PlexusDx vs ShedRx
In our scoring, ShedRx edges ahead overall (8.0 vs 7.0 out of 10).
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Key differences
- Price
- PlexusDx $129/mo no prepay listed; ShedRx $199/mo no prepay listed (compounded semaglutide · not like-for-like, so neither is marked cheaper)
- Coverage
- PlexusDx 50 states (ShedRx doesn't publish a state list)
- Included
- PlexusDx: medication, clinician visits; ShedRx: medication, clinician visits, coaching
PlexusDx
Affiliate partnerBest for nationwide compounded GLP-1 with optional genetic-test personalization
semaglutide
$129
microdose plan
Our score 7.0/10
ShedRx
Affiliate partnerBest for compounded GLP-1 as an injection, drops or lozenges, with lower rates on 6- and 12-month plans
semaglutide
$199
$159 first month
Our score 8.0/10
We may earn a commission if you sign up through these links. Partner status can affect which provider we feature; it never changes a score or a price.
Costs & coverage
Published prices with their terms attached. Yearly figures are modeled from the standing price and billing cadence. A check mark marks the better side, on like-for-like rows only.
PlexusDx
ShedRx
Price
Semaglutide / month
$129/mo
microdose plan
$199/mo
$159 first month
Semaglutide / year (modeled)
$1,548
$2,388
Tirzepatide / month
$249/mo
starting dose
$299/mo
$239 first month
Tirzepatide / year (modeled)
$2,988
$3,588
Semaglutide (pill or injection) / month
Not listed
$149/mo
+ separate membership
Oral semaglutide / month
Not listed
$199/mo
“starting at” price
Brand Foundayo / month
Not listed
$149/mo
+ separate membership
Separate membership required
Not stated
Yes — not in the listed price
Coverage
State availability
50 states
List not published
Oral option listed
Not listed
Yes
Brand-name access listed
Not listed
Foundayo
Included in the price
Medication, clinician visits
Medication, clinician visits, coaching
Terms & safety
Price shown
Before intake
Plan quoted after intake; a price is published
Video visit
Not disclosed
Not required
Minimum commitment
Not disclosed
None
Refunds
Not disclosed
120-day money-back guarantee
FDA warning letters
None on record
None on record
Provider facts checked
August 2026
August 2026
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Which fits your priorities?
Only the points where these two differ, from the table above and each provider’s record.
Choose PlexusDx if…
- Publishes its full state list (50 states)
- Optional Precision Peptide genetic panel adds a personalization angle
- Independent clinician review via state-licensed telehealth platform
What to weigh up
- Compounded medications only; no FDA-approved brand options
- Specific compounding pharmacies not named
Choose ShedRx if…
- Lists compounded semaglutide (pill or injection), oral compounded semaglutide and brand-name Foundayo, which PlexusDx doesn't price
- Multiple administration formats
What to weigh up
- No published state list; confirm yours at signup
Explore the scoring factors
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
PlexusDx
7.0/10
ShedRx
8.0/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Ready to start? Vetted GLP-1 providers
Vetted telehealth providers that prescribe GLP-1 online.
No insurance needed · vetted by our editors
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RxSpan MD
Physician-led, pharmacy-transparent compounded GLP-1 with brand-name options
Read full review →From $249/mo
Get started →Luvo Health
Compounded and brand GLP-1s, oral tablets and microdosing on one public price list
Read full review →From $209/4 wks (billed per 4 weeks)
Get started →From $99/mo (“starting at” price)
Get started →PlexusDx vs ShedRx: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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Or see the full category ranking, or alternatives to PlexusDx and ShedRx.
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