Not listed
Oral semaglutide / month
$179/mo
Not listed
Brand Wegovy / Ozempic / month
$1,229/mo
Not listed
Coverage
State availability
50 states
50 states + DC
Oral option listed
Yes
Not listed
Brand-name access listed
Zepbound / Mounjaro, Wegovy / Ozempic
Zepbound / Mounjaro
Included in the price
Medication, clinician visits, shipping, coaching
Medication, clinician visits, shipping
FSA/HSA accepted
Yes
Not listed
Terms & safety
Price shown
Before intake
Before intake
Cancel anytime
Yes
Yes
Minimum commitment
None
None on monthly plans; 3-month plans are billed every 3 months
Refunds
Full refund only if canceled within 72 hours before any services or if medically disqualified; monthly charges are non-refundable
'All sales are final' for prescription products; refund requests 'reviewed on a case-by-case basis'
FDA warning letters
None on record
None on record
Provider facts checked
October 2026
October 2026
Show where they differ by stateHide state lists
Only Vytora Health (DC)
- District of Columbia
Every dose and plan: Medsol RX · Vytora Health
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Which fits your priorities?
Only the points where these two differ, from the table above and each provider’s record.

Choose Medsol RX if…
- Lists compounded tirzepatide (pill or injection), oral compounded semaglutide and brand-name Wegovy / Ozempic, which Vytora Health doesn't price
- Accepts FSA/HSA cards
- Every plan includes a dedicated care coach, custom treatment plan, medical oversight and shipping
What to weigh up
- About $120 a year more than Vytora Health for compounded tirzepatide
- Not available in District of Columbia

Choose Vytora Health if…
- About $120 a year less than Medsol RX for compounded tirzepatide at standing prices
- Serves District of Columbia, where Medsol RX doesn't
- Both compounded and brand-name options on one platform
What to weigh up
- Brand-name Mounjaro and Zepbound at $1,399/mo are priced at retail; manufacturer self-pay programs are often cheaper
- Compounded tirzepatide at $249/mo month-to-month is mid-market
Explore the scoring factors
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
Medsol RX
7.4/10
Vytora Health
8.4/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Ready to start? Vetted GLP-1 providers
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From $79/mo (sale price)
Get started →Gala
Compounded semaglutide or tirzepatide at one all-doses price on a yearly plan, with free shipping
Read full review →From $129/mo (starting dose)
Get started →Found
Medication-included compounded GLP-1 from $169/mo on a 12-month prepaid plan, plus brand insurance help
Read full review →From $169/mo (12-month plan rate)
Get started →Medsol RX vs Vytora Health: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.