Enhance MD vs TrimRx
In our scoring, Enhance MD edges ahead overall (8.2 vs 7.7 out of 10), and TrimRx costs less for compounded semaglutide (about $396 a year less).
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Key differences
- Price
- TrimRx $179/mo vs Enhance MD $212/mo for compounded semaglutide (standing prices, no prepay or separate membership listed · about $396 a year less with TrimRx)
- Coverage
- Enhance MD 39 states (TrimRx doesn't publish a state list)
- Included
- Enhance MD: medication, clinician visits, labs; TrimRx: medication, clinician visits, shipping
Enhance MD
Affiliate partnerBest for lab-monitored compounded GLP-1 with mandatory video visit
semaglutide
$212
$112 first month
Our score 8.2/10
TrimRx
Affiliate partnerBest for best overall value
semaglutide
$179
$149 first month
Our score 7.7/10
We may earn a commission if you sign up through these links. Partner status can affect which provider we feature; it never changes a score or a price.
Costs & coverage
Published prices with their terms attached. Yearly figures are modeled from the standing price and billing cadence. A check mark marks the better side, on like-for-like rows only.
Enhance MD
TrimRx
Price
Semaglutide / month
$212/mo
$112 first month
Better on this row: $179/mo
$149 first month
Semaglutide / year (modeled)
$2,544
Better on this row: $2,148
Tirzepatide / month
Better on this row: $169/mo
$259/mo
Tirzepatide / year (modeled)
Better on this row: $2,028
$3,108
Brand Wegovy / Ozempic / month
Not listed
$1,579/mo
Brand Zepbound / Mounjaro / month
Not listed
$1,249/mo
Coverage
State availability
39 states
List not published
Brand-name access listed
Not listed
Wegovy / Ozempic, Zepbound / Mounjaro
Included in the price
Medication, clinician visits, labs
Medication, clinician visits, shipping
Terms & safety
Price shown
Before intake
Before intake
Lab work
Required
Not disclosed
Video visit
Required
Not disclosed
Cancel anytime
Yes
Not disclosed
Minimum commitment
None
Not disclosed
FDA warning letters
None on record
None on record
Provider facts checked
August 2026
August 2026
Every dose and plan: Enhance MD · TrimRx
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Which fits your priorities?
Only the points where these two differ, from the table above and each provider’s record.
Choose Enhance MD if…
- Publishes its full state list (39 states)
- Baseline and ongoing metabolic labs (CMP, lipids, TSH, HbA1c) at Quest every 6 months — rare for compounded GLP-1
- Mandatory video visit with a US-licensed MD or NP before your first prescription — not a pure questionnaire model
What to weigh up
- About $396 a year more than TrimRx for compounded semaglutide
- Compounded only — no FDA-approved Ozempic, Wegovy, Zepbound, or Mounjaro
Choose TrimRx if…
- About $396 a year less than Enhance MD for compounded semaglutide at standing prices
- Lists brand-name Wegovy / Ozempic and brand-name Zepbound / Mounjaro, which Enhance MD doesn't price
- Free shipping with medication delivered to your door monthly — can start as soon as the next day
What to weigh up
- No published state list; confirm yours at signup
- Async, questionnaire-based intake — no mandatory video visit with a clinician before prescribing
Explore the scoring factors
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
Enhance MD
8.2/10
TrimRx
7.7/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
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Ivim Health
Compounded GLP-1 with weekly provider check-ins and health coaches, under a required monthly membership
Read full review →From $65/mo + membership
Get started →From $247/mo
Get started →From $139/mo
Get started →Enhance MD vs TrimRx: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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Or see the full category ranking.
Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.