Lean Rx vs NewSelf
An in-depth comparison of two leading GLP-1 Providers
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Lean Rx
Best for: Patients wanting compounded GLP-1 in injectable, sublingual, or tablet form
Visit Lean Rx →
NewSelf
Best for: lowest-cost compounded GLP-1 with pharmacy quality transparency
Visit NewSelf →Lean Rx and NewSelf are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, NewSelf starts lower at $100/mo versus $266/mo, and NewSelf edges ahead overall (8.3 vs 6.8 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.
Pricing
Lean Rx
NewSelf
All dosages same price
All dosages same price
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What’s included
Lean Rx
What the monthly price covers
Medication
Included
Provider visits
Not disclosed
Shipping
Not disclosed
Lab work
Not disclosed
Coaching
Not disclosed
NewSelf
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Included
Lab work
Not disclosed
Coaching
Not disclosed
Score breakdown
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
Lean Rx
6.8/10
NewSelf
8.3/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Features & Coverage
| Feature | Lean Rx | NewSelf |
|---|---|---|
| Starting Price | $266/mo | ✓$100/mo |
| Features | ✓8 features | 6 features |
| States Available | Not disclosed | 49 |
| Compounded | ✓ Yes | ✓ Yes |
| Brand Name | — | — |
| FSA/HSA Accepted | — | — |
| FDA Warnings | None | None |
About Lean Rx
Lean Rx is a Sacramento-based telehealth technology platform offering compounded GLP-1 weight loss medications. Patients complete an online medical history and a telehealth call with an independent licensed provider, who prescribes when appropriate, then receive medication shipped home. Lean Rx offers compounded semaglutide from $266 per month and tirzepatide from $399 per month, in injectable, sublingual, and tablet forms. It advertises upfront pricing with no hidden fees, and notes it is a technology platform, not a healthcare provider. No state list is published.
Read our full Lean Rx review →About NewSelf
NewSelf offers compounded semaglutide+ (with B12/Glycine, from $99.97/mo) and compounded tirzepatide+ (with B6/Glycine, from $144.49/mo). LegitScript certified. Available in 48 states + Puerto Rico. Uses 503A licensed pharmacies with third-party testing.
Read our full NewSelf review →Pros & Cons
Lean Rx
What we like
- Both semaglutide and tirzepatide offered
- Three formulations: injectable, sublingual, and tablet
- Upfront pricing with no hidden fees advertised
- Semaglutide starts at a low $266/month
- Telehealth call with a licensed provider before prescribing
Watch-outs
- Compounded-only; no FDA-approved branded options
- No published state availability list
- Platform is technology only, not a healthcare provider itself
- Provider credentials not detailed on site
NewSelf
What we like
- Semaglutide+ from $99.97/mo — among the lowest prices in the dataset
- All dosages at the same price — no price escalation as dose increases
- LegitScript certified with 503A licensed pharmacies
- Third-party potency, sterility, and endotoxicity testing
- 48 states + Puerto Rico coverage
- B12/B6 + Glycine enhanced formulations
- No membership fees
Watch-outs
- Not available in Mississippi and Louisiana
- Compounded only — no brand-name options
- Site also promotes AI health optimization and longevity (broader platform)
Our Verdict
NewSelf edges out Lean Rx with a higher overall score of 8.3/10 and is particularly strong for lowest-cost compounded GLP-1 with pharmacy quality transparency. Lean Rx remains a solid alternative, especially if you're looking for Patients wanting compounded GLP-1 in injectable, sublingual, or tablet form.
Choose Lean Rx if…
You want Patients wanting compounded GLP-1 in injectable, sublingual, or tablet form and a starting price around $266/mo.
Choose NewSelf if…
You want lowest-cost compounded GLP-1 with pharmacy quality transparency and a starting price around $100/mo.
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Trimi Health
Budget-conscious shoppers
From $99/mo
Get started →ShedRx
Mainstream telehealth GLP-1 access
From $149/mo
Get started →bmiMD
Mainstream telehealth GLP-1 access
From $99/mo
Get started →Lean Rx vs NewSelf: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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Or see the full category ranking.
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