KairoRx vs Amazon One Medical
An in-depth comparison of two leading GLP-1 Providers
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KairoRx
Best for: people who want compounded GLP-1s alongside peptide and hormone treatments from one telehealth brand
Visit KairoRx →
Amazon One Medical
Best for: the most authoritative brand-name GLP-1 channel, with same-day delivery
Visit Amazon One Medical →KairoRx and Amazon One Medical are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, Amazon One Medical starts lower at $149/mo versus $199/mo, and Amazon One Medical edges ahead overall (8.5 vs 6.4 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.
Pricing
KairoRx
$49 first month, then $199 a month. A quarterly plan is listed at $747 per quarter ($249 a month)
$99 first month, then $349 a month. A quarterly plan is listed at $897 per quarter ($299 a month)
$65 a month covers the provider review, titration and care-team support; the pharmacy bills the medication on top
$65 a month covers the provider review, titration and care-team support; the pharmacy bills the medication on top
Amazon One Medical
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What’s included
KairoRx
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Included
Lab work
Not disclosed
Coaching
Included
Amazon One Medical
What the monthly price covers
Medication
Billed separately
Provider visits
Included
Shipping
Included
Lab work
Billed separately
Coaching
Not disclosed
Score breakdown
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
KairoRx
6.4/10
Amazon One Medical
8.5/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Features & Coverage
| Feature | KairoRx | Amazon One Medical |
|---|---|---|
| Starting Price | $199/mo | ✓$149/mo |
| Features | ✓8 features | 6 features |
| States Available | Not disclosed | 50 |
| Compounded | ✓ Yes | — |
| Brand Name | ✓ Yes | ✓ Yes |
| FSA/HSA Accepted | ✓ Yes | — |
| FDA Warnings | None | None |
About KairoRx
KairoRx is a telehealth brand launched in 2026 that lists compounded semaglutide and tirzepatide alongside peptide, hormone and longevity treatments. Its pricing page shows semaglutide at $49 for the first month, then $199 a month, and tirzepatide at $99, then $349 a month. The online form ends with a promise of follow-up rather than a checkout, and the company does not name its medical group or pharmacies.
Read our full KairoRx review →About Amazon One Medical
Amazon One Medical is the unified Amazon GLP-1 channel — One Medical clinicians prescribe FDA-approved Wegovy, Zepbound, and Foundayo (no compounded products), and Amazon Pharmacy fulfills with same-day delivery across roughly 3,000 US cities plus pickup kiosks at select One Medical locations. No prior membership required; insurance and cash pay both accepted. Foundayo launched at $25/month with insurance and the Lilly Savings Card, or $149/month cash pay.
Read our full Amazon One Medical review →Pros & Cons
KairoRx
What we like
- Compounded semaglutide and tirzepatide prices are listed on the site before you start
- You are not charged until a provider approves a plan, according to its terms and FAQ
- Compounded plans include provider messaging, coaching and free shipping, with no membership fee
- Brand-name Ozempic and Zepbound are available for a $65 monthly access fee plus the medication cost
- Full refund if you cancel within 14 days of the first charge and the pharmacy has not yet prepared your order
- Publishes a support phone number, and HSA or FSA cards are accepted
Watch-outs
- The site does not name the company behind it, its medical group or the pharmacies that fill prescriptions
- The online form ends with a promise that the team will follow up by email or text, with no plan choice or checkout
- The weight-loss page shows different prices ($149 injections, $99 brand membership) that it calls illustrative
- After the $49 or $99 first month, semaglutide renews at $199 and tirzepatide at $349 a month
- The quarterly semaglutide plan costs $249 a month, more than the $199 monthly plan it is promoted against
- The site launched in 2026 yet claims 12,000+ members, a 4.8 rating and press coverage we could not trace
- There is no Trustpilot profile and no LegitScript certification
- The list of states it serves is not published
Amazon One Medical
What we like
- As low as $1/day ($25/month) for brand-name Foundayo with insurance and the auto-applied Lilly coupon
- Same-day delivery in nearly 3,000 US cities at launch, expanding to 4,500 by end of 2026
- In-office pharmacist kiosks at select One Medical clinics let you walk out with Foundayo in hand
- Cash-pay $5/day ($149/month) is competitive for the same FDA-approved brand-name product
- Real-time availability, transparent pricing, and automatic manufacturer coupon at checkout
- Delivering GLP-1 medications since 2021 — track record on cold-chain logistics
Watch-outs
- Headline $25/month needs both insurance and the Lilly Savings Card — uninsured pay $149/month
- Same-day delivery is geographically gated; outside major cities it drops to next-day or slower
- Pricing is set by manufacturer savings programs and can change at any time
- No compounded options — brand-name only (Foundayo, Wegovy, Zepbound)
- Wegovy/Zepbound pricing isn't shown upfront — depends on insurance at the prescribing visit
- Copays and deductibles still apply to the clinical visit
Our Verdict
Amazon One Medical edges out KairoRx with a higher overall score of 8.5/10 and is particularly strong for the most authoritative brand-name GLP-1 channel, with same-day delivery. KairoRx remains a solid alternative, especially if you're looking for people who want compounded GLP-1s alongside peptide and hormone treatments from one telehealth brand.
Choose KairoRx if…
You want people who want compounded GLP-1s alongside peptide and hormone treatments from one telehealth brand and a starting price around $199/mo.
Choose Amazon One Medical if…
You want the most authoritative brand-name GLP-1 channel, with same-day delivery and a starting price around $149/mo.
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MadeMed
Compounded GLP-1 in both injection and oral forms
From $219/mo
Get started →Found
Mainstream telehealth GLP-1 access
From $99/mo
Get started →Oak
Compounded semaglutide and tirzepatide at a flat monthly price
From $133/mo
Get started →KairoRx vs Amazon One Medical: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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Or see the full category ranking.
Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.