Amazon One Medical vs SkinnyRx
Our featured pick: SkinnyRx (affiliate partner). In our scoring, Amazon One Medical scores 8.5 and SkinnyRx 7.6 out of 10, and Amazon One Medical costs less for brand-name Wegovy / Ozempic (about $14,213 a year less; one bills every 4 weeks (13 charges a year), so this compares modeled yearly cost).
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Key differences
- Price
- Amazon One Medical $199/mo vs SkinnyRx $1,400/mo for brand-name Wegovy / Ozempic (standing prices, no prepay or separate membership listed · about $14,213 a year less with Amazon One Medical · one bills every 4 weeks (13 charges a year), so this compares modeled yearly cost)
- Coverage
- Amazon One Medical 50 states (SkinnyRx doesn't publish a state list)
- Included
- Amazon One Medical: clinician visits, shipping (not included: medication, labs); SkinnyRx: medication, clinician visits, shipping
- Safety
- FDA warning letters on record: Amazon One Medical none, SkinnyRx 1
Amazon One Medical
Best for brand-name GLP-1s with published per-dose cash prices and Amazon Pharmacy delivery
Brand-name Wegovy / Ozempic
$199
billed every 4 weeks
Our score 8.5/10
SkinnyRx
Affiliate partnerBest for compounded semaglutide or tirzepatide with the consult and free overnight shipping in one price
semaglutide
$149.25
Our score 7.6/10
We may earn a commission if you sign up through these links. Partner status can affect which provider we feature; it never changes a score or a price.
Costs & coverage
Published prices with their terms attached. Yearly figures are modeled from the standing price and billing cadence. A check mark marks the better side, on like-for-like rows only.
Amazon One Medical
SkinnyRx
Price
Brand Wegovy / Ozempic / month
Better on this row: $199/mo
billed every 4 weeks
$1,400/mo
Brand Wegovy / Ozempic / year (modeled)
Better on this row: $2,587
13 charges
$16,800
Brand Zepbound / Mounjaro / month
Better on this row: $299/mo
billed every 4 weeks
$1,400/mo
Brand Zepbound / Mounjaro / year (modeled)
Better on this row: $3,887
13 charges
$16,800
Semaglutide / month
Not listed
$149.25/mo
Tirzepatide / month
Not listed
$224.25/mo
Oral semaglutide / month
Not listed
$199/mo
Brand Wegovy pill / Rybelsus / month
$149/mo
Not listed
Brand Foundayo / month
$149/mo
Not listed
Coverage
State availability
50 states
List not published
Oral option listed
Yes
Yes
Brand-name access listed
Wegovy / Ozempic, Zepbound / Mounjaro, Wegovy pill / Rybelsus, Foundayo
Wegovy / Ozempic, Zepbound / Mounjaro
Included in the price
Clinician visits, shipping
Not included: medication, labs
Medication, clinician visits, shipping
Terms & safety
Price shown
Before intake
Plan quoted after intake; a price is published
Lab work
Required
Not disclosed
Refunds
Not disclosed
90-day money-back guarantee
FDA warning letters
Better on this row: None on record
1 warning letter
Provider facts checked
October 2026
August 2026
Every dose and plan: Amazon One Medical · SkinnyRx
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Which fits your priorities?
Only the points where these two differ, from the table above and each provider’s record.
Choose Amazon One Medical if…
- About $14,213 a year less than SkinnyRx for brand-name Wegovy / Ozempic at standing prices (one bills every 4 weeks (13 charges a year), so this compares modeled yearly cost)
- Lists brand-name Wegovy pill / Rybelsus and brand-name Foundayo, which SkinnyRx doesn't price
- Publishes its full state list (50 states)
What to weigh up
- Price doesn't include medication
- Online On-Demand Care is cash-only for medication; insurance needs scheduled visits near a One Medical office
Choose SkinnyRx if…
- Lists compounded semaglutide, compounded tirzepatide and oral compounded semaglutide, which Amazon One Medical doesn't price
- Price includes medication; Amazon One Medical's doesn't
- Licensed US clinicians on every prescription
What to weigh up
- 1 FDA warning letter on record
- About $14,213 a year more than Amazon One Medical for brand-name Wegovy / Ozempic (one bills every 4 weeks (13 charges a year), so this compares modeled yearly cost)
Explore the scoring factors
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
Amazon One Medical
8.5/10
SkinnyRx
7.6/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Ready to start? Vetted GLP-1 providers
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GobyMeds
No-membership, no-auto-renew compounded GLP-1 orders, from about $99/mo on a 3-month bundle
Read full review →From $169/mo
Get started →Ivim Health
Compounded GLP-1 with weekly provider check-ins and health coaches, under a required monthly membership
Read full review →From $65/mo + membership
Get started →From $247/mo
Get started →Amazon One Medical vs SkinnyRx: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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Or see the full category ranking.
Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.