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Joi + Blokes vs Amazon One Medical

An in-depth comparison of two leading GLP-1 Providers

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By Eli Marsden · Founding Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed
Joi + Blokes logo

Joi + Blokes

7.7
★★★3.9/5

Best for: GLP-1 alongside men's and women's hormone-health programs

Visit Joi + Blokes
VS
Amazon One Medical logo

Amazon One Medical

8.5
★★★★4.3/5

Best for: the most authoritative branded GLP-1 channel with same-day delivery and integrated manufacturer savings

Visit Amazon One Medical

Joi + Blokes and Amazon One Medical are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, Joi + Blokes starts lower at $99/mo versus $149/mo, and Amazon One Medical edges ahead overall (8.5 vs 7.7 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.

Pricing

Joi + Blokes

Compounded semaglutide (first month)Compounded
$99/mo
semaglutide
Compounded semaglutide (months 2+, billed quarterly)Compounded
$199/mo
semaglutide
Compounded tirzepatide (first month)Compounded
$149/mo
tirzepatide
Compounded tirzepatide (months 2+, billed quarterly)Compounded
$299/mo
tirzepatide

Amazon One Medical

Foundayo (with insurance + Lilly Savings Card)Brand-name
$25/mo
orforglipron
Foundayo (cash pay)Brand-name
$149/mo
orforglipron

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What’s included

Joi + Blokes

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Not disclosed

Lab work

Billed separately

Coaching

Included

Amazon One Medical

What the monthly price covers

Medication

Billed separately

Provider visits

Included

Shipping

Included

Lab work

Billed separately

Coaching

Not disclosed

Score breakdown

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

Joi + Blokes

7.7/10

Overall

Amazon One Medical

8.5/10

Value25%

7.0A
vs
B
8.5

Effectiveness25%

8.5A
vs
B
8.5

User Experience15%

8.0A
vs
B
8.0

Trust & Safety15%

7.3A
vs
B
8.8

Accessibility10%

6.5A
vs
B
9.5

Support10%

8.4A
vs
B
8.0

Features & Coverage

FeatureJoi + BlokesAmazon One Medical
Starting Price$99/mo$149/mo
Features7 features6 features
States AvailableNot disclosed50
Compounded✓ Yes
Brand Name✓ Yes
FSA/HSA Accepted
FDA WarningsNoneNone

About Joi + Blokes

Joi + Blokes is a hormone-first telehealth platform with parallel programs for women (Joi) and men (Blokes), now expanded to compounded GLP-1s for weight loss. The integrated hormone-plus-GLP-1 stack is its differentiator versus pure weight-loss telehealth — useful for patients already on testosterone or perimenopausal hormone protocols. Compounded semaglutide runs $99 the first month then $199/mo, and tirzepatide $149 then $299/mo, both billed quarterly.

Read our full Joi + Blokes review →

About Amazon One Medical

Amazon One Medical is the unified Amazon GLP-1 channel — One Medical clinicians prescribe FDA-approved Wegovy, Zepbound, and Foundayo (no compounded products), and Amazon Pharmacy fulfills with same-day delivery across roughly 3,000 US cities plus pickup kiosks at select One Medical locations. No prior membership required; insurance and cash pay both accepted. Foundayo launched at $25/month with insurance and the Lilly Savings Card, or $149/month cash pay.

Read our full Amazon One Medical review →

Pros & Cons

Joi + Blokes

What we like

  • Separate programs for women (Joi) and men (Blokes) — most GLP-1 telehealth is gender-agnostic
  • Trustpilot 4.6/5 from 1,254+ reviews — among the strongest review signals in the category
  • Monthly price includes medication, dosing support, clinician consults, and health coaching
  • Integrated hormone + GLP-1 programs help patients on testosterone or perimenopausal protocols
  • First-month discount ($99 sema / $149 tirz) lowers the barrier to trying GLP-1s

Watch-outs

  • Billed quarterly — a 3-month commitment up front, not month-to-month
  • Different pricing in NY and NJ — verify your state's cost before committing
  • Per-state availability isn't listed; it's zip-code gated behind signup
  • Months 2+ cost more ($199 sema / $299 tirz) than the headline intro price
  • No FDA-approved Wegovy — compounded only on the GLP-1 side; Zepbound carries a separate visit fee
  • No LegitScript or PCAB accreditation badge visible

Amazon One Medical

What we like

  • As low as $1/day ($25/month) for brand-name Foundayo with insurance and the auto-applied Lilly coupon
  • Same-day delivery in nearly 3,000 US cities at launch, expanding to 4,500 by end of 2026
  • In-office pharmacist kiosks at select One Medical clinics let you walk out with Foundayo in hand
  • Cash-pay $5/day ($149/month) is competitive for the same FDA-approved brand-name product
  • Real-time availability, transparent pricing, and automatic manufacturer coupon at checkout
  • Delivering GLP-1 medications since 2021 — track record on cold-chain logistics

Watch-outs

  • Headline $25/month needs both insurance and the Lilly Savings Card — uninsured pay $149/month
  • Same-day delivery is geographically gated; outside major cities it drops to next-day or slower
  • Pricing is set by manufacturer savings programs and can change at any time
  • No compounded options — brand-name only (Foundayo, Wegovy, Zepbound)
  • Wegovy/Zepbound pricing isn't shown upfront — depends on insurance at the prescribing visit
  • Copays and deductibles still apply to the clinical visit

Our Verdict

Winner: Amazon One Medical

Amazon One Medical edges out Joi + Blokes with a higher overall score of 8.5/10 and is particularly strong for the most authoritative branded GLP-1 channel with same-day delivery and integrated manufacturer savings. Joi + Blokes remains a solid alternative, especially if you're looking for GLP-1 alongside men's and women's hormone-health programs.

Choose Joi + Blokes if…

You want GLP-1 alongside men's and women's hormone-health programs and a starting price around $99/mo.

Choose Amazon One Medical if…

You want the most authoritative branded GLP-1 channel with same-day delivery and integrated manufacturer savings and a starting price around $149/mo.

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7.8

Care Bare Rx

LGBTQ+-inclusive compounded GLP-1 telehealth

8.2

Enhance MD

Lab-monitored compounded GLP-1 with mandatory video visit

7.1

MEDVi

Patients who want the option to switch between compounded and brand-name GLP-1 through one provider

Joi + Blokes vs Amazon One Medical: FAQ

Key terms, explained

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Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.