PlexusDx vs Ro
In our scoring, Ro edges ahead overall (7.7 vs 7.0 out of 10).
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Key differences
- Price
- PlexusDx $129/mo for compounded semaglutide; Ro $349/mo for brand-name Wegovy / Ozempic (different medications, so not compared on price)
- Coverage
- PlexusDx 50 states (Ro doesn't publish a state list)
- Included
- PlexusDx: medication, clinician visits; Ro: clinician visits, labs, coaching (not included: medication)
PlexusDx
Affiliate partnerBest for nationwide compounded GLP-1 with optional genetic-test personalization
semaglutide
$129
microdose plan
Our score 7.0/10
Ro
Affiliate partnerBest for FDA-approved brand GLP-1s, including the Wegovy pill and Foundayo, with insurance help
Brand-name Wegovy / Ozempic
$349
+ separate membership · $199 first month
Our score 7.7/10
We may earn a commission if you sign up through these links. Partner status can affect which provider we feature; it never changes a score or a price.
Costs & coverage
Published prices with their terms attached. Yearly figures are modeled from the standing price and billing cadence. A check mark marks the better side, on like-for-like rows only.
PlexusDx
Ro
Price
Semaglutide / month
$129/mo
microdose plan
Not listed
Tirzepatide / month
$249/mo
starting dose
Not listed
Brand Wegovy / Ozempic / month
Not listed
$349/mo
+ separate membership · $199 first month
Brand Zepbound / Mounjaro / month
Not listed
$299/mo
+ separate membership
Brand Wegovy pill / Rybelsus / month
Not listed
$149/mo
+ separate membership · other plan terms available
Brand Foundayo / month
Not listed
$149/mo
+ separate membership
Separate membership required
Not stated
Yes — not in the listed price
Coverage
State availability
50 states
List not published
Oral option listed
Not listed
Yes
Brand-name access listed
Not listed
Wegovy / Ozempic, Zepbound / Mounjaro, Wegovy pill / Rybelsus, Foundayo
Included in the price
Medication, clinician visits
Clinician visits, labs, coaching
Not included: medication
Terms & safety
Price shown
Before intake
Before intake
Cancel anytime
Not disclosed
Yes
Minimum commitment
Not disclosed
None required; optional 3-, 6- and 12-month prepaid membership plans ('You'll pay upfront for your entire multi-month membership or medication plan').
Refunds
Not disclosed
'Your previously incurred monthly fees are nonrefundable.' Prescription products: 'all sales are final.' The $39 first month 'will be refunded if you're not eligible for GLP-1s.'
FDA warning letters
None on record
None on record
Provider facts checked
August 2026
October 2026
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Which fits your priorities?
Only the points where these two differ, from the table above and each provider’s record.
Choose PlexusDx if…
- Lists compounded semaglutide and compounded tirzepatide, which Ro doesn't price
- Publishes its full state list (50 states)
- Price includes medication; Ro's doesn't
What to weigh up
- Compounded medications only; no FDA-approved brand options
- Specific compounding pharmacies not named
Choose Ro if…
- Lists brand-name Wegovy / Ozempic, brand-name Zepbound / Mounjaro and brand-name Wegovy pill / Rybelsus, which PlexusDx doesn't price
- Broad FDA-approved menu: Wegovy pill and pen, Zepbound, Foundayo and Ozempic
- Cash prices match LillyDirect, NovoCare and TrumpRx, with every dose price published
What to weigh up
- Listed brand-name Wegovy / Ozempic price excludes a required membership
- No published state list; confirm yours at signup
Explore the scoring factors
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
PlexusDx
7.0/10
Ro
7.7/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
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Ro
FDA-approved brand GLP-1s, including the Wegovy pill and Foundayo, with insurance help
Read full review →From $149/mo (+ required membership)
Get started →ShedRx
Compounded GLP-1 as an injection, drops or lozenges, with lower rates on 6- and 12-month plans
Read full review →From $299/mo (after intro offer)
Get started →bmiMD
One flat compounded GLP-1 price at every dose: semaglutide $159/mo month to month, $119/mo on a 12-month plan
Read full review →From $159/mo
Get started →PlexusDx vs Ro: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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Or see the full category ranking, or alternatives to PlexusDx and Ro.
Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.