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Joi + Blokes vs Vytora Health

An in-depth comparison of two leading GLP-1 Providers

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By Eli Marsden · Founding Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed
Joi + Blokes logo

Joi + Blokes

7.7
★★★3.9/5

Best for: GLP-1 alongside men's and women's hormone-health programs

Visit Joi + Blokes
VS
Vytora Health logo

Vytora Health

8.4
★★★★4.2/5

Best for: compounded or brand-name GLP-1 with named pharmacy partners, 50 states

Visit Vytora Health

Joi + Blokes and Vytora Health are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, Joi + Blokes starts lower at $99/mo versus $150/mo, and Vytora Health edges ahead overall (8.4 vs 7.7 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.

Pricing

Joi + Blokes

Compounded semaglutide (first month)Compounded
$99/mo
semaglutide
Compounded semaglutide (months 2+, billed quarterly)Compounded
$199/mo
semaglutide
Compounded tirzepatide (first month)Compounded
$149/mo
tirzepatide
Compounded tirzepatide (months 2+, billed quarterly)Compounded
$299/mo
tirzepatide

Vytora Health

All dosesCompounded
$180/mo
semaglutide
3-mo bundle ($450 billed)Compounded
$150/mo
semaglutide
All dosesCompounded
$249/mo
tirzepatide
3-mo bundle ($599 billed)Compounded
$200/mo
tirzepatide
Brand 5/7.5/10/12.5/15 mgBrand-name
$1399/mo
mounjaro
Brand 2.5/5/7.5/10/12.5/15 mgBrand-name
$1399/mo
zepbound

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What’s included

Joi + Blokes

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Not disclosed

Lab work

Billed separately

Coaching

Included

Vytora Health

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

Score breakdown

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

Joi + Blokes

7.7/10

Overall

Vytora Health

8.4/10

Value25%

7.0A
vs
B
8.0

Effectiveness25%

8.5A
vs
B
8.5

User Experience15%

8.0A
vs
B
8.0

Trust & Safety15%

7.3A
vs
B
9.3

Accessibility10%

6.5A
vs
B
8.5

Support10%

8.4A
vs
B
8.4

Features & Coverage

FeatureJoi + BlokesVytora Health
Starting Price$99/mo$150/mo
Features7 features8 features
States AvailableNot disclosed51
Compounded✓ Yes✓ Yes
Brand Name✓ Yes
FSA/HSA Accepted
FDA WarningsNoneNone

About Joi + Blokes

Joi + Blokes is a hormone-first telehealth platform with parallel programs for women (Joi) and men (Blokes), now expanded to compounded GLP-1s for weight loss. The integrated hormone-plus-GLP-1 stack is its differentiator versus pure weight-loss telehealth — useful for patients already on testosterone or perimenopausal hormone protocols. Compounded semaglutide runs $99 the first month then $199/mo, and tirzepatide $149 then $299/mo, both billed quarterly.

Read our full Joi + Blokes review →

About Vytora Health

Vytora Health is a 50-state-plus-DC telehealth platform offering compounded semaglutide and tirzepatide alongside brand-name Mounjaro and Zepbound, plus NAD+ and sermorelin peptides. It names its pharmacy partners publicly — Vials Pharmacy and Greenwich Biosciences — and discloses its operating physician group, uncommon transparency for the category. Compounded semaglutide runs $180/mo ($150 on a 3-month bundle) and tirzepatide $249/mo ($200 bundled).

Read our full Vytora Health review →

Pros & Cons

Joi + Blokes

What we like

  • Separate programs for women (Joi) and men (Blokes) — most GLP-1 telehealth is gender-agnostic
  • Trustpilot 4.6/5 from 1,254+ reviews — among the strongest review signals in the category
  • Monthly price includes medication, dosing support, clinician consults, and health coaching
  • Integrated hormone + GLP-1 programs help patients on testosterone or perimenopausal protocols
  • First-month discount ($99 sema / $149 tirz) lowers the barrier to trying GLP-1s

Watch-outs

  • Billed quarterly — a 3-month commitment up front, not month-to-month
  • Different pricing in NY and NJ — verify your state's cost before committing
  • Per-state availability isn't listed; it's zip-code gated behind signup
  • Months 2+ cost more ($199 sema / $299 tirz) than the headline intro price
  • No FDA-approved Wegovy — compounded only on the GLP-1 side; Zepbound carries a separate visit fee
  • No LegitScript or PCAB accreditation badge visible

Vytora Health

What we like

  • All 50 states plus DC, with per-state video-vs-audio compliance disclosed
  • Both compounded and brand-name options on one platform — uncommon
  • LegitScript Approved and HIPAA compliant
  • Pharmacy partners named publicly: Vials Pharmacy (TX) and Greenwich Biosciences
  • Operating entity disclosed: Wasef Health, PC (Pinellas Park, FL)
  • Competitive monthly pricing ($180 sema / $249 tirz) plus a 3-month bundle saving 17%
  • Brand-name Mounjaro and Zepbound available at $1,399/mo for FDA-approved options

Watch-outs

  • Brand-name Mounjaro/Zepbound at $1,399/mo is near retail — insured patients may do better via LillyDirect Self Pay ($449-$699/mo)
  • Compounded tirzepatide at $249/mo is mid-market, above the $149-199 floor
  • Dose tiers aren't broken out — 'all doses included' means low-dose patients pay the same as high-dose
  • Initial consultation cost not shown on the public pricing page
  • Limited per-prescriber state licensure detail

Our Verdict

Winner: Vytora Health

Vytora Health edges out Joi + Blokes with a higher overall score of 8.4/10 and is particularly strong for compounded or brand-name GLP-1 with named pharmacy partners, 50 states. Joi + Blokes remains a solid alternative, especially if you're looking for GLP-1 alongside men's and women's hormone-health programs.

Choose Joi + Blokes if…

You want GLP-1 alongside men's and women's hormone-health programs and a starting price around $99/mo.

Choose Vytora Health if…

You want compounded or brand-name GLP-1 with named pharmacy partners, 50 states and a starting price around $150/mo.

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Joi + Blokes vs Vytora Health: FAQ

Key terms, explained

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Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.