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One80Rx vs CoreAge Rx

An in-depth comparison of two leading GLP-1 Providers

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By Eli Marsden · Founding Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed
One80Rx logo

One80Rx

6.8
★★★☆☆3.4/5

Best for: low listed GLP-1 prices with flat dosing, including microdose and oral options

Visit One80Rx →
VS
CoreAge Rx logo

CoreAge Rx

8.3
★★★★☆4.2/5

Best for: best overall value

Visit CoreAge Rx →

One80Rx and CoreAge Rx are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, CoreAge Rx starts lower at $99/mo versus $129/mo, and CoreAge Rx edges ahead overall (8.3 vs 6.8 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.

Pricing

One80Rx

Listed from-price; plan length not shown before checkout (Terms: billed every 30 days)Compounded
$129/mo
semaglutide

Card reads "from $129/mo"; the site says plans are confirmed after provider review.

Listed from-price; plan length not shown before checkout (Terms: billed every 30 days)Compounded
$229/mo
tirzepatide

Card reads "from $229/mo"; the site says plans are confirmed after provider review.

CoreAge Rx

Injectable, monthly auto-refill (flat across all dosages)Compounded
$99/mo
semaglutide

same price at every dose

Injectable, monthly auto-refill (flat across all dosages)Compounded
$149/mo
tirzepatide

same price at every dose

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What’s included

One80Rx

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

CoreAge Rx

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

Score breakdown

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

One80Rx

6.8/10

Overall

CoreAge Rx

8.3/10

Value25%

7.5A
vs
B
8.5

Effectiveness25%

7.5A
vs
B
8.5

User Experience15%

6.5A
vs
B
8.5

Trust & Safety15%

4.5A
vs
B
7.8

Accessibility10%

6.5A
vs
B
8.0

Support10%

7.0A
vs
B
8.4

Features & Coverage

FeatureOne80RxCoreAge Rx
Starting Price$129/mo✓$99/mo
Features✓8 features6 features
States AvailableNot disclosed50
Compounded✓ Yes✓ Yes
Brand Name——
FSA/HSA Accepted——
FDA WarningsNoneNone

About One80Rx

One80Rx is a Tampa-based telehealth platform selling compounded semaglutide and tirzepatide injections, plus a GLP-1 microdose program, an oral GLP-1 and a long list of peptides. Listed prices start at $129/mo for semaglutide and $229/mo for tirzepatide, and the site promises flat pricing with no dose-change surcharge. The catch is that every price is a "from" figure confirmed only after provider review, and the brand launched in mid-2026.

Read our full One80Rx review →

About CoreAge Rx

CoreAge Rx offers LegitScript-certified compounded semaglutide and tirzepatide with free 2-day shipping to all 50 states. Backed by licensed physicians and 24/7 support, it delivers the most competitive pricing in the compounded GLP-1 space.

Read our full CoreAge Rx review →

Pros & Cons

One80Rx

What we like

  • Low listed entry prices: semaglutide from $129/mo and tirzepatide from $229/mo
  • Flat-rate pricing is promised with no consultation fee and no surcharge when your dose goes up
  • $0 if a provider does not approve you, and the Terms refund you if no prescription is issued
  • Four GLP-1 formats, including a lower-dose microdose program and a daily oral option
  • Free 2–3 day shipping in temperature-controlled, unmarked packaging
  • Support phone line and email published, with weekday hours of 9 AM to 5 PM
  • Cancel from your patient portal by turning off auto-refill at least 48 hours before the next charge

Watch-outs

  • Every price is a "from" figure confirmed only after provider review; the treatment pages show no price at all
  • No price appears in the intake before it asks for your name, email, phone, birth date and shipping address
  • Neither the compounding pharmacy nor the prescribing medical group is named anywhere on the site
  • Shows a Trustpilot "4.8 / 5" rating, but no Trustpilot profile for the brand could be found
  • Brand launched in mid-2026, yet the homepage claims "10k+" members beside a "1,743+ patients supported" counter
  • Terms make you waive the right to fill your prescription at a pharmacy of your choice
  • No refunds once medication is dispensed, and order cancellation is limited to 24 hours after purchase
  • Compounded semaglutide and tirzepatide are not FDA-approved, as the site itself states

CoreAge Rx

What we like

  • LegitScript certified — rigorous pharmacy standards
  • Free 2-day shipping nationwide
  • Both semaglutide and tirzepatide available
  • Lowest per-month pricing in the compounded segment
  • 24/7 support team
  • All 50 states covered

Watch-outs

  • Compounded only — no brand-name Ozempic or Wegovy
  • Newer brand with fewer independent reviews than legacy players

Our Verdict

Winner: CoreAge Rx

CoreAge Rx edges out One80Rx with a higher overall score of 8.3/10 and is particularly strong for best overall value. One80Rx remains a solid alternative, especially if you're looking for low listed GLP-1 prices with flat dosing, including microdose and oral options.

Choose One80Rx if…

You want low listed GLP-1 prices with flat dosing, including microdose and oral options and a starting price around $129/mo.

Choose CoreAge Rx if…

You want best overall value and a starting price around $99/mo.

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7.3

Sunlight

Compounded GLP-1 with unlimited telehealth visits and free shipping

7.4

MadeMed

Compounded GLP-1 in both injection and oral forms

8.3

Found

Mainstream telehealth GLP-1 access

One80Rx vs CoreAge Rx: FAQ

CoreAge Rx is cheaper. Its lowest ongoing monthly cash price is $99/mo, compared with $129/mo for One80Rx. We compare standing (not first-month promo) prices so the figures reflect what you'd actually pay month to month.
CoreAge Rx scores higher overall at 8.3/10 versus 6.8/10, and is particularly strong for best overall value. That said, One80Rx is a better fit if you want low listed GLP-1 prices with flat dosing, including microdose and oral options.
CoreAge Rx lists availability in 50 states, while One80Rx's state list is not publicly listed.
CoreAge Rx is an affiliate partner (we may earn a commission on sign-ups through our links); One80Rx is not. Either way, we rank providers editorially with the same scoring framework and disclose every partnership — being a partner does not buy a higher score.
For Semaglutide, CoreAge Rx is cheaper at $99/mo versus $129/mo at One80Rx.

Key terms, explained

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Continue exploring One80Rx and CoreAge Rx head-to-heads in the same category.

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