KairoRx vs NewSelf
An in-depth comparison of two leading GLP-1 Providers
WeightLossRankings.org is reader-supported. When you buy through links on our site, we may earn an affiliate commission. Learn more

KairoRx
Best for: people who want compounded GLP-1s alongside peptide and hormone treatments from one telehealth brand
Visit KairoRx →
NewSelf
Best for: lowest-cost compounded GLP-1 with pharmacy quality transparency
Visit NewSelf →KairoRx and NewSelf are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, NewSelf starts lower at $100/mo versus $199/mo, and NewSelf edges ahead overall (8.3 vs 6.4 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.
Pricing
KairoRx
$49 first month, then $199 a month. A quarterly plan is listed at $747 per quarter ($249 a month)
$99 first month, then $349 a month. A quarterly plan is listed at $897 per quarter ($299 a month)
$65 a month covers the provider review, titration and care-team support; the pharmacy bills the medication on top
$65 a month covers the provider review, titration and care-team support; the pharmacy bills the medication on top
NewSelf
All dosages same price
All dosages same price
Get alerted when GLP-1 prices drop
Join the GLP-1 price-watch list — we re-verify 540+ providers' prices on their own sites and email you when tracked prices move.
What’s included
KairoRx
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Included
Lab work
Not disclosed
Coaching
Included
NewSelf
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Included
Lab work
Not disclosed
Coaching
Not disclosed
Score breakdown
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
KairoRx
6.4/10
NewSelf
8.3/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Features & Coverage
| Feature | KairoRx | NewSelf |
|---|---|---|
| Starting Price | $199/mo | ✓$100/mo |
| Features | ✓8 features | 6 features |
| States Available | Not disclosed | 49 |
| Compounded | ✓ Yes | ✓ Yes |
| Brand Name | ✓ Yes | — |
| FSA/HSA Accepted | ✓ Yes | — |
| FDA Warnings | ✓None | 1 warning |
About KairoRx
KairoRx is a telehealth brand launched in 2026 that lists compounded semaglutide and tirzepatide alongside peptide, hormone and longevity treatments. Its pricing page shows semaglutide at $49 for the first month, then $199 a month, and tirzepatide at $99, then $349 a month. The online form ends with a promise of follow-up rather than a checkout, and the company does not name its medical group or pharmacies.
Read our full KairoRx review →About NewSelf
NewSelf offers compounded semaglutide+ (with B12/Glycine, from $99.97/mo) and compounded tirzepatide+ (with B6/Glycine, from $144.49/mo). LegitScript certified. Available in 48 states + Puerto Rico. Uses 503A licensed pharmacies with third-party testing.
Read our full NewSelf review →Pros & Cons
KairoRx
What we like
- Compounded semaglutide and tirzepatide prices are listed on the site before you start
- You are not charged until a provider approves a plan, according to its terms and FAQ
- Compounded plans include provider messaging, coaching and free shipping, with no membership fee
- Brand-name Ozempic and Zepbound are available for a $65 monthly access fee plus the medication cost
- Full refund if you cancel within 14 days of the first charge and the pharmacy has not yet prepared your order
- Publishes a support phone number, and HSA or FSA cards are accepted
Watch-outs
- The site does not name the company behind it, its medical group or the pharmacies that fill prescriptions
- The online form ends with a promise that the team will follow up by email or text, with no plan choice or checkout
- The weight-loss page shows different prices ($149 injections, $99 brand membership) that it calls illustrative
- After the $49 or $99 first month, semaglutide renews at $199 and tirzepatide at $349 a month
- The quarterly semaglutide plan costs $249 a month, more than the $199 monthly plan it is promoted against
- The site launched in 2026 yet claims 12,000+ members, a 4.8 rating and press coverage we could not trace
- There is no Trustpilot profile and no LegitScript certification
- The list of states it serves is not published
NewSelf
What we like
- Semaglutide+ from $99.97/mo — among the lowest prices in the dataset
- All dosages at the same price — no price escalation as dose increases
- LegitScript certified with 503A licensed pharmacies
- Third-party potency, sterility, and endotoxicity testing
- 48 states + Puerto Rico coverage
- B12/B6 + Glycine enhanced formulations
- No membership fees
Watch-outs
- Not available in Mississippi and Louisiana
- Compounded only — no brand-name options
- Site also promotes AI health optimization and longevity (broader platform)
Our Verdict
NewSelf edges out KairoRx with a higher overall score of 8.3/10 and is particularly strong for lowest-cost compounded GLP-1 with pharmacy quality transparency. KairoRx remains a solid alternative, especially if you're looking for people who want compounded GLP-1s alongside peptide and hormone treatments from one telehealth brand.
Choose KairoRx if…
You want people who want compounded GLP-1s alongside peptide and hormone treatments from one telehealth brand and a starting price around $199/mo.
Choose NewSelf if…
You want lowest-cost compounded GLP-1 with pharmacy quality transparency and a starting price around $100/mo.
Ready to start? Vetted GLP-1 providers
Vetted telehealth providers that prescribe GLP-1 online.
No insurance needed · vetted by our editors
WeightLossRankings.org is reader-supported. When you buy through links on our site, we may earn an affiliate commission. Learn more
Direct Meds
Listed for disclosure only — see its FDA warning and BBB complaints first
From $249/mo
Get started →Maximus
Men seeking compounded GLP-1 alongside testosterone optimization
From $199.99/mo
Get started →Sesame Care
Brand-name GLP-1s at cash prices, no compounding
From $25/mo
Get started →KairoRx vs NewSelf: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
Related comparisons
Continue exploring KairoRx and NewSelf head-to-heads in the same category.
- KairoRx vs Amazon One Medical
- KairoRx vs Vytora Health
- KairoRx vs Collective
- NewSelf vs CoreAge Rx
- NewSelf vs EverSlim
- NewSelf vs Found
Or see the full category ranking.
Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.