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Lttl vs TMates

In our scoring, Lttl edges ahead overall (7.2 vs 6.9 out of 10), and Lttl costs less for compounded semaglutide (about $1,701 a year less; one bills every 4 weeks (13 charges a year), so this compares modeled yearly cost).

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By Eli Marsden · Founding Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed

Key differences

Price
Lttl $99/mo vs TMates $249/mo for compounded semaglutide (standing prices, no prepay or separate membership listed · about $1,701 a year less with Lttl · one bills every 4 weeks (13 charges a year), so this compares modeled yearly cost)
Coverage
TMates 50 states (Lttl doesn't publish a state list)
Included
Lttl: medication, clinician visits, shipping; TMates: medication, clinician visits, shipping, coaching

How we compare providers

Lttl logo

Lttl

Affiliate partner

Best for every commitment tier priced openly, plus a low-dose microdose option

semaglutide

$99/mo

billed every 4 weeks

Our score 7.2/10

Visit siteRead review
TMates logo

TMates

Affiliate partner

Best for nationwide compounded GLP-1 availability including Puerto Rico

semaglutide

$249/mo

Our score 6.9/10

Visit siteRead review

We may earn a commission if you sign up through these links. Partner status can affect which provider we feature; it never changes a score or a price.

Costs & coverage

Published prices with their terms attached. Yearly figures are modeled from the standing price and billing cadence. A check mark marks the better side, on like-for-like rows only.

Lttl

TMates

Price

Semaglutide / month

Better on this row: $99/mo

billed every 4 weeks

$249/mo

Semaglutide / year (modeled)

Better on this row: $1,287

13 charges

$2,988

Tirzepatide / month

Better on this row: $149/mo

billed every 4 weeks

$297/mo

Tirzepatide / year (modeled)

Better on this row: $1,937

13 charges

$3,564

Oral semaglutide / month

$179/mo

$149 first month

Not listed

Coverage

State availability

List not published

50 states

Oral option listed

Yes

Not listed

Included in the price

Medication, clinician visits, shipping

Medication, clinician visits, shipping, coaching

FSA/HSA accepted

Yes

Not listed

Terms & safety

Price shown

Before intake

Before intake

Cancel anytime

Yes

Yes

Minimum commitment

None on the monthly plan; 3-, 6- and 12-month prepay tiers offered at lower per-month rates

None

FDA warning letters

None on record

None on record

Provider facts checked

October 2026

August 2026

Every dose and plan: Lttl · TMates

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Which fits your priorities?

Only the points where these two differ, from the table above and each provider’s record.

Lttl logo

Choose Lttl if…

  • About $1,701 a year less than TMates for compounded semaglutide at standing prices (one bills every 4 weeks (13 charges a year), so this compares modeled yearly cost)
  • Lists oral compounded semaglutide, which TMates doesn't price
  • Accepts FSA/HSA cards

What to weigh up

  • No published state list; confirm yours at signup
  • Partner pharmacies are never named — the site refers only to 'a partner U.S. pharmacy' (a material disclosure gap for a YMYL purchase)
Visit LttlRead the full Lttl review
TMates logo

Choose TMates if…

  • Publishes its full state list (50 states)
  • All-inclusive monthly price covers medication, consults, nutrition coaching, and 24/7 support — no separate membership fee
  • Fast stated turnaround — 2–3 days from intake to delivery

What to weigh up

  • About $1,701 a year more than Lttl for compounded semaglutide (one bills every 4 weeks (13 charges a year), so this compares modeled yearly cost)
  • No third-party pharmacy accreditation (no LegitScript, PCAB, ACHC, or NABP)
Visit TMatesRead the full TMates review

Explore the scoring factors

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

Lttl

7.2/10

Overall

TMates

6.9/10

Value25%

7.0A
vs
B
6.5

Effectiveness25%

7.5A
vs
B
7.5

User Experience15%

8.0A
vs
B
8.0

Trust & Safety15%

6.5A
vs
B
5.3

Accessibility10%

6.5A
vs
B
7.5

Support10%

7.0A
vs
B
6.5

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Lttl vs TMates: FAQ

For compounded semaglutide, Lttl costs less: about $1,701 less a year at the standing price, with no prepay or separate membership listed (not a first-month promo); one bills every 4 weeks (13 charges a year), so this compares modeled yearly cost. See Costs & coverage above for each medication side by side.
Lttl scores higher overall at 7.2/10 versus 6.9/10, and is particularly strong for every commitment tier priced openly, plus a low-dose microdose option. That said, TMates is a better fit if you want nationwide compounded GLP-1 availability including Puerto Rico.
Both Lttl and TMates are affiliate partners, meaning we may earn a commission if you sign up through our links. Our scores are assigned editorially using the same six-dimension framework for every provider — partnership never changes a score. We disclose every commercial relationship.
Lttl: $99 (billed every 4 weeks, 13 charges a year), about $1,287 a year. TMates: $249, about $2,988 a year. Lttl costs about $1,701 less a year at these prices.
Lttl doesn't publish a state list. TMates publishes 50 states. Where a list isn't published, confirm your state during sign-up before paying.
Lttl: cancel anytime — yes; minimum commitment — None on the monthly plan; 3-, 6- and 12-month prepay tiers offered at lower per-month rates; early-cancellation fee — not disclosed. TMates: cancel anytime — yes; minimum commitment — None; early-cancellation fee — not disclosed. Check the provider's own terms before you buy.

Key terms, explained

New to GLP-1s? Tap any term for a quick, plain-English definition.

Related comparisons

Continue exploring Lttl and TMates head-to-heads in the same category.

Or see the full category ranking.

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