NewSelf vs Tru2u
An in-depth comparison of two leading GLP-1 Providers
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NewSelf
Best for: lowest-cost compounded GLP-1 with pharmacy quality transparency
Visit NewSelf →Tru2u
Best for: shoppers wanting compounded oral or injectable glp-1 options in one store
Visit Tru2u →NewSelf and Tru2u are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, NewSelf starts lower at $100/mo versus $225/mo, and NewSelf edges ahead overall (8.3 vs 6.5 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.
Pricing
NewSelf
All dosages same price
All dosages same price
Tru2u
Injectable, monthly subscription
Injectable, monthly subscription
Compounded oral semaglutide tablets
Compounded oral tirzepatide tablets
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What’s included
NewSelf
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Included
Lab work
Not disclosed
Coaching
Not disclosed
Tru2u
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Included
Lab work
Not disclosed
Coaching
Not disclosed
Score breakdown
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
NewSelf
8.3/10
Tru2u
6.5/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Features & Coverage
| Feature | NewSelf | Tru2u |
|---|---|---|
| Starting Price | ✓$100/mo | $225/mo |
| Features | ✓6 features | 5 features |
| States Available | 49 | Not disclosed |
| Compounded | ✓ Yes | ✓ Yes |
| Brand Name | — | — |
| FSA/HSA Accepted | — | — |
| FDA Warnings | None | None |
About NewSelf
NewSelf offers compounded semaglutide+ (with B12/Glycine, from $99.97/mo) and compounded tirzepatide+ (with B6/Glycine, from $144.49/mo). LegitScript certified. Available in 48 states + Puerto Rico. Uses 503A licensed pharmacies with third-party testing.
Read our full NewSelf review →About Tru2u
Tru2u is a US direct-to-consumer telehealth and wellness store offering provider-guided compounded GLP-1 weight-loss therapy alongside hair, skincare, and supplement lines. Weight-loss options include compounded injectable semaglutide and tirzepatide, a combined GLP Squared injection, and compounded oral semaglutide and tirzepatide tablets. Medication is prescribed only after a licensed-clinician consult, and orders route to an independent third-party pharmacy. Pricing is published upfront on a monthly subscription with free shipping. US residents only.
Read our full Tru2u review →Pros & Cons
NewSelf
What we like
- Semaglutide+ from $99.97/mo — among the lowest prices in the dataset
- All dosages at the same price — no price escalation as dose increases
- LegitScript certified with 503A licensed pharmacies
- Third-party potency, sterility, and endotoxicity testing
- 48 states + Puerto Rico coverage
- B12/B6 + Glycine enhanced formulations
- No membership fees
Watch-outs
- Not available in Mississippi and Louisiana
- Compounded only — no brand-name options
- Site also promotes AI health optimization and longevity (broader platform)
Tru2u
What we like
- Offers compounded semaglutide and tirzepatide plus a combined GLP Squared injection
- Both injectable and oral GLP-1 tablet options available
- Transparent upfront monthly pricing with free shipping
Watch-outs
- No compounding pharmacy publicly named and no LegitScript seal shown
- Tirzepatide at 345 dollars per month is higher than many compounded competitors
- States served are not published; site states US-only availability
Our Verdict
NewSelf edges out Tru2u with a higher overall score of 8.3/10 and is particularly strong for lowest-cost compounded GLP-1 with pharmacy quality transparency. Tru2u remains a solid alternative, especially if you're looking for shoppers wanting compounded oral or injectable glp-1 options in one store.
Choose NewSelf if…
You want lowest-cost compounded GLP-1 with pharmacy quality transparency and a starting price around $100/mo.
Choose Tru2u if…
You want shoppers wanting compounded oral or injectable glp-1 options in one store and a starting price around $225/mo.
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Try Ageless
Lowest-tier compounded GLP-1 in injection, troche and sublingual forms
From $119/mo
Get started →Sunlight
Compounded GLP-1 with unlimited telehealth visits and free shipping
From $159/mo
Get started →MadeMed
Compounded GLP-1 in both injection and oral forms
From $219/mo
Get started →NewSelf vs Tru2u: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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Or see the full category ranking.
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