NewSelf vs Vital Harmony Rx
An in-depth comparison of two leading GLP-1 Providers
WeightLossRankings.org is reader-supported. When you buy through links on our site, we may earn an affiliate commission. Learn more
NewSelf
Best for: lowest-cost compounded GLP-1 with pharmacy quality transparency
Visit NewSelf →
Vital Harmony Rx
Best for: LegitScript-verified compounded GLP-1 with semaglutide and tirzepatide options
Visit Vital Harmony Rx →NewSelf and Vital Harmony Rx are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, NewSelf starts at $100/mo, and NewSelf edges ahead overall (8.3 vs 6.0 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.
Pricing
NewSelf
All dosages same price
All dosages same price
Vital Harmony Rx
Pricing not publicly listed.
Get alerted when GLP-1 prices drop
Join the GLP-1 price-watch list — we re-verify 390+ providers' prices on their own sites and email you when tracked prices move.
What’s included
NewSelf
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Included
Lab work
Not disclosed
Coaching
Not disclosed
Vital Harmony Rx
Inclusions not disclosed.
Score breakdown
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
NewSelf
8.3/10
Vital Harmony Rx
6.0/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Features & Coverage
| Feature | NewSelf | Vital Harmony Rx |
|---|---|---|
| Starting Price | $100/mo | — |
| Features | ✓6 features | 4 features |
| States Available | 49 | Not disclosed |
| Compounded | ✓ Yes | — |
| Brand Name | — | — |
| FSA/HSA Accepted | — | — |
| FDA Warnings | None | None |
About NewSelf
NewSelf offers compounded semaglutide+ (with B12/Glycine, from $99.97/mo) and compounded tirzepatide+ (with B6/Glycine, from $144.49/mo). LegitScript certified. Available in 48 states + Puerto Rico. Uses 503A licensed pharmacies with third-party testing.
Read our full NewSelf review →About Vital Harmony Rx
Vital Harmony Rx is a telehealth platform offering compounded injectable GLP-1 therapy — semaglutide (GLP-1 + B12) and tirzepatide (GLP-1/GIP + B12) — plus a wellness-peptide menu of NAD+, sermorelin, and glutathione. Care runs through an independent physician network (Beluga Health), and the site carries a verified LegitScript seal. Services are offered nationwide; note that no pricing is published on the site, so cost can't be compared in advance.
Read our full Vital Harmony Rx review →Pros & Cons
NewSelf
What we like
- Semaglutide+ from $99.97/mo — among the lowest prices in the dataset
- All dosages at the same price — no price escalation as dose increases
- LegitScript certified with 503A licensed pharmacies
- Third-party potency, sterility, and endotoxicity testing
- 48 states + Puerto Rico coverage
- B12/B6 + Glycine enhanced formulations
- No membership fees
Watch-outs
- Not available in Mississippi and Louisiana
- Compounded only — no brand-name options
- Site also promotes AI health optimization and longevity (broader platform)
Vital Harmony Rx
What we like
- Verified LegitScript certification (ID 49230211) — a trust signal many compounded-GLP-1 DTC brands lack
- Explicit compounded-medication + 'not a pharmacy/manufacturer' disclosure on-site
- Both a semaglutide (GLP-1+B12) and a tirzepatide (GLP-1/GIP+B12) option
- Operates on a named physician network (Beluga Health)
Watch-outs
- NO pricing published anywhere on the site — a major gap for a cost-comparison directory; buyers cannot evaluate value without contacting the company
- No specific state list (only 'entire country' claimed)
- No named compounding pharmacy partner
- No named medical director / PIC, no legal entity or governing law disclosed
- Molecule strengths/dose tiers not published
Our Verdict
NewSelf edges out Vital Harmony Rx with a higher overall score of 8.3/10 and is particularly strong for lowest-cost compounded GLP-1 with pharmacy quality transparency. Vital Harmony Rx remains a solid alternative, especially if you're looking for LegitScript-verified compounded GLP-1 with semaglutide and tirzepatide options.
Choose NewSelf if…
You want lowest-cost compounded GLP-1 with pharmacy quality transparency and a starting price around $100/mo.
Choose Vital Harmony Rx if…
You want LegitScript-verified compounded GLP-1 with semaglutide and tirzepatide options.
Ready to start? Vetted GLP-1 providers
Vetted telehealth providers that prescribe GLP-1 online.
No insurance needed · vetted by our editors
WeightLossRankings.org is reader-supported. When you buy through links on our site, we may earn an affiliate commission. Learn more
Liv Body
Compounded GLP-1 paired with a muscle-preservation supplement stack
From $179/mo
Get started →DudeMeds
Men seeking no-fee GLP-1 access with oral and injectable options
From $175/mo
Get started →Yucca Health
Mainstream telehealth GLP-1 access
From $146/mo
Get started →NewSelf vs Vital Harmony Rx: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
Related comparisons
Continue exploring NewSelf and Vital Harmony Rx head-to-heads in the same category.
- NewSelf vs Amazon One Medical
- NewSelf vs Vytora Health
- NewSelf vs CoreAge Rx
- Vital Harmony Rx vs EverSlim
- Vital Harmony Rx vs Found
- Vital Harmony Rx vs Elara Health and Wellness
Or see the full category ranking.
Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.