NP2GO vs Amazon One Medical
An in-depth comparison of two leading GLP-1 Providers
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NP2GO
Best for transparent per-dose pricing with pay-as-you-go or membership optionsStarting at $150/mo
Amazon One Medical
Best for the most authoritative branded GLP-1 channel with same-day delivery and integrated manufacturer savingsStarting at $25/mo
Side-by-Side Comparison
| Feature | NP2GO | Amazon One Medical |
|---|---|---|
| Overall Score | 7.9/10 | ✓8.7/10 |
| Starting Price | $150/mo | ✓$25/mo |
| Editorial Rating | 4 ★ /5 | ✓4.4 ★ /5 |
| Features | ✓8 features | 6 features |
| States Available | 40 | ✓50 |
| Compounded | ✓ Yes | — |
| Brand Name | — | ✓ Yes |
| FSA/HSA Accepted | — | — |
| FDA Warnings | None | None |
Pros & Cons
NP2GO
Pros
- ✓Full per-dose pricing matrix published — you can see the cost at every dose tier before committing
- ✓Two pricing models (Pay As You Go and Month-to-Month Membership) let you match your usage pattern
- ✓Compounded semaglutide starts at $150/mo (0.25 mg, Pay As You Go) — competitive with the market low end
- ✓Covers 39 states plus DC
- ✓Files prior authorizations on your behalf — uncommon for compounded telehealth
- ✓Nurse-practitioner-led care with Obesity Medicine Association membership
Cons
- ✗High-dose tirzepatide runs $475–$600/mo on Pay As You Go (membership at $399/mo is better for high doses)
- ✗Not LegitScript-certified
- ✗Compounding pharmacy partner not named publicly
- ✗Not available in 11 states (AL, GA, IN, LA, MO, MS, NC, OH, SC, TN, WI)
- ✗Peptide, hormone, and aesthetic services are Oklahoma-only
- ✗$99 visit fee every 3 months (PAYG) is on top of the per-dose cost
Amazon One Medical
Pros
- ✓As low as $1/day ($25/month) for brand-name Foundayo with insurance and the auto-applied Lilly coupon
- ✓Same-day delivery in nearly 3,000 US cities at launch, expanding to 4,500 by end of 2026
- ✓In-office pharmacist kiosks at select One Medical clinics let you walk out with Foundayo in hand
- ✓Cash-pay $5/day ($149/month) is competitive for the same FDA-approved brand-name product
- ✓Real-time availability, transparent pricing, and automatic manufacturer coupon at checkout
- ✓Delivering GLP-1 medications since 2021 — track record on cold-chain logistics
Cons
- ✗Headline $25/month needs both insurance and the Lilly Savings Card — uninsured pay $149/month
- ✗Same-day delivery is geographically gated; outside major cities it drops to next-day or slower
- ✗Pricing is set by manufacturer savings programs and can change at any time
- ✗No compounded options — brand-name only (Foundayo, Wegovy, Zepbound)
- ✗Wegovy/Zepbound pricing isn't shown upfront — depends on insurance at the prescribing visit
- ✗Copays and deductibles still apply to the clinical visit
Our Verdict
Amazon One Medical edges out NP2GO with a higher overall score of 8.7/10 and is particularly strong for the most authoritative branded GLP-1 channel with same-day delivery and integrated manufacturer savings. NP2GO remains a solid alternative, especially if you're looking for transparent per-dose pricing with pay-as-you-go or membership options.
Glossary references
Key terms in this article, linked to their canonical definitions.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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Or see the full category ranking.
Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.