Enhance MD vs Lttl
In our scoring, Enhance MD edges ahead overall (8.2 vs 7.2 out of 10), and Lttl costs less for compounded semaglutide (about $1,257 a year less; one bills every 4 weeks (13 charges a year), so this compares modeled yearly cost).
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Key differences
- Price
- Lttl $99/mo vs Enhance MD $212/mo for compounded semaglutide (standing prices, no prepay or separate membership listed · about $1,257 a year less with Lttl · one bills every 4 weeks (13 charges a year), so this compares modeled yearly cost)
- Coverage
- Enhance MD 39 states (Lttl doesn't publish a state list)
- Included
- Enhance MD: medication, clinician visits, labs; Lttl: medication, clinician visits, shipping
Enhance MD
Affiliate partnerBest for lab-monitored compounded GLP-1 with mandatory video visit
semaglutide
$212
$112 first month
Our score 8.2/10

Lttl
Affiliate partnerBest for every commitment tier priced openly, plus a low-dose microdose option
semaglutide
$99
billed every 4 weeks
Our score 7.2/10
We may earn a commission if you sign up through these links. Partner status can affect which provider we feature; it never changes a score or a price.
Costs & coverage
Published prices with their terms attached. Yearly figures are modeled from the standing price and billing cadence. A check mark marks the better side, on like-for-like rows only.
Enhance MD
Lttl
Price
Semaglutide / month
$212/mo
$112 first month
Better on this row: $99/mo
billed every 4 weeks
Semaglutide / year (modeled)
$2,544
Better on this row: $1,287
13 charges
Tirzepatide / month
$169/mo
Better on this row: $149/mo
billed every 4 weeks
Tirzepatide / year (modeled)
$2,028
Better on this row: $1,937
13 charges
Oral semaglutide / month
Not listed
$179/mo
$149 first month
Coverage
State availability
39 states
List not published
Oral option listed
Not listed
Yes
Included in the price
Medication, clinician visits, labs
Medication, clinician visits, shipping
FSA/HSA accepted
Not listed
Yes
Terms & safety
Price shown
Before intake
Before intake
Lab work
Required
Not disclosed
Video visit
Required
Not disclosed
Cancel anytime
Yes
Yes
Minimum commitment
None
None on the monthly plan; 3-, 6- and 12-month prepay tiers offered at lower per-month rates
FDA warning letters
None on record
None on record
Provider facts checked
August 2026
October 2026
Every dose and plan: Enhance MD · Lttl
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Which fits your priorities?
Only the points where these two differ, from the table above and each provider’s record.
Choose Enhance MD if…
- Publishes its full state list (39 states)
- Baseline and ongoing metabolic labs (CMP, lipids, TSH, HbA1c) at Quest every 6 months — rare for compounded GLP-1
- Mandatory video visit with a US-licensed MD or NP before your first prescription — not a pure questionnaire model
What to weigh up
- About $1,257 a year more than Lttl for compounded semaglutide (one bills every 4 weeks (13 charges a year), so this compares modeled yearly cost)
- Compounded only — no FDA-approved Ozempic, Wegovy, Zepbound, or Mounjaro

Choose Lttl if…
- About $1,257 a year less than Enhance MD for compounded semaglutide at standing prices (one bills every 4 weeks (13 charges a year), so this compares modeled yearly cost)
- Lists oral compounded semaglutide, which Enhance MD doesn't price
- Accepts FSA/HSA cards
What to weigh up
- No published state list; confirm yours at signup
- Partner pharmacies are never named — the site refers only to 'a partner U.S. pharmacy' (a material disclosure gap for a YMYL purchase)
Explore the scoring factors
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
Enhance MD
8.2/10
Lttl
7.2/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
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GobyMeds
No-membership, no-auto-renew compounded GLP-1 orders, from about $99/mo on a 3-month bundle
Read full review →From $169/mo
Get started →Ivim Health
Compounded GLP-1 with weekly provider check-ins and health coaches, under a required monthly membership
Read full review →From $65/mo + membership
Get started →From $247/mo
Get started →Enhance MD vs Lttl: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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Or see the full category ranking.
Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.