Lean Rx vs Vytora Health
In our scoring, Vytora Health edges ahead overall (8.4 vs 6.8 out of 10), and Vytora Health costs less for compounded semaglutide (about $1,440 a year less).
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Key differences
- Price
- Vytora Health $179/mo vs Lean Rx $299/mo for compounded semaglutide (standing prices, no prepay or separate membership listed · about $1,440 a year less with Vytora Health)
- Coverage
- Vytora Health 50 states + DC (Lean Rx doesn't publish a state list)
- Included
- Lean Rx: medication; Vytora Health: medication, clinician visits, shipping
Lean Rx
Best for Patients wanting compounded GLP-1 in injectable, sublingual, or tablet form
semaglutide
$299
$266 first month
Our score 6.8/10
Vytora Health
Best for compounded or brand-name GLP-1 with named pharmacy partners, 50 states
semaglutide
$179
Our score 8.4/10
We may earn a commission if you sign up through these links. Partner status can affect which provider we feature; it never changes a score or a price.
Costs & coverage
Published prices with their terms attached. Yearly figures are modeled from the standing price and billing cadence. A check mark marks the better side, on like-for-like rows only.
Lean Rx
Vytora Health
Price
Semaglutide / month
$299/mo
$266 first month
Better on this row: $179/mo
Semaglutide / year (modeled)
$3,588
Better on this row: $2,148
Tirzepatide / month
$449/mo
$399 first month
Better on this row: $249/mo
Tirzepatide / year (modeled)
$5,388
Better on this row: $2,988
Brand Zepbound / Mounjaro / month
Not listed
$1,399/mo
Coverage
State availability
List not published
50 states + DC
Brand-name access listed
Not listed
Zepbound / Mounjaro
Included in the price
Medication
Medication, clinician visits, shipping
Terms & safety
Price shown
Before intake
Before intake
Video visit
Required
Not disclosed
Cancel anytime
Not disclosed
Yes
Minimum commitment
Not disclosed
None on monthly plans; 3-month plans are billed every 3 months
Refunds
Not disclosed
'All sales are final' for prescription products; refund requests 'reviewed on a case-by-case basis'
FDA warning letters
None on record
None on record
Provider facts checked
August 2026
October 2026
Every dose and plan: Lean Rx · Vytora Health
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Which fits your priorities?
Only the points where these two differ, from the table above and each provider’s record.
Choose Lean Rx if…
- Three formulations: injectable, sublingual, and tablet
- Upfront pricing with no hidden fees advertised
- Telehealth call with a licensed provider before prescribing
What to weigh up
- About $1,440 a year more than Vytora Health for compounded semaglutide
- No published state list; confirm yours at signup
Choose Vytora Health if…
- About $1,440 a year less than Lean Rx for compounded semaglutide at standing prices
- Lists brand-name Zepbound / Mounjaro, which Lean Rx doesn't price
- Publishes its full state list (50 states + DC)
What to weigh up
- Brand-name Mounjaro and Zepbound at $1,399/mo are priced at retail; manufacturer self-pay programs are often cheaper
- Compounded tirzepatide at $249/mo month-to-month is mid-market
Explore the scoring factors
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
Lean Rx
6.8/10
Vytora Health
8.4/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Ready to start? Vetted GLP-1 providers
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From $139/mo
Get started →From $299/mo
Get started →SkinnyRx
Compounded semaglutide or tirzepatide with the consult and free overnight shipping in one price
Read full review →From $149.25/mo
Get started →Lean Rx vs Vytora Health: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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- Vytora Health vs Collective
Or see the full category ranking.
Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.