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Fresh Day Meds vs NewSelf

An in-depth comparison of two leading GLP-1 Providers

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By Eli Marsden · Founding Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed
Fresh Day Meds logo

Fresh Day Meds

7.8
★★★3.9/5

Best for: lowest-cost compounded GLP-1 from a LegitScript-certified Texas platform

Visit Fresh Day Meds
VS
NewSelf logo

NewSelf

8.3
★★★★4.2/5

Best for: lowest-cost compounded GLP-1 with pharmacy quality transparency

Visit NewSelf

Fresh Day Meds and NewSelf are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, NewSelf starts lower at $100/mo versus $133/mo, and NewSelf edges ahead overall (8.3 vs 7.8 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.

Pricing

Fresh Day Meds

All doses (3-mo bundle, $399 billed)Compounded
$133/mo
semaglutide
All doses (1-mo)Compounded
$160/mo
semaglutide
All doses (3-mo bundle, $499 billed)Compounded
$166/mo
tirzepatide
All doses (1-mo)Compounded
$199/mo
tirzepatide

NewSelf

Semaglutide+ (best price)Compounded
$100/mo
semaglutide

All dosages same price

Semaglutide+ (regular)Compounded
$135/mo
semaglutide
Tirzepatide+ (best price)Compounded
$144/mo
tirzepatide

All dosages same price

Tirzepatide+ (regular)Compounded
$225/mo
tirzepatide

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What’s included

Fresh Day Meds

What the monthly price covers

Medication

Included

Provider visits

Not disclosed

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

NewSelf

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

Score breakdown

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

Fresh Day Meds

7.8/10

Overall

NewSelf

8.3/10

Value25%

8.0A
vs
B
9.0

Effectiveness25%

8.0A
vs
B
8.0

User Experience15%

8.0A
vs
B
8.0

Trust & Safety15%

7.8A
vs
B
8.3

Accessibility10%

8.0A
vs
B
8.5

Support10%

6.5A
vs
B
7.9

Features & Coverage

FeatureFresh Day MedsNewSelf
Starting Price$133/mo$100/mo
Features8 features6 features
States Available5049
Compounded✓ Yes✓ Yes
Brand Name
FSA/HSA Accepted
FDA WarningsNoneNone

About Fresh Day Meds

Fresh Day Meds is a Houston-based, LegitScript-certified telehealth platform offering compounded semaglutide and tirzepatide alongside hair, sexual-wellness, testosterone, and daily-wellness products on one account. It bundles the consultation fee into the medication price and ships free with prescription review in under four hours. Among the lowest in the segment — semaglutide from $133/mo and tirzepatide from $166/mo on the 3-month plan.

Read our full Fresh Day Meds review →

About NewSelf

NewSelf offers compounded semaglutide+ (with B12/Glycine, from $99.97/mo) and compounded tirzepatide+ (with B6/Glycine, from $144.49/mo). LegitScript certified. Available in 48 states + Puerto Rico. Uses 503A licensed pharmacies with third-party testing.

Read our full NewSelf review →

Pros & Cons

Fresh Day Meds

What we like

  • Among the lowest compounded GLP-1 pricing in the market ($133/mo sema, $166/mo tirz on 3-month bundle)
  • LegitScript certified and HIPAA compliant
  • Coverage across 49 states plus DC
  • Free expedited shipping with prescription review in under 4 hours
  • No membership or consultation fees on top of medication price
  • Single account covers GLP-1, hair, sexual wellness, TRT, and NAD+/B12
  • Houston, TX headquarters publicly disclosed

Watch-outs

  • Compounding pharmacy partner not named — only 503A/503B facilities referenced
  • Medical director and founder names not disclosed
  • Compounded-only — no brand-name fallback if the FDA shortage pathway ends
  • State count is inconsistent: ToS lists 49 states + DC (no Arkansas) while About page claims all 50 + DC
  • Dose-specific pricing not shown — only flat 'as low as' pricing before checkout
  • Medical group operates as Telegra MD LLC (Spokane, WA) — a typical white-label arrangement

NewSelf

What we like

  • Semaglutide+ from $99.97/mo — among the lowest prices in the dataset
  • All dosages at the same price — no price escalation as dose increases
  • LegitScript certified with 503A licensed pharmacies
  • Third-party potency, sterility, and endotoxicity testing
  • 48 states + Puerto Rico coverage
  • B12/B6 + Glycine enhanced formulations
  • No membership fees

Watch-outs

  • Not available in Mississippi and Louisiana
  • Compounded only — no brand-name options
  • Site also promotes AI health optimization and longevity (broader platform)

Our Verdict

Winner: NewSelf

NewSelf edges out Fresh Day Meds with a higher overall score of 8.3/10 and is particularly strong for lowest-cost compounded GLP-1 with pharmacy quality transparency. Fresh Day Meds remains a solid alternative, especially if you're looking for lowest-cost compounded GLP-1 from a LegitScript-certified Texas platform.

Choose Fresh Day Meds if…

You want lowest-cost compounded GLP-1 from a LegitScript-certified Texas platform and a starting price around $133/mo.

Choose NewSelf if…

You want lowest-cost compounded GLP-1 with pharmacy quality transparency and a starting price around $100/mo.

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Fresh Day Meds vs NewSelf: FAQ

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