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Fresh Day Meds vs Amazon One Medical

An in-depth comparison of two leading GLP-1 Providers

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By Eli Marsden · Founding Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed
Fresh Day Meds logo

Fresh Day Meds

7.8
★★★3.9/5

Best for: lowest-cost compounded GLP-1 from a LegitScript-certified Texas platform

Visit Fresh Day Meds
VS
Amazon One Medical logo

Amazon One Medical

8.5
★★★★4.3/5

Best for: the most authoritative branded GLP-1 channel with same-day delivery and integrated manufacturer savings

Visit Amazon One Medical

Fresh Day Meds and Amazon One Medical are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, Fresh Day Meds starts lower at $133/mo versus $149/mo, and Amazon One Medical edges ahead overall (8.5 vs 7.8 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.

Pricing

Fresh Day Meds

All doses (3-mo bundle, $399 billed)Compounded
$133/mo
semaglutide
All doses (1-mo)Compounded
$160/mo
semaglutide
All doses (3-mo bundle, $499 billed)Compounded
$166/mo
tirzepatide
All doses (1-mo)Compounded
$199/mo
tirzepatide

Amazon One Medical

Foundayo (with insurance + Lilly Savings Card)Brand-name
$25/mo
orforglipron
Foundayo (cash pay)Brand-name
$149/mo
orforglipron

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What’s included

Fresh Day Meds

What the monthly price covers

Medication

Included

Provider visits

Not disclosed

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

Amazon One Medical

What the monthly price covers

Medication

Billed separately

Provider visits

Included

Shipping

Included

Lab work

Billed separately

Coaching

Not disclosed

Score breakdown

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

Fresh Day Meds

7.8/10

Overall

Amazon One Medical

8.5/10

Value25%

8.0A
vs
B
8.5

Effectiveness25%

8.0A
vs
B
8.5

User Experience15%

8.0A
vs
B
8.0

Trust & Safety15%

7.8A
vs
B
8.8

Accessibility10%

8.0A
vs
B
9.5

Support10%

6.5A
vs
B
8.0

Features & Coverage

FeatureFresh Day MedsAmazon One Medical
Starting Price$133/mo$149/mo
Features8 features6 features
States Available5050
Compounded✓ Yes
Brand Name✓ Yes
FSA/HSA Accepted
FDA WarningsNoneNone

About Fresh Day Meds

Fresh Day Meds is a Houston-based, LegitScript-certified telehealth platform offering compounded semaglutide and tirzepatide alongside hair, sexual-wellness, testosterone, and daily-wellness products on one account. It bundles the consultation fee into the medication price and ships free with prescription review in under four hours. Among the lowest in the segment — semaglutide from $133/mo and tirzepatide from $166/mo on the 3-month plan.

Read our full Fresh Day Meds review →

About Amazon One Medical

Amazon One Medical is the unified Amazon GLP-1 channel — One Medical clinicians prescribe FDA-approved Wegovy, Zepbound, and Foundayo (no compounded products), and Amazon Pharmacy fulfills with same-day delivery across roughly 3,000 US cities plus pickup kiosks at select One Medical locations. No prior membership required; insurance and cash pay both accepted. Foundayo launched at $25/month with insurance and the Lilly Savings Card, or $149/month cash pay.

Read our full Amazon One Medical review →

Pros & Cons

Fresh Day Meds

What we like

  • Among the lowest compounded GLP-1 pricing in the market ($133/mo sema, $166/mo tirz on 3-month bundle)
  • LegitScript certified and HIPAA compliant
  • Coverage across 49 states plus DC
  • Free expedited shipping with prescription review in under 4 hours
  • No membership or consultation fees on top of medication price
  • Single account covers GLP-1, hair, sexual wellness, TRT, and NAD+/B12
  • Houston, TX headquarters publicly disclosed

Watch-outs

  • Compounding pharmacy partner not named — only 503A/503B facilities referenced
  • Medical director and founder names not disclosed
  • Compounded-only — no brand-name fallback if the FDA shortage pathway ends
  • State count is inconsistent: ToS lists 49 states + DC (no Arkansas) while About page claims all 50 + DC
  • Dose-specific pricing not shown — only flat 'as low as' pricing before checkout
  • Medical group operates as Telegra MD LLC (Spokane, WA) — a typical white-label arrangement

Amazon One Medical

What we like

  • As low as $1/day ($25/month) for brand-name Foundayo with insurance and the auto-applied Lilly coupon
  • Same-day delivery in nearly 3,000 US cities at launch, expanding to 4,500 by end of 2026
  • In-office pharmacist kiosks at select One Medical clinics let you walk out with Foundayo in hand
  • Cash-pay $5/day ($149/month) is competitive for the same FDA-approved brand-name product
  • Real-time availability, transparent pricing, and automatic manufacturer coupon at checkout
  • Delivering GLP-1 medications since 2021 — track record on cold-chain logistics

Watch-outs

  • Headline $25/month needs both insurance and the Lilly Savings Card — uninsured pay $149/month
  • Same-day delivery is geographically gated; outside major cities it drops to next-day or slower
  • Pricing is set by manufacturer savings programs and can change at any time
  • No compounded options — brand-name only (Foundayo, Wegovy, Zepbound)
  • Wegovy/Zepbound pricing isn't shown upfront — depends on insurance at the prescribing visit
  • Copays and deductibles still apply to the clinical visit

Our Verdict

Winner: Amazon One Medical

Amazon One Medical edges out Fresh Day Meds with a higher overall score of 8.5/10 and is particularly strong for the most authoritative branded GLP-1 channel with same-day delivery and integrated manufacturer savings. Fresh Day Meds remains a solid alternative, especially if you're looking for lowest-cost compounded GLP-1 from a LegitScript-certified Texas platform.

Choose Fresh Day Meds if…

You want lowest-cost compounded GLP-1 from a LegitScript-certified Texas platform and a starting price around $133/mo.

Choose Amazon One Medical if…

You want the most authoritative branded GLP-1 channel with same-day delivery and integrated manufacturer savings and a starting price around $149/mo.

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Fresh Day Meds vs Amazon One Medical: FAQ

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Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.