Metabolic Rx vs NewSelf
An in-depth comparison of two leading GLP-1 Providers
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Metabolic Rx
Best for: people who want a flat price at every dose and can prepay for compounded semaglutide or tirzepatide
Visit Metabolic Rx →
NewSelf
Best for: lowest-cost compounded GLP-1 with pharmacy quality transparency
Visit NewSelf →Metabolic Rx and NewSelf are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, NewSelf starts lower at $100/mo versus $229/mo, and NewSelf edges ahead overall (8.3 vs 6.3 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.
Pricing
Metabolic Rx
$159 first month, then $259. A 3-month plan is $449 and a 6-month plan $849, each charged upfront
$149 first month, then $329. A 3-month plan is $597 and a 6-month plan $1,099, each charged upfront
$149 first month, then $229. Prepaid plans are shown at $166 a month for 3 months and $149 a month for 6 months
NewSelf
All dosages same price
All dosages same price
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What’s included
Metabolic Rx
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Included
Lab work
Not disclosed
Coaching
Included
NewSelf
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Included
Lab work
Not disclosed
Coaching
Not disclosed
Score breakdown
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
Metabolic Rx
6.3/10
NewSelf
8.3/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Features & Coverage
| Feature | Metabolic Rx | NewSelf |
|---|---|---|
| Starting Price | $229/mo | ✓$100/mo |
| Features | ✓7 features | 6 features |
| States Available | Not disclosed | 49 |
| Compounded | ✓ Yes | ✓ Yes |
| Brand Name | — | — |
| FSA/HSA Accepted | — | — |
| FDA Warnings | ✓None | 1 warning |
About Metabolic Rx
Metabolic Rx is a telehealth platform launched in 2026 that sells compounded semaglutide and tirzepatide injections and a daily oral semaglutide, with one flat price at every dose. Monthly plans renew at $259 for semaglutide and $329 for tirzepatide after a discounted first month of $159 or $149. The company does not name its medical group, pharmacies or the business behind it.
Read our full Metabolic Rx review →About NewSelf
NewSelf offers compounded semaglutide+ (with B12/Glycine, from $99.97/mo) and compounded tirzepatide+ (with B6/Glycine, from $144.49/mo). LegitScript certified. Available in 48 states + Puerto Rico. Uses 503A licensed pharmacies with third-party testing.
Read our full NewSelf review →Pros & Cons
Metabolic Rx
What we like
- One flat price at every dose, with medication, physician review, coaching and shipping included
- Discounted first month: $159 for semaglutide and $149 for tirzepatide
- Prepaying lowers semaglutide to about $142 to $150 a month and tirzepatide to $183 to $199 a month
- Offers a daily oral semaglutide option as well as weekly injections
- Refund if the prescribing clinician declines treatment or the order has not shipped
- Publishes a support phone number with weekday hours
Watch-outs
- The site does not name the company behind it, its medical group or the pharmacies that fill prescriptions
- Its privacy policy lists a placeholder mailing address rather than a real one
- Monthly plans renew at $259 for semaglutide and $329 for tirzepatide after the discounted first month
- The intake says you are approved before any clinician reviews it, then runs a 15-minute countdown at checkout
- You pay at checkout before a physician reviews your answers, and you must agree to calls and texts to continue
- The 3- and 6-month plans are charged upfront, though checkout says you pay one month at a time
- Its Trustpilot and Google rating badges could not be traced; there is no Trustpilot profile or LegitScript seal
- The cancellation notice period is unclear: 48 hours in the terms but 30 days in the FAQ
NewSelf
What we like
- Semaglutide+ from $99.97/mo — among the lowest prices in the dataset
- All dosages at the same price — no price escalation as dose increases
- LegitScript certified with 503A licensed pharmacies
- Third-party potency, sterility, and endotoxicity testing
- 48 states + Puerto Rico coverage
- B12/B6 + Glycine enhanced formulations
- No membership fees
Watch-outs
- Not available in Mississippi and Louisiana
- Compounded only — no brand-name options
- Site also promotes AI health optimization and longevity (broader platform)
Our Verdict
NewSelf edges out Metabolic Rx with a higher overall score of 8.3/10 and is particularly strong for lowest-cost compounded GLP-1 with pharmacy quality transparency. Metabolic Rx remains a solid alternative, especially if you're looking for people who want a flat price at every dose and can prepay for compounded semaglutide or tirzepatide.
Choose Metabolic Rx if…
You want people who want a flat price at every dose and can prepay for compounded semaglutide or tirzepatide and a starting price around $229/mo.
Choose NewSelf if…
You want lowest-cost compounded GLP-1 with pharmacy quality transparency and a starting price around $100/mo.
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Listed for disclosure only — see its FDA warning and BBB complaints first
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Get started →Maximus
Men seeking compounded GLP-1 alongside testosterone optimization
From $199.99/mo
Get started →Metabolic Rx vs NewSelf: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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