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Metabolic Rx vs Vytora Health

An in-depth comparison of two leading GLP-1 Providers

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By Eli Marsden · Founding Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed
Metabolic Rx logo

Metabolic Rx

6.3
★★★☆☆3.2/5

Best for: people who want a flat price at every dose and can prepay for compounded semaglutide or tirzepatide

Visit Metabolic Rx →
VS
Vytora Health logo

Vytora Health

8.4
★★★★☆4.2/5

Best for: compounded or brand-name GLP-1 with named pharmacy partners, 50 states

Visit Vytora Health →

Metabolic Rx and Vytora Health are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, Vytora Health starts lower at $150/mo versus $229/mo, and Vytora Health edges ahead overall (8.4 vs 6.3 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.

Pricing

Metabolic Rx

Monthly plan, weekly injection, charged every 30 daysCompounded
$259$159/mo
Save 39% right now
semaglutide

$159 first month, then $259. A 3-month plan is $449 and a 6-month plan $849, each charged upfront

Monthly plan, weekly injection, charged every 30 daysCompounded
$329$149/mo
Save 55% right now
tirzepatide

$149 first month, then $329. A 3-month plan is $597 and a 6-month plan $1,099, each charged upfront

Monthly plan, daily oral tablet, charged every 30 daysCompounded
$229$149/mo
Save 35% right now
semaglutide

$149 first month, then $229. Prepaid plans are shown at $166 a month for 3 months and $149 a month for 6 months

Vytora Health

All dosesCompounded
$180/mo
semaglutide
3-mo bundle ($450 billed)Compounded
$150/mo
semaglutide
All dosesCompounded
$249/mo
tirzepatide
3-mo bundle ($599 billed)Compounded
$200/mo
tirzepatide
Brand 5/7.5/10/12.5/15 mgBrand-name
$1399/mo
mounjaro
Brand 2.5/5/7.5/10/12.5/15 mgBrand-name
$1399/mo
zepbound

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What’s included

Metabolic Rx

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Included

Vytora Health

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

Score breakdown

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

Metabolic Rx

6.3/10

Overall

Vytora Health

8.4/10

Value25%

6.5A
vs
B
8.0

Effectiveness25%

8.0A
vs
B
8.5

User Experience15%

5.0A
vs
B
8.0

Trust & Safety15%

3.5A
vs
B
9.3

Accessibility10%

7.0A
vs
B
8.5

Support10%

7.0A
vs
B
8.4

Features & Coverage

FeatureMetabolic RxVytora Health
Starting Price$229/mo✓$150/mo
Features7 features✓8 features
States AvailableNot disclosed51
Compounded✓ Yes✓ Yes
Brand Name—✓ Yes
FSA/HSA Accepted——
FDA WarningsNoneNone

About Metabolic Rx

Metabolic Rx is a telehealth platform launched in 2026 that sells compounded semaglutide and tirzepatide injections and a daily oral semaglutide, with one flat price at every dose. Monthly plans renew at $259 for semaglutide and $329 for tirzepatide after a discounted first month of $159 or $149. The company does not name its medical group, pharmacies or the business behind it.

Read our full Metabolic Rx review →

About Vytora Health

Vytora Health is a 50-state-plus-DC telehealth platform offering compounded semaglutide and tirzepatide alongside brand-name Mounjaro and Zepbound, plus NAD+ and sermorelin peptides. It names its pharmacy partners publicly — Vials Pharmacy and Greenwich Biosciences — and discloses its operating physician group, uncommon transparency for the category. Compounded semaglutide runs $180/mo ($150 on a 3-month bundle) and tirzepatide $249/mo ($200 bundled).

Read our full Vytora Health review →

Pros & Cons

Metabolic Rx

What we like

  • One flat price at every dose, with medication, physician review, coaching and shipping included
  • Discounted first month: $159 for semaglutide and $149 for tirzepatide
  • Prepaying lowers semaglutide to about $142 to $150 a month and tirzepatide to $183 to $199 a month
  • Offers a daily oral semaglutide option as well as weekly injections
  • Refund if the prescribing clinician declines treatment or the order has not shipped
  • Publishes a support phone number with weekday hours

Watch-outs

  • The site does not name the company behind it, its medical group or the pharmacies that fill prescriptions
  • Its privacy policy lists a placeholder mailing address rather than a real one
  • Monthly plans renew at $259 for semaglutide and $329 for tirzepatide after the discounted first month
  • The intake says you are approved before any clinician reviews it, then runs a 15-minute countdown at checkout
  • You pay at checkout before a physician reviews your answers, and you must agree to calls and texts to continue
  • The 3- and 6-month plans are charged upfront, though checkout says you pay one month at a time
  • Its Trustpilot and Google rating badges could not be traced; there is no Trustpilot profile or LegitScript seal
  • The cancellation notice period is unclear: 48 hours in the terms but 30 days in the FAQ

Vytora Health

What we like

  • All 50 states plus DC, with per-state video-vs-audio compliance disclosed
  • Both compounded and brand-name options on one platform — uncommon
  • LegitScript Approved and HIPAA compliant
  • Pharmacy partners named publicly: Vials Pharmacy (TX) and Greenwich Biosciences
  • Operating entity disclosed: Wasef Health, PC (Pinellas Park, FL)
  • Competitive monthly pricing ($180 sema / $249 tirz) plus a 3-month bundle saving 17%
  • Brand-name Mounjaro and Zepbound available at $1,399/mo for FDA-approved options

Watch-outs

  • Brand-name Mounjaro/Zepbound at $1,399/mo is near retail — insured patients may do better via LillyDirect Self Pay ($449-$699/mo)
  • Compounded tirzepatide at $249/mo is mid-market, above the $149-199 floor
  • Dose tiers aren't broken out — 'all doses included' means low-dose patients pay the same as high-dose
  • Initial consultation cost not shown on the public pricing page
  • Limited per-prescriber state licensure detail

Our Verdict

Winner: Vytora Health

Vytora Health edges out Metabolic Rx with a higher overall score of 8.4/10 and is particularly strong for compounded or brand-name GLP-1 with named pharmacy partners, 50 states. Metabolic Rx remains a solid alternative, especially if you're looking for people who want a flat price at every dose and can prepay for compounded semaglutide or tirzepatide.

Choose Metabolic Rx if…

You want people who want a flat price at every dose and can prepay for compounded semaglutide or tirzepatide and a starting price around $229/mo.

Choose Vytora Health if…

You want compounded or brand-name GLP-1 with named pharmacy partners, 50 states and a starting price around $150/mo.

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7.4

MadeMed

Compounded GLP-1 in both injection and oral forms

8.3

Found

Mainstream telehealth GLP-1 access

8.1

Oak

Compounded semaglutide and tirzepatide at a flat monthly price

Metabolic Rx vs Vytora Health: FAQ

Vytora Health is cheaper. Its lowest ongoing monthly cash price is $150/mo, compared with $229/mo for Metabolic Rx. We compare standing (not first-month promo) prices so the figures reflect what you'd actually pay month to month.
Vytora Health scores higher overall at 8.4/10 versus 6.3/10, and is particularly strong for compounded or brand-name GLP-1 with named pharmacy partners, 50 states. That said, Metabolic Rx is a better fit if you want people who want a flat price at every dose and can prepay for compounded semaglutide or tirzepatide.
Vytora Health lists availability in 51 states, while Metabolic Rx's state list is not publicly listed.
Neither Metabolic Rx nor Vytora Health is currently an affiliate partner, so we earn no commission from either. We rank all providers editorially using the same six-dimension framework and disclose any commercial relationships.
For Semaglutide, Metabolic Rx is cheaper at $149/mo versus $150/mo at Vytora Health.

Key terms, explained

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Continue exploring Metabolic Rx and Vytora Health head-to-heads in the same category.

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Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.