HumeCare+ vs TMates
In our scoring, HumeCare+ edges ahead overall (7.2 vs 6.9 out of 10), and HumeCare+ costs less for compounded semaglutide (about $600 a year less).
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Key differences
- Price
- HumeCare+ $199/mo vs TMates $249/mo for compounded semaglutide (standing prices, no prepay or separate membership listed · about $600 a year less with HumeCare+)
- Coverage
- HumeCare+ 46 states + DC; TMates 50 states (only HumeCare+: District of Columbia · only TMates: Alabama, Arkansas, Louisiana and 1 more)
- Included
- HumeCare+: medication, clinician visits; TMates: medication, clinician visits, shipping, coaching
HumeCare+
Affiliate partnerBest for GLP-1 weight loss with real-time body-composition tracking to protect muscle
semaglutide
$199
Our score 7.2/10
TMates
Affiliate partnerBest for nationwide compounded GLP-1 availability including Puerto Rico
semaglutide
$249
Our score 6.9/10
We may earn a commission if you sign up through these links. Partner status can affect which provider we feature; it never changes a score or a price.
Costs & coverage
Published prices with their terms attached. Yearly figures are modeled from the standing price and billing cadence. A check mark marks the better side, on like-for-like rows only.
HumeCare+
TMates
Price
Semaglutide / month
Better on this row: $199/mo
$249/mo
Semaglutide / year (modeled)
Better on this row: $2,388
$2,988
Tirzepatide / month
$299/mo
Better on this row: $297/mo
Tirzepatide / year (modeled)
$3,588
Better on this row: $3,564
Oral semaglutide / month
$199/mo
Not listed
Coverage
State availability
46 states + DC
50 states
Oral option listed
Yes
Not listed
Included in the price
Medication, clinician visits
Medication, clinician visits, shipping, coaching
Terms & safety
Price shown
Plan quoted after intake; a price is published
Before intake
Cancel anytime
Yes
Yes
Minimum commitment
None
None
Refunds
Terms: if the physician finds you ineligible the plan is refunded automatically and the Hume Pod must be returned. Otherwise there are no pro-rated refunds, and cancellation must be at least 48 hours before the renewal date. A clinical consultation fee assessed at enrollment and at each refill is carved out as non-refundable; its amount is not published.
Not disclosed
Early-cancellation fee
None
Not disclosed
FDA warning letters
None on record
None on record
Provider facts checked
August 2026
August 2026
Show where they differ by stateHide state lists
Only HumeCare+ (DC)
- District of Columbia
Only TMates (4 states)
- Alabama
- Arkansas
- Louisiana
- Mississippi
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Which fits your priorities?
Only the points where these two differ, from the table above and each provider’s record.
Choose HumeCare+ if…
- About $600 a year less than TMates for compounded semaglutide at standing prices
- Lists oral compounded semaglutide, which TMates doesn't price
- Serves District of Columbia, where TMates doesn't
What to weigh up
- Not available in 4 states that TMates serves
- No price appears on the marketing site; you must finish the intake quiz and give your name before one is quoted
Choose TMates if…
- Serves 4 states that HumeCare+ doesn't
- All-inclusive monthly price covers medication, consults, nutrition coaching, and 24/7 support — no separate membership fee
- Fast stated turnaround — 2–3 days from intake to delivery
What to weigh up
- About $600 a year more than HumeCare+ for compounded semaglutide
- Not available in District of Columbia
Explore the scoring factors
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
HumeCare+
7.2/10
TMates
6.9/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
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Found
Compounded GLP-1 with medication included from $169/mo cash, plus insurance help for brand GLP-1s
Read full review →From $169/mo
Get started →GobyMeds
No-membership, no-auto-renew compounded GLP-1 orders, from about $99/mo on a 3-month bundle
Read full review →From $169/mo
Get started →Ivim Health
Compounded GLP-1 with weekly provider check-ins and health coaches, under a required monthly membership
Read full review →From $65/mo + membership
Get started →HumeCare+ vs TMates: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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Or see the full category ranking.
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