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NP2GO vs NewSelf

An in-depth comparison of two leading GLP-1 Providers

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By Eli Marsden · Founding Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed
NP2GO logo

NP2GO

7.8
★★★3.9/5

Best for: transparent per-dose pricing with pay-as-you-go or membership options

Visit NP2GO
VS
NewSelf logo

NewSelf

8.3
★★★★4.2/5

Best for: lowest-cost compounded GLP-1 with pharmacy quality transparency

Visit NewSelf

NP2GO and NewSelf are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, NewSelf starts lower at $100/mo versus $150/mo, and NewSelf edges ahead overall (8.3 vs 7.8 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.

Pricing

NP2GO

0.25mg (Pay As You Go)Compounded
$150/mo
semaglutide
0.50mg (Pay As You Go)Compounded
$175/mo
semaglutide
1mg (Pay As You Go)Compounded
$235/mo
semaglutide
1.7mg (Pay As You Go)Compounded
$250/mo
semaglutide
2.5mg (Pay As You Go)Compounded
$350/mo
semaglutide
0.25-1mg (Month-to-Month Membership)Compounded
$199/mo
semaglutide
1.7-2.5mg (Month-to-Month Membership)Compounded
$299/mo
semaglutide
2.5mg (Pay As You Go)Compounded
$250/mo
tirzepatide
5mg (Pay As You Go)Compounded
$300/mo
tirzepatide
7.5mg (Pay As You Go)Compounded
$375/mo
tirzepatide
10mg (Pay As You Go)Compounded
$475/mo
tirzepatide
12.5mg (Pay As You Go)Compounded
$550/mo
tirzepatide
15mg (Pay As You Go)Compounded
$600/mo
tirzepatide
2.5-7.5mg (Month-to-Month Membership)Compounded
$299/mo
tirzepatide
10-15mg (Month-to-Month Membership)Compounded
$399/mo
tirzepatide

NewSelf

Semaglutide+ (best price)Compounded
$100/mo
semaglutide

All dosages same price

Semaglutide+ (regular)Compounded
$135/mo
semaglutide
Tirzepatide+ (best price)Compounded
$144/mo
tirzepatide

All dosages same price

Tirzepatide+ (regular)Compounded
$225/mo
tirzepatide

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What’s included

NP2GO

Inclusions not disclosed.

NewSelf

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

Score breakdown

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

NP2GO

7.8/10

Overall

NewSelf

8.3/10

Value25%

7.5A
vs
B
9.0

Effectiveness25%

8.0A
vs
B
8.0

User Experience15%

7.5A
vs
B
8.0

Trust & Safety15%

7.8A
vs
B
8.3

Accessibility10%

7.5A
vs
B
8.5

Support10%

8.4A
vs
B
7.9

Features & Coverage

FeatureNP2GONewSelf
Starting Price$150/mo$100/mo
Features8 features6 features
States Available4049
Compounded✓ Yes✓ Yes
Brand Name
FSA/HSA Accepted
FDA WarningsNoneNone

About NP2GO

NP2GO is a nurse-practitioner-led hybrid telehealth and clinic operation based in Edmond, Oklahoma, founded in 2019 and affiliated with the Obesity Medicine Association. It publishes its full compounded semaglutide and tirzepatide pricing matrix openly, with two paths: Pay As You Go (per-dose, $99 visit fee every 3 months) or a flat Month-to-Month Membership. Entry semaglutide starts at $150/mo; virtual weight-loss visits reach 39 states plus DC.

Read our full NP2GO review →

About NewSelf

NewSelf offers compounded semaglutide+ (with B12/Glycine, from $99.97/mo) and compounded tirzepatide+ (with B6/Glycine, from $144.49/mo). LegitScript certified. Available in 48 states + Puerto Rico. Uses 503A licensed pharmacies with third-party testing.

Read our full NewSelf review →

Pros & Cons

NP2GO

What we like

  • Full per-dose pricing matrix published — you can see the cost at every dose tier before committing
  • Two pricing models (Pay As You Go and Month-to-Month Membership) let you match your usage pattern
  • Compounded semaglutide starts at $150/mo (0.25 mg, Pay As You Go) — competitive with the market low end
  • Covers 39 states plus DC
  • Files prior authorizations on your behalf — uncommon for compounded telehealth
  • Nurse-practitioner-led care with Obesity Medicine Association membership

Watch-outs

  • High-dose tirzepatide runs $475–$600/mo on Pay As You Go (membership at $399/mo is better for high doses)
  • Not LegitScript-certified
  • Compounding pharmacy partner not named publicly
  • Not available in 11 states (AL, GA, IN, LA, MO, MS, NC, OH, SC, TN, WI)
  • Peptide, hormone, and aesthetic services are Oklahoma-only
  • $99 visit fee every 3 months (PAYG) is on top of the per-dose cost

NewSelf

What we like

  • Semaglutide+ from $99.97/mo — among the lowest prices in the dataset
  • All dosages at the same price — no price escalation as dose increases
  • LegitScript certified with 503A licensed pharmacies
  • Third-party potency, sterility, and endotoxicity testing
  • 48 states + Puerto Rico coverage
  • B12/B6 + Glycine enhanced formulations
  • No membership fees

Watch-outs

  • Not available in Mississippi and Louisiana
  • Compounded only — no brand-name options
  • Site also promotes AI health optimization and longevity (broader platform)

Our Verdict

Winner: NewSelf

NewSelf edges out NP2GO with a higher overall score of 8.3/10 and is particularly strong for lowest-cost compounded GLP-1 with pharmacy quality transparency. NP2GO remains a solid alternative, especially if you're looking for transparent per-dose pricing with pay-as-you-go or membership options.

Choose NP2GO if…

You want transparent per-dose pricing with pay-as-you-go or membership options and a starting price around $150/mo.

Choose NewSelf if…

You want lowest-cost compounded GLP-1 with pharmacy quality transparency and a starting price around $100/mo.

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