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KairoRx vs NewSelf

An in-depth comparison of two leading GLP-1 Providers

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By Eli Marsden · Founding Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed
KairoRx logo

KairoRx

6.4
★★★☆☆3.2/5

Best for: people who want compounded GLP-1s alongside peptide and hormone treatments from one telehealth brand

Visit KairoRx →
VS
NewSelf logo

NewSelf

8.3
★★★★☆4.2/5

Best for: lowest-cost compounded GLP-1 with pharmacy quality transparency

Visit NewSelf →

KairoRx and NewSelf are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, NewSelf starts lower at $100/mo versus $199/mo, and NewSelf edges ahead overall (8.3 vs 6.4 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.

Pricing

KairoRx

Monthly plan, weekly injection, billed monthlyCompounded
$199$49/mo
Save 75% right now
semaglutide

$49 first month, then $199 a month. A quarterly plan is listed at $747 per quarter ($249 a month)

Monthly plan, weekly injection, billed monthlyCompounded
$349$99/mo
Save 72% right now
tirzepatide

$99 first month, then $349 a month. A quarterly plan is listed at $897 per quarter ($299 a month)

Ozempic access fee (medication billed separately)Brand-name
$65/mo
semaglutide

$65 a month covers the provider review, titration and care-team support; the pharmacy bills the medication on top

Zepbound access fee (medication billed separately)Brand-name
$65/mo
tirzepatide

$65 a month covers the provider review, titration and care-team support; the pharmacy bills the medication on top

NewSelf

Semaglutide+ (best price)Compounded
$100/mo
semaglutide

All dosages same price

Semaglutide+ (regular)Compounded
$135/mo
semaglutide
Tirzepatide+ (best price)Compounded
$144/mo
tirzepatide

All dosages same price

Tirzepatide+ (regular)Compounded
$225/mo
tirzepatide

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What’s included

KairoRx

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Included

NewSelf

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

Score breakdown

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

KairoRx

6.4/10

Overall

NewSelf

8.3/10

Value25%

7.0A
vs
B
9.0

Effectiveness25%

8.0A
vs
B
8.0

User Experience15%

5.0A
vs
B
8.0

Trust & Safety15%

4.0A
vs
B
8.3

Accessibility10%

6.5A
vs
B
8.5

Support10%

6.5A
vs
B
7.9

Features & Coverage

FeatureKairoRxNewSelf
Starting Price$199/mo✓$100/mo
Features✓8 features6 features
States AvailableNot disclosed49
Compounded✓ Yes✓ Yes
Brand Name✓ Yes—
FSA/HSA Accepted✓ Yes—
FDA Warnings✓None1 warning

About KairoRx

KairoRx is a telehealth brand launched in 2026 that lists compounded semaglutide and tirzepatide alongside peptide, hormone and longevity treatments. Its pricing page shows semaglutide at $49 for the first month, then $199 a month, and tirzepatide at $99, then $349 a month. The online form ends with a promise of follow-up rather than a checkout, and the company does not name its medical group or pharmacies.

Read our full KairoRx review →

About NewSelf

NewSelf offers compounded semaglutide+ (with B12/Glycine, from $99.97/mo) and compounded tirzepatide+ (with B6/Glycine, from $144.49/mo). LegitScript certified. Available in 48 states + Puerto Rico. Uses 503A licensed pharmacies with third-party testing.

Read our full NewSelf review →

Pros & Cons

KairoRx

What we like

  • Compounded semaglutide and tirzepatide prices are listed on the site before you start
  • You are not charged until a provider approves a plan, according to its terms and FAQ
  • Compounded plans include provider messaging, coaching and free shipping, with no membership fee
  • Brand-name Ozempic and Zepbound are available for a $65 monthly access fee plus the medication cost
  • Full refund if you cancel within 14 days of the first charge and the pharmacy has not yet prepared your order
  • Publishes a support phone number, and HSA or FSA cards are accepted

Watch-outs

  • The site does not name the company behind it, its medical group or the pharmacies that fill prescriptions
  • The online form ends with a promise that the team will follow up by email or text, with no plan choice or checkout
  • The weight-loss page shows different prices ($149 injections, $99 brand membership) that it calls illustrative
  • After the $49 or $99 first month, semaglutide renews at $199 and tirzepatide at $349 a month
  • The quarterly semaglutide plan costs $249 a month, more than the $199 monthly plan it is promoted against
  • The site launched in 2026 yet claims 12,000+ members, a 4.8 rating and press coverage we could not trace
  • There is no Trustpilot profile and no LegitScript certification
  • The list of states it serves is not published

NewSelf

What we like

  • Semaglutide+ from $99.97/mo — among the lowest prices in the dataset
  • All dosages at the same price — no price escalation as dose increases
  • LegitScript certified with 503A licensed pharmacies
  • Third-party potency, sterility, and endotoxicity testing
  • 48 states + Puerto Rico coverage
  • B12/B6 + Glycine enhanced formulations
  • No membership fees

Watch-outs

  • Not available in Mississippi and Louisiana
  • Compounded only — no brand-name options
  • Site also promotes AI health optimization and longevity (broader platform)

Our Verdict

Winner: NewSelf

NewSelf edges out KairoRx with a higher overall score of 8.3/10 and is particularly strong for lowest-cost compounded GLP-1 with pharmacy quality transparency. KairoRx remains a solid alternative, especially if you're looking for people who want compounded GLP-1s alongside peptide and hormone treatments from one telehealth brand.

Choose KairoRx if…

You want people who want compounded GLP-1s alongside peptide and hormone treatments from one telehealth brand and a starting price around $199/mo.

Choose NewSelf if…

You want lowest-cost compounded GLP-1 with pharmacy quality transparency and a starting price around $100/mo.

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6.4

Direct Meds

Listed for disclosure only — see its FDA warning and BBB complaints first

7.6

Maximus

Men seeking compounded GLP-1 alongside testosterone optimization

8.0

Sesame Care

Brand-name GLP-1s at cash prices, no compounding

KairoRx vs NewSelf: FAQ

NewSelf is cheaper. Its lowest ongoing monthly cash price is $100/mo, compared with $199/mo for KairoRx. We compare standing (not first-month promo) prices so the figures reflect what you'd actually pay month to month.
NewSelf scores higher overall at 8.3/10 versus 6.4/10, and is particularly strong for lowest-cost compounded GLP-1 with pharmacy quality transparency. That said, KairoRx is a better fit if you want people who want compounded GLP-1s alongside peptide and hormone treatments from one telehealth brand.
NewSelf lists availability in 49 states, while KairoRx's state list is not publicly listed.
Neither KairoRx nor NewSelf is currently an affiliate partner, so we earn no commission from either. We rank all providers editorially using the same six-dimension framework and disclose any commercial relationships.
For Semaglutide, KairoRx is cheaper at $49/mo versus $100/mo at NewSelf.

Key terms, explained

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Continue exploring KairoRx and NewSelf head-to-heads in the same category.

Or see the full category ranking.

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