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Lean Meds vs NewSelf

An in-depth comparison of two leading GLP-1 Providers

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By Eli Marsden · Founding Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed
Lean Meds logo

Lean Meds

7.6
★★★★☆3.8/5

Best for: a flat monthly GLP-1 price that never rises with your dose, from a service that names its pharmacies

Visit Lean Meds →
VS
NewSelf logo

NewSelf

8.3
★★★★☆4.2/5

Best for: lowest-cost compounded GLP-1 with pharmacy quality transparency

Visit NewSelf →

Lean Meds and NewSelf are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, Lean Meds starts lower at $49/mo versus $100/mo, and NewSelf edges ahead overall (8.3 vs 7.6 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.

Pricing

Lean Meds

Starting price, any dose — molecule not namedCompounded
$49/mo

The hero reads 'Starting at $49/mo — Same price every month, first order & every order after'. It is the only figure on the site and names no medication; the per-plan prices appear only past the date-of-birth screen of the quiz.

NewSelf

Semaglutide+ (best price)Compounded
$100/mo
semaglutide

All dosages same price

Semaglutide+ (regular)Compounded
$135/mo
semaglutide
Tirzepatide+ (best price)Compounded
$144/mo
tirzepatide

All dosages same price

Tirzepatide+ (regular)Compounded
$225/mo
tirzepatide

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What’s included

Lean Meds

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

NewSelf

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

Score breakdown

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

Lean Meds

7.6/10

Overall

NewSelf

8.3/10

Value25%

8.0A
vs
B
9.0

Effectiveness25%

7.5A
vs
B
8.0

User Experience15%

7.5A
vs
B
8.0

Trust & Safety15%

7.0A
vs
B
8.3

Accessibility10%

8.5A
vs
B
8.5

Support10%

7.0A
vs
B
7.9

Features & Coverage

FeatureLean MedsNewSelf
Starting Price✓$49/mo$100/mo
Features✓7 features6 features
States Available✓5049
Compounded✓ Yes✓ Yes
Brand Name——
FSA/HSA Accepted——
FDA Warnings✓None1 warning

About Lean Meds

Lean Meds is a compounded GLP-1 telehealth storefront whose Terms name OpenLoop Health, Inc. as the operator, with medical care delivered by OpenLoop Healthcare Partners, PC. It charges one flat monthly rate that does not rise as your dose increases, and it names four dispensing pharmacies. The only public figure is 'Starting at $49/mo', and it is tied to no named medication — the per-plan prices sit behind a date-of-birth gate. Free shipping and the telehealth visit are included.

Read our full Lean Meds review →

About NewSelf

NewSelf offers compounded semaglutide+ (with B12/Glycine, from $99.97/mo) and compounded tirzepatide+ (with B6/Glycine, from $144.49/mo). LegitScript certified. Available in 48 states + Puerto Rico. Uses 503A licensed pharmacies with third-party testing.

Read our full NewSelf review →

Pros & Cons

Lean Meds

What we like

  • One flat monthly price that does not increase as your dose is titrated up
  • Names four dispensing pharmacies with addresses and phone numbers: RedRock, Health Warehouse, Precision Medicine and Triad Rx
  • Every plan adds a 1:1 care coach and a US-licensed registered nutritionist at no separate charge
  • The monthly rate includes the telehealth visit and free shipping, with typical delivery in 4 to 5 business days
  • Month-to-month with no contract, and available in all 50 states

Watch-outs

  • The only public figure is 'Starting at $49/mo', which names no medication; per-plan prices sit behind a date-of-birth gate
  • The footer Pricing link points at an anchor that does not exist, and the membership plans page the FAQ cites is not linked anywhere
  • The LegitScript link goes to the generic lookup form with no seal ID, so the link doesn't prove certification
  • All payments are final and non-refundable at purchase; medical disqualification is the only exception
  • The Terms ask for 48 hours' notice to cancel while the refund policy asks for 72 hours before the next billing date
  • The hero promises 'No auto rebill' while the Terms describe automatic recurring charges
  • The hero says 'Eligible for Insurance' while the FAQ calls it a self-pay service and the Terms bar reimbursement

NewSelf

What we like

  • Semaglutide+ from $99.97/mo — among the lowest prices in the dataset
  • All dosages at the same price — no price escalation as dose increases
  • LegitScript certified with 503A licensed pharmacies
  • Third-party potency, sterility, and endotoxicity testing
  • 48 states + Puerto Rico coverage
  • B12/B6 + Glycine enhanced formulations
  • No membership fees

Watch-outs

  • Not available in Mississippi and Louisiana
  • Compounded only — no brand-name options
  • Site also promotes AI health optimization and longevity (broader platform)

Our Verdict

Winner: NewSelf

NewSelf edges out Lean Meds with a higher overall score of 8.3/10 and is particularly strong for lowest-cost compounded GLP-1 with pharmacy quality transparency. Lean Meds remains a solid alternative, especially if you're looking for a flat monthly GLP-1 price that never rises with your dose, from a service that names its pharmacies.

Choose Lean Meds if…

You want a flat monthly GLP-1 price that never rises with your dose, from a service that names its pharmacies and a starting price around $49/mo.

Choose NewSelf if…

You want lowest-cost compounded GLP-1 with pharmacy quality transparency and a starting price around $100/mo.

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7.8

Care Bare Rx

LGBTQ+-inclusive compounded GLP-1 telehealth

8.2

Enhance MD

Lab-monitored compounded GLP-1 with mandatory video visit

7.1

MEDVi

Switching between compounded and brand-name GLP-1 through one provider

Lean Meds vs NewSelf: FAQ

Lean Meds is cheaper. Its lowest ongoing monthly cash price is $49/mo, compared with $100/mo for NewSelf. We compare standing (not first-month promo) prices so the figures reflect what you'd actually pay month to month.
NewSelf scores higher overall at 8.3/10 versus 7.6/10, and is particularly strong for lowest-cost compounded GLP-1 with pharmacy quality transparency. That said, Lean Meds is a better fit if you want a flat monthly GLP-1 price that never rises with your dose, from a service that names its pharmacies.
Lean Meds covers more — 50 states versus 49.
Neither Lean Meds nor NewSelf is currently an affiliate partner, so we earn no commission from either. We rank all providers editorially using the same six-dimension framework and disclose any commercial relationships.

Key terms, explained

New to GLP-1s? Tap any term for a quick, plain-English definition.

Continue exploring Lean Meds and NewSelf head-to-heads in the same category.

Or see the full category ranking.

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