MEDVi vs TMates
In our scoring, MEDVi edges ahead overall (7.1 vs 6.9 out of 10), and TMates costs less for compounded semaglutide (about $600 a year less).
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Key differences
- Price
- TMates $249/mo vs MEDVi $299/mo for compounded semaglutide (standing prices, no prepay or separate membership listed · about $600 a year less with TMates)
- Coverage
- MEDVi 48 states; TMates 50 states (only TMates: Mississippi and North Dakota)
- Included
- MEDVi: medication, clinician visits, shipping, coaching; TMates: medication, clinician visits, shipping, coaching
- Safety
- FDA warning letters on record: MEDVi 1, TMates none

MEDVi
Affiliate partnerBest for switching between compounded and brand-name GLP-1 through one provider
semaglutide
$299
$179 first month
Our score 7.1/10
TMates
Affiliate partnerBest for nationwide compounded GLP-1 availability including Puerto Rico
semaglutide
$249
Our score 6.9/10
We may earn a commission if you sign up through these links. Partner status can affect which provider we feature; it never changes a score or a price.
Costs & coverage
Published prices with their terms attached. Yearly figures are modeled from the standing price and billing cadence. A check mark marks the better side, on like-for-like rows only.
MEDVi
TMates
Price
Semaglutide / month
$299/mo
$179 first month
Better on this row: $249/mo
Semaglutide / year (modeled)
$3,588
Better on this row: $2,988
Tirzepatide / month
Not listed
$297/mo
Oral semaglutide / month
$249/mo
Not listed
Coverage
State availability
48 states
50 states
Oral option listed
Yes
Not listed
Included in the price
Medication, clinician visits, shipping, coaching
Medication, clinician visits, shipping, coaching
Terms & safety
Price shown
Before intake
Before intake
Lab work
Not required
Not disclosed
Video visit
Not required
Not disclosed
Cancel anytime
Not disclosed
Yes
Minimum commitment
Membership
None
FDA warning letters
1 warning letter
Better on this row: None on record
Provider facts checked
August 2026
August 2026
Show where they differ by stateHide state lists
Only TMates (2 states)
- Mississippi
- North Dakota
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Which fits your priorities?
Only the points where these two differ, from the table above and each provider’s record.

Choose MEDVi if…
- Lists oral compounded semaglutide, which TMates doesn't price
- Both compounded and brand-name (Wegovy, Zepbound) GLP-1 options in one platform
- Oral tablet and injectable formats
What to weigh up
- 1 FDA warning letter on record
- About $600 a year more than TMates for compounded semaglutide
Choose TMates if…
- About $600 a year less than MEDVi for compounded semaglutide at standing prices
- Lists compounded tirzepatide, which MEDVi doesn't price
- Serves Mississippi and North Dakota, where MEDVi doesn't
What to weigh up
- No third-party pharmacy accreditation (no LegitScript, PCAB, ACHC, or NABP)
- BBB rating of B+ (not accredited) with complaints centered on billing and cancellation
Explore the scoring factors
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
MEDVi
7.1/10
TMates
6.9/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Ready to start? Vetted GLP-1 providers
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Ivim Health
Compounded GLP-1 with weekly provider check-ins and health coaches, under a required monthly membership
Read full review →From $65/mo + membership
Get started →From $247/mo
Get started →From $139/mo
Get started →MEDVi vs TMates: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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Or see the full category ranking.
Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.