PlexusDx vs Sesame Care
In our scoring, Sesame Care edges ahead overall (8.0 vs 7.0 out of 10).
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Key differences
- Price
- PlexusDx $129/mo for compounded semaglutide; Sesame Care $349/mo for brand-name Wegovy / Ozempic (different medications, so not compared on price)
- Coverage
- PlexusDx 50 states (Sesame Care doesn't publish a state list)
- Included
- PlexusDx: medication, clinician visits; Sesame Care: not stated
PlexusDx
Affiliate partnerBest for nationwide compounded GLP-1 with optional genetic-test personalization
semaglutide
$129
microdose plan
Our score 7.0/10
Sesame Care
Affiliate partnerBest for Brand-name GLP-1s at cash prices, no compounding
Brand-name Wegovy / Ozempic
$349
$199 first month
Our score 8.0/10
We may earn a commission if you sign up through these links. Partner status can affect which provider we feature; it never changes a score or a price.
Costs & coverage
Published prices with their terms attached. Yearly figures are modeled from the standing price and billing cadence. A check mark marks the better side, on like-for-like rows only.
PlexusDx
Sesame Care
Price
Semaglutide / month
$129/mo
microdose plan
Not listed
Tirzepatide / month
$249/mo
starting dose
Not listed
Brand Wegovy / Ozempic / month
Not listed
$349/mo
$199 first month
Brand Zepbound / Mounjaro / month
Not listed
$299/mo
Brand Wegovy pill / Rybelsus / month
Not listed
$149/mo
Brand Foundayo / month
Not listed
$149/mo
Coverage
State availability
50 states
List not published
Oral option listed
Not listed
Yes
Brand-name access listed
Not listed
Wegovy / Ozempic, Zepbound / Mounjaro, Wegovy pill / Rybelsus, Foundayo
Included in the price
Medication, clinician visits
Not disclosed
Terms & safety
Price shown
Before intake
Before intake
Video visit
Not disclosed
Required
Cancel anytime
Not disclosed
Yes
Minimum commitment
Not disclosed
None
Early-cancellation fee
Not disclosed
None
FDA warning letters
None on record
None on record
Provider facts checked
August 2026
August 2026
Every dose and plan: PlexusDx · Sesame Care
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Which fits your priorities?
Only the points where these two differ, from the table above and each provider’s record.
Choose PlexusDx if…
- Lists compounded semaglutide and compounded tirzepatide, which Sesame Care doesn't price
- Publishes its full state list (50 states)
- Optional Precision Peptide genetic panel adds a personalization angle
What to weigh up
- Compounded medications only; no FDA-approved brand options
- Specific compounding pharmacies not named
Choose Sesame Care if…
- Lists brand-name Wegovy / Ozempic, brand-name Zepbound / Mounjaro and brand-name Wegovy pill / Rybelsus, which PlexusDx doesn't price
- Marketplace transparency — pick a named provider with a displayed price before booking, unlike most opaque telehealth intake
- BBB-accredited and LegitScript-certified
What to weigh up
- No published state list; confirm yours at signup
- Marketplace model means clinician credentials and quality vary provider to provider
Explore the scoring factors
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
PlexusDx
7.0/10
Sesame Care
8.0/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
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bmiMD
One flat compounded GLP-1 price at every dose: semaglutide $159/mo month to month, $119/mo on a 12-month plan
Read full review →From $159/mo
Get started →altRX
Low-cost compounded GLP-1s with brand-name Zepbound, Wegovy and Ozempic as options
Read full review →From $89/mo
Get started →RxSpan MD
Physician-led, pharmacy-transparent compounded GLP-1 with brand-name options
Read full review →From $249/mo
Get started →PlexusDx vs Sesame Care: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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Or see the full category ranking, or alternatives to PlexusDx and Sesame Care.
Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.